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117 Possible Causes for Clubbing of Nails, Splenomegaly

  • Liver Cirrhosis

    We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] (only in biliary cirrhosis) Terry’s “half & half” nails Duputryen's contracture ( Credit ) Petechiae and echymosis Scratch marks Edema Testicular atrophy (and how do you[stanfordmedicine25.stanford.edu] Terry's nails – proximal two-thirds of the nail plate appears white with distal one-third red, also due to hypoalbuminemia Clubbing – angle between the nail plate and proximal[en.wikipedia.org]

  • Portal Cirrhosis

    Liver cirrhosis: Liver cirrhosis with an inhomogeneous liver with irregular contour and ascites and splenomegaly Liver cirrhosis: Liver cirrhosis with an irregular liver contour[ultrasoundcases.info] Clubbing of the nails Palmar erythema – redness on the thenar and hypothenar eminences Spider naevi – swollen blood vessels under the skin radiating like a spiders web Telangiectasia[kenhub.com] […] with ground glass opacity Clubbed nails Hormone disorders Hyperestrogenism Changes in the hepatic metabolization of sex hormones causes an imbalance in the estrogen‑androgen[amboss.com]

  • Subacute Bacterial Endocarditis

    Fever, anaemia, splenomegaly and positive blood cultures for Gram-negative bacteria were found on admission.[ncbi.nlm.nih.gov] The nail moves more freely in patients with clubbing; therefore, the examiner may note a spongy sensation as the nail is pressed toward the nail plate.[emedicine.medscape.com] Findings compatible with both SBE and marantic endocarditis due to a B-cell lymphoproliferative disorder included an elevated ESR, and splenomegaly.[ncbi.nlm.nih.gov]

  • Hepatitis

    Dehydration with drying of mucous membranes Telangiectasis (spider angiomata) and esophageal varices Jaundice Ascites Utricarial rashes Portal Hypertension Hepatomegaly and Splenomegaly[symptoma.com] ; thickening and widening of the fingers and nails (clubbing); liver enlargement or inflammation; and abnormal accumulation of fat in normal liver cells (fatty infiltration[web.archive.org] Physical examination may be without pathological findings, but may also reveal hepatomegaly, splenomegaly, jaundice, and signs and symptoms of chronic liver disease[ 1 9 ][doi.org]

  • Alcoholic Liver Disease

    Splenomegaly : Portal hypertension causes the spleen to enlarge (a condition called splenomegaly).[msdmanuals.com] […] in your abdomen caused by a build-up of fluid known as ascites a high temperature (fever) and shivering attacks very itchy skin hair loss unusually curved fingertips and nails[nhs.uk] […] steatosis (fatty liver) From the collection of Dr McClain; used with permission History & Exam Key Factors abdominal pain hepatomegaly hematemesis and melena venous collaterals splenomegaly[online.epocrates.com]

  • Infective Endocarditis

    This score includes clinical, epidemiological (male, fever, splenomegaly, clubbing, vascular disease and stroke) and biological criteria (Leucocytes 10,000/mm3, sedimentation[ncbi.nlm.nih.gov] With prolonged infection, clubbing of the fingers may also occur.[rarediseases.org] Additional findings may include splenomegaly, gallop or arrhythmia, pericardial or pleural rubs, rales, pallor, acute septic monoarticular arthritis or delirium.[symptoma.com]

  • Bacterial Endocarditis

    The condition is characterized by heart murmur, prolonged fever, bacteremia, splenomegaly, and embolic phenomena.[medical-dictionary.thefreedictionary.com] With prolonged infection, clubbing of the fingers may also occur.[rarediseases.org] There can been present splenomegaly, tachycardia, petechiae on the skin occur in about 10-15% of patients usually appear in groups 2-3 days and fade away and disappear without[remedyland.com]

  • Endocarditis

    PATIENT CONCERNS: A young woman, with a history of aortic stenosis, was admitted to our unit for a month of intermittent fever associated with a new diastolic heart murmur and splenomegaly[ncbi.nlm.nih.gov] With prolonged infection, clubbing of the fingers may also occur.[rarediseases.org] Signs and symptoms include fever, chills, sweating, malaise, weakness, anorexia, weight loss, splenomegaly, flu-like feeling, cardiac murmur, heart failure, petechia (red[en.wikipedia.org]

  • Castleman Disease

    Older age ( 40 years), splenomegaly, and hypoalbuminemia were risk factors for poorer MCD prognosis. 2017 The Authors.[ncbi.nlm.nih.gov] Other skin changes, including whitening of the proximal nails (Terry nails), peripheral edema, hyperhidrosis, clubbing of the fingers, Raynaud's phenomenon, and angiomas can[clinicaladvisor.com] The disease is characterized by fever, weight loss, anemia, polyclonal hyperglobulinemia, splenomegaly, thrombocytosis and peripheral lymphadenopathy.[ncbi.nlm.nih.gov]

  • Viral Hepatitis

    […] changes – clubbing, flat and brittle nails , opaque white nails (Terry nails ), parallel white lines (Muehrcke lines) Loss of armpit and pubic hair – due to hormonal changes[dermnetnz.org] […] changes – clubbing, flat and brittle nails, opaque white nails (Terry nails ), parallel white lines (Muehrcke lines) Loss of armpit and pubic hair – due to hormonal changes[dermnetnz.org] […] thin skin ( atrophy ) Palmar erythema – red palms Caput medusa – distended veins radiating from the umbilicus Scratch marks and nodular prurigo due to severe itch Dry skin Nail[dermnetnz.org]

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