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37 Possible Causes for Clumsy Gait, Creatine Phosphokinase Increased, Pediatric Disorder

  • Duchenne Muscular Dystrophy

    BACKGROUND AND PURPOSE: Duchenne muscular dystrophy (DMD) is a lethal progressive pediatric muscle disorder and genetically inherited as an X-linked disease that caused by[ncbi.nlm.nih.gov] Additional early signs and symptoms include: Developmental delay Muscle weakness Clumsiness Waddling gait Difficulty or inability to perform activities such as climbing stairs[pfizer.com] Nelson Textbook of Pediatrics. 17th ed. Philadelphia, PA: Elsevier Saunders; 2005:2060-9. Acsadi G. Duchenne Muscular Dystrophy. NORD Guide to Rare Disorders.[rarediseases.org]

  • Becker Muscular Dystrophy

    Little is known about parental motivations and expectations for clinical trials for rare pediatric disorders.[ncbi.nlm.nih.gov] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] Walking on the toes or balls of the feet Clumsiness, falling often Trouble climbing stairs Difficulty rising from a lying or sitting position Larger-than-normal calves that[webmd.com]

  • Glycogen Storage Disease Type 2

    Nomenclature for Conditions based upon “Naming and Counting Disorders (Conditions) Included in Newborn Screening Panels.” Pediatrics. 2006; 117 (5) Suppl: S308-S314.[hrsa.gov] Patients with the latter two types may manifest with primarily neurologic symptoms of clumsiness, gait disturbance, worsening of coordination, and fine motor skills, or with[dx.doi.org] Dowling, Myopathies and Myotonic Disorders, Pediatric Electromyography, 10.1007/978-3-319-61361-1_22, (327-354), (2017). G. Chalès and P.[dx.doi.org]

  • Muscular Dystrophy

    We offer children and families coordinated care for the diagnosis and treatment of muscular dystrophy and other pediatric neuromuscular disorders.[ynhh.org] The diagnosis of muscular dystrophy is based on the results of muscle biopsy, increased creatine phosphokinase (CpK3), electromyography, and genetic testing.[en.wikipedia.org] Other symptoms include loss of some reflexes, a waddling gait, frequent falls and clumsiness (especially when running), difficulty when rising from a sitting or lying position[web.archive.org]

  • Brain Abscess

    L. ( 1981 ) Sinusitis and its Complications in a Pediatric Patient. Pediatric Clinics of North America, 28 ( 4 ): 777 – 796. Weisberg, L.[journals.cambridge.org] My GP sees immediately that my gait is clumsy, my focus wild, my speech slurring.[theguardian.com] A. ( 1980 ) Cerebral Computerized Tomography in Intracranial Inflammatory Disorders. Archives of Neurosurgery, 37 : 137 – 142. Williams, B. ( 1982 ). Subdural Empyema.[journals.cambridge.org]

  • Central Nervous System Disorder

    […] neuro-immunology and pediatric multiple sclerosis and related disorders.[childrenshospital.org] After a reasonably normal early childhood, progressive clumsiness of gait and skeletal deformity (such as scoliosis) are noted, typically with progression to a wheelchair[dartmouth.edu] Early in the disease course: tingling and numbness in arms, legs, trunk, and face visual disturbances: double vision (diplopia); partial blindness weakness and clumsiness[quizlet.com]

  • Proximal Myopathy with Extrapyramidal Signs

    TABLE 3 Functional Organization of Symptoms Associated With ANS Disorders PEDIATRIC AUTONOMIC DISORDERS Many pediatric autonomic disorders are apparent at birth or within[pediatrics.aappublications.org] High serum creatine kinase Increased CPK Increased creatine kinase Increased creatine phosphokinase Increased serum CK Increased serum creatine kinase Increased serum creatine[rarediseases.info.nih.gov] The child then develops a clumsy, waddling gait and pseudohypertrophy of the calf muscles, associated with difficulty climbing stairs and rising from a chair.[intranet.tdmu.edu.ua]

  • Chorea Acanthocytosis Syndrome

    Minerva Pediatr. 1990 Apr. 42(4):151-6. [Medline]. Saiki S, Sakai K, Murata KY, Saiki M, Nakanishi M, Kitagawa Y, et al.[emedicine.medscape.com] Not all have acanthocytes, but most will have increased creatine phosphokinase. The diagnosis is made by looking for the affected protein, chorein.[contact.org.uk] These features can result in clumsiness, gait (walking) problems, difficulty controlling movement, and speech problems.[rarediseases.org]

  • Storage Disease

    Neurology and Muscular Disorders, Istituto Giannina Gaslini, Genoa, Italy. 9 Neuroimmunology and Neuromuscular Diseases Unit, Fondazione IRCCS Istituto Neurologico Carlo[ncbi.nlm.nih.gov] creatine phosphokinase (CPK).[casesjournal.biomedcentral.com] Peripheral neuropathy can present as initial symptoms of gait impairment; stumbling, clumsiness can resemble ataxia.[clinicaladvisor.com]

  • Huntington Disease-Like 3

    […] metabolic disorders (glutaricOther pediatric metabolic disorders (glutaric aciduria)aciduria) 23.[slideshare.net] The disease usually starts in the 20s and progresses slowly over 15 to 30 years. [60] Blood tests reveal elevated levels of creatine phosphokinase in most cases.[movementdisorders.org] At the age of 5 years his speech became progressively incoherent, hand movements became clumsy, and his gait unsteady.[cags.org.ae]