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223 Possible Causes for Clumsy Gait, Pediatric Disorder, Progressive Mental Retardation

  • Hallervorden-Spatz Syndrome

    It is characterized by progressive Parkinson-like rigidity, athetotic movements, and progressive mental and emotional retardation.[whonamedit.com] […] treatments and interventions Covers neurological, neuropsychiatric, and neuromedical disorders across the lifespan (pediatric, adult, and geriatric populations) Includes[books.google.com] Clumsiness, gait disturbance, and difficulty with tasks requiring fine motor coordination are common presenting symptoms. Motor tics are often seen.[disorders.eyes.arizona.edu]

  • Niemann-Pick Disease

    retardation.[icd9data.com] Unit, Department of Pediatrics, Verona, Italy.[ncbi.nlm.nih.gov] , clumsiness, problems in walking (ataxia) Difficulty in posturing of limbs (dystonia) Slurred, irregular speech (dysarthria) Learning difficulties and progressive intellectual[npuk.org]

  • Ataxia Telangiectasia

    In contrast, she showed symptoms not generally related to AT, including microcephaly, profound motor and mental retardation, small hands and feet, severely and progressively[ncbi.nlm.nih.gov] […] all neurosurgical conditions of infants, children and adolescents, with special expertise in the management of pediatric brain tumors, hydrocephalus, spinal cord disorders[massgeneral.org] Although by history there was mild gait clumsiness in early childhood, the leading problem was that of dystonia with onset at age 15, in the absence of gross gait imbalance[ncbi.nlm.nih.gov]

  • Richards-Rundle Syndrome

    progressive spasticity, X-linked, Mental retardation, X-linked, with cerebellar hypoplasia and distinctive facial appearance, Metachromatic Leukodystrophy, Miller Fisher[wikidoc.org] Corticotrophin-releasing hormone type 1 receptor gene (CRHR1) variants predict posttraumatic stress disorder onset and course in pediatric injury patients.[connects.catalyst.harvard.edu] gait.[nature.com]

  • Duchenne Muscular Dystrophy

    Some patients also have mild mental retardation. As DMD progresses, a wheelchair may be needed.[medterms.com] BACKGROUND AND PURPOSE: Duchenne muscular dystrophy (DMD) is a lethal progressive pediatric muscle disorder and genetically inherited as an X-linked disease that caused by[ncbi.nlm.nih.gov] Additional early signs and symptoms include: Developmental delay Muscle weakness Clumsiness Waddling gait Difficulty or inability to perform activities such as climbing stairs[pfizer.com]

  • Rett Syndrome

    The disorder is the most common cause of progressive mental retardation in girls. Parents experience health workers who have not heard about this disorder.[ncbi.nlm.nih.gov] El-Bitar, Degenerative Disorders Primarily of Gray Matter, Swaiman's Pediatric Neurology, 10.1016/B978-1-4377-0435-8.00041-X, (518-543), (2012). Eveline E. O.[doi.org] These mice do not express Mecp2 at all and they display the same symptoms as humans, such as normal development until about 6 weeks, regression, reduced movement, clumsy gait[doi.org]

  • Laurence Moon Syndrome

    Also mental retardation, stunted stature and hypogonadism. Spinocerebellar ataxia and progressive spastic paraplegia are variable components. Onset in childhood.[whonamedit.com] Pediatr Nephrol. 2012 Jan;27(1):7-15.[de.slideshare.net] […] problems and clumsiness Behavioral issues including outbursts, emotional immaturity, etc.[dovemed.com]

  • Mucopolysaccharidosis 2

    The severe form is associated with progressive mental retardation and physical disability, with most individuals dying before age 15.[encyclopedia.com] Abstract Mucopolysaccharidosis type II (MPSII) is an inherited disorder due to a deficiency of the lysosomal enzyme iduronate-2-sulfatase (IDS).[ncbi.nlm.nih.gov] Gait was noted to be clumsy and stiff. Range of motion in all extremities was limited, and the arms and legs were slightly flexed.[amhsr.org]

  • Metachromatic Leukodystrophy

    One of the two un-transplanted controls, 15 years after MLD diagnosis, has relentlessly progressed to full dependency with epilepsy, severe mental retardation, dystonic movements[ncbi.nlm.nih.gov] Neurology , Center for Childhood White Matter Disorders, VU University Medical Center , Amsterdam , The Netherlands 2 Amsterdam Neuroscience , VU University Medical Center[jnnp.bmj.com] Clumsiness, gait problems, slurred speech, incontinence, bizarre behavior and seizures are also observed.[genedx.com]

  • Infantile Hemiplegia

    […] infantile hemiplegia, mental retardation and well-controlled late-onset focal motor seizures and MRI findings characteristic of the rare syndrome known as DDMS with additional[neurologyindia.com] [Crossref] Mak MK (2010) Reaching and grasping a moving target is impaired in children with developmental coordination disorder. Pediatr Phys Ther 22: 384-391.[oatext.com] Ataxic Gait Most commonly seen in cerebellar disease, this gait is described as clumsy, staggering movements with a wide-based gait.[web.archive.org]