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12 Possible Causes for Coagulation Factor Disorder, Fluctuating Level of Consciousness, Lactate Dehydrogenase Increased

  • Acute Alcohol Intoxication

    Patients with a severe liver disorder often have coagulopathy due to decreased hepatic synthesis of coagulation factors, increasing the risk of significant bleeding due to[merckmanuals.com]

  • Myocardial Infarction

    In contrast to the rapid rise and decline of these two enzyme levels, lactate dehydrogenase (LD) levels begin to increase the first day after attack and persist at high levels[medical-dictionary.thefreedictionary.com] factors may play a role in these disorders. 23 A large prospective case-control study found an increased risk of cognitive impairment (OR 1.82) in blood group AB individuals[ncbi.nlm.nih.gov] Enzymes such as glutamine oxaloacetic transaminase (aspartate aminotransferase) and lactate dehydrogenase are still being used for diagnosis of MI in some laboratories.[dx.doi.org]

  • Pulmonary Embolism

    […] cell anemia, congenital coagulation disorders, chest trauma, certain congenital heart defects, and old age.[medical-dictionary.thefreedictionary.com] Risk factors include: prolonged bed rest, surgery, childbirth, heart attack, stroke, congestive heart failure, cancer, obesity, a broken hip or leg, oral contraceptives, sickle[medical-dictionary.thefreedictionary.com]

  • Alcoholic Liver Disease

    […] of consciousness Bloody or dark, black, or tar-like bowel movements Breast development in males Difficulty concentrating Fluctuating mood Hallucinations Impaired judgment[puristat.com] disorders (due to impaired production of coagulation factors), ascites (heavy abdominal swelling due to buildup of fluids in the tissues) and other complications, including[en.wikipedia.org] Fatigue Fever Jaundice Loss of appetite Nausea Weight gain due to ascites Additional symptoms associated with the disease: Abnormally dark or light skin Agitation Altered level[puristat.com]

  • Diabetic Ketoacidosis

    It is characterized by triad of muscle weakness, myalgia and dark urine and is associated with increased creatine kinase and lactate dehydrogenase.[ncbi.nlm.nih.gov] Headache and fluctuating level of consciousness herald this complication in some patients, but respiratory arrest is the initial manifestation in others.[merckmanuals.com] Besides metabolic abnormalities, other risk factors for ischemic stroke in children include congenital heart disease, sickle-cell anemia, coagulation disorders, vasculopathy[dx.doi.org]

  • Thrombotic Thrombocytopenic Purpura

    The hematological changes in vitamin B12 deficiency present as megaloblastic anemia, increased lactate dehydrogenase, vasoconstriction, increased platelet aggregation, and[ncbi.nlm.nih.gov] […] mental status and level of consciousness.[epilepsy.com] Immune System Diseases Thrombophilia Rituximab Antineoplastic Agents, Immunological Antineoplastic Agents Immunologic Factors Physiological Effects of Drugs Antirheumatic[clinicaltrials.gov]

  • Thrombocytopenia

    dehydrogenase and creatine kinase levels, increased serum creatinine, blood urea nitrogen, and C-reactive protein (CRP), hyponatremia, and prolonged activated partial thromboplastin[ncbi.nlm.nih.gov] […] mental status and level of consciousness.[epilepsy.com] […] rates exceed 20 percent; prognosis is based on treating the underlying disorder Drug-induced thrombocytopenia Moderate to severe Can range from asymptomatic to evidence of[aafp.org]

  • Purpura

    Lactate dehydrogenase levels and platelet count are sensitive indicators of the response to therapy.[epilepsy.com] The differential diagnosis to purpura can be divided into platelet disorders, vascular factors and coagulation factor deficiencies.[clinicaladvisor.com] The most commonly encountered disorders are coagulation factor VIII deficiency, coagulation factor IX deficiency and von Willebrand's disease.[aafp.org]

  • Blepharofacioskeletal Syndrome

    Serum lactate is increased in 50% of patients but is less sensitive than CSF lactate.[neuroweb.us] factors deficiency Connective tissue disorder due to lysyl hydroxylase-3 deficiency Continuous spikes and waves during sleep Corneal-cerebellar syndrome Cornelia de Lange[sanfordresearch.org] Neurologic decline persists in stage III (decreased level of consciousness, autonomic instability (with a variable heart rate and widely fluctuating temperatures and blood[neuroweb.us]

  • Familial Dyskinesia and Facial Myokymia

    Serum lactate is increased in 50% of patients but is less sensitive than CSF lactate.[neuroweb.us] […] cells.peptidase S1Clotting Disorders Factor XI triggers the middle phase of the intrinsic pathway of blood coagulation by activating factor IX. kcaFA12Coagulation factor[molsoft.com] Neurologic decline persists in stage III (decreased level of consciousness, autonomic instability (with a variable heart rate and widely fluctuating temperatures and blood[neuroweb.us]