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1,784 Possible Causes for Clumsiness, Muscle Weakness

  • Duchenne Muscular Dystrophy

    Occasionally, however, females who carry a DMD gene mutation may have muscle weakness and cramping.[ghr.nlm.nih.gov] DMD typically appears between the ages of two with weakness in the pelvis and upper limbs, resulting in clumsiness, frequent falling, an unusual gait and general weakness.[medterms.com] Additional early signs and symptoms include: Developmental delay Muscle weakness Clumsiness Waddling gait Difficulty or inability to perform activities such as climbing stairs[pfizer.com]

  • Chronic Inflammatory Demyelinating Polyneuropathy

    […] of the muscle weakness.[ncbi.nlm.nih.gov] Patients with leg weakness show clumsy gait, tripping on uneven ground, and difficulty standing still, in stepping onto a curb, in going up or down stairs or on arising from[providence.net] My gait got clumsy and I was falling frequently. My feet felt like they were on fire, the pain was excruciating. Over time, I lost over 50 pounds.[globalgenes.org]

  • Mucopolysaccharidosis

    Compression of the cervical spinal cord, caused by glycosaminoglycan infiltration of the dura, may lead to spastic paresis if not corrected by neurosurgical intervention.[orpha.net] […] children who have Hunter syndrome but may be underdiagnosed, for patients’ cognitive impairment often prevents them from accurately describing their symptoms. 17,25 Manual clumsiness[touchneurology.com] Nursing Diagnosis - Self care deficit related to inability to carryout ADLS / tremors - Impaired physical mobility related to weakness of bones and muscles - Risk for injury[slideshare.net]

  • Niemann-Pick Disease Type C

    Cataplexy is the sudden muscle weakness brought on by strong emotions, particularly joking, laughter, or anger.[ncbi.nlm.nih.gov] One of the twins presented with a history of obsessive-compulsive disorder and slowly progressive inferior limb clumsiness, dysphagia and dysarthria.[ncbi.nlm.nih.gov] It is characterized clinically by a variety of progressive, disabling neurological symptoms including clumsiness, limb and gait ataxia, dysarthria, dysphagia and cognitive[ncbi.nlm.nih.gov]

  • Alpha-Mannosidosis

    Symptoms of the moderate form of alpha-mannosidosis include: coarse facial features hypotonia skeletal abnormalities mental retardation progressive muscle weakness hearing[egl-eurofins.com] Mental and motor development is delayed, but in this context, the progressive course of AM has to be considered: Affected children often appear clumsy, and milestones in speech[symptoma.com] Associated motor function disturbances The development of motor functions in affected patients is generally slow, and the children appear clumsy.[ojrd.com]

  • Primary Lateral Sclerosis

    Symptoms may include: Muscle weakness and spasms beginning in the legs and progressing to the trunk, arms and eventually the face Difficulty in walking and maintaining balance[symptoma.com] This loss causes movement problems, such as slow movements, balance problems and clumsiness.[mayoclinic.org] Unilateral limb slowness or clumsiness was the initial complaint in four, and bulbar symptoms in one.[ncbi.nlm.nih.gov]

  • Motor Neuron Disease

    Onset was in the second to fourth decade with finger extension weakness, progressing to other distal and sometimes more proximal muscles.[ncbi.nlm.nih.gov] The patient had noted clumsiness and weakness in all extremities 5 years before presentation of abnormal eye movements.[ncbi.nlm.nih.gov] Generally, symptoms consist of stiffness, clumsiness, and awkward movements, usually affecting first the mouth, throat, or both, then spreading to the limbs.[merckmanuals.com]

  • Narcolepsy-Cataplexy Syndrome

    A 20-year-old male presented with a 12-year history of excessive daytime sleepiness and sudden muscle weakness caused by laughter and disturbed nocturnal sleep.[ncbi.nlm.nih.gov] A subjective sense of clumsiness, slurred speech, weakness, and muscle twitches are reported prior to the attack.[symptoma.com] Without much warning, the person loses muscle tone and can have a slack jaw, broken speech, buckled knees or total weakness in their face, arms, legs, and trunk.[sleepfoundation.org]

  • Muscular Dystrophy

    It causes progressive weakness in muscles of the face, arms, legs, and around the shoulders and chest.[ninds.nih.gov] Initial symptoms: Progressive weakening of muscles Enlargement of muscles as they weaken Muscle cramping Clumsiness Frequent falling and difficulty getting up Later symptoms[neurosciences.uvahealth.com] When to see a doctor Seek medical advice if you notice signs of muscle weakness — such as increased clumsiness and falling — in yourself or your child.[mayoclinic.org]

  • Niemann-Pick Disease

    Symptoms include: Severe muscle weakness Poor muscle tone Lack of growth and weight gain in infants An enlarged heart, liver, or tongue Tay-Sachs disease: This is caused by[webmd.com] Niemann-Pick care at Mayo Clinic Symptoms Niemann-Pick signs and symptoms may include: Clumsiness and difficulty walking Excessive muscle contractions (dystonia) or eye movements[mayoclinic.org] […] after) birth An enlarged spleen and/or liver (hepatosplenamegaly) Difficulty with upward and downward eye movements (Vertical Supranuclear Gaze Palsy) Unsteadiness of gait, clumsiness[npuk.org]

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