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111 Possible Causes for Coagulation Factor Disorder, Hypoxia, Lactate Dehydrogenase Increased

  • Disseminated Intravascular Coagulation

    Plasma exchange only improved lactate dehydrogenase levels. We clinically diagnosed this case as atypical HUS and started eculizumab treatment.[] […] including transfusion reaction, drug induced hemolysis, and Paroxysmal nocturnal hemoglobinuria Vascular malformation and aneurysms Massive tissue injury (includes trauma) Hypoxia[] coagulation factors.[]

  • Myocardial Infarction

    In contrast to the rapid rise and decline of these two enzyme levels, lactate dehydrogenase (LD) levels begin to increase the first day after attack and persist at high levels[] 10 minutes of hypoxia and a sustained activation that starts after two hours of hypoxia. 113 In this model, ERK2 and JNK are not activated.[] factors may play a role in these disorders. 23 A large prospective case-control study found an increased risk of cognitive impairment (OR 1.82) in blood group AB individuals[]

  • Thalassemia

    At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[] […] and vWF:antigen in patients with NTDT of beta-thalassemia genotype, and correlated them with erythrocytic indices and markers of iron overload, inflammation, and tissue hypoxia[] Marrow expansion, chronic hypoxia, endocrine complications, and iron overload caused chiefly by chronic transfusion treatment are significant factors affecting skeletal health[]

  • Pulmonary Embolism

    Hypoxia is an independent predictor of both right ventricular dysfunction and 30-day mortality in these patients.[] […] cell anemia, congenital coagulation disorders, chest trauma, certain congenital heart defects, and old age.[] CONCLUSIONS Tracheobronchomalacia should be considered in the differential diagnosis of hypoxia when evaluating a patient in the ICU.[]

  • Sickle Cell Disease

    We show that ( i ) hypoxia significantly enhances sickle RBC adherence; ( ii ) HbS polymerization enhances sickle cell adherence in SRs and SMEs, but not in ISCs; ( iii )[] Keywords: sickle cell, hemolysis, coagulation, tissue factor, inflammation Introduction Sickle cell anemia is the most common and severe variant of sickle cell disease.[] We present the unusual case of complete neurologic survival after prolonged hypoxia, severe acidosis, out of hospital cardiac arrest, and exposure to high levels of carbon[]

  • Myxedema

    Elevated lactate dehydrogenase concentrations, acidosis, and anemia are common findings. Lumbar puncture reveals increased opening pressure and high protein content.[] Pulmonary The main pulmonary effect of myxedema coma is hypoventilation, which results from central depression of ventilatory drive with decreased responsiveness to hypoxia[] Among the hematologic disorders, normocytic and normochromic anemia, von Willebrand disease, reduction in factors V, VII, VIII, IX and X production, decrease of granulocytes[]

  • Acute Alcohol Intoxication

    Medical and traumatic causes such as hypoglycemia, stroke, hypothermia, hypoxia, drug overdose, head trauma and other causes have serious consequences if not identified, managed[] Patients with a severe liver disorder often have coagulopathy due to decreased hepatic synthesis of coagulation factors, increasing the risk of significant bleeding due to[]

  • Hemoglobin SC Disease

    These crises are usually brought on by stressors that induce hypothermia, hypoxia or acidosis, such as surgery [1].[] Since nearly every component of hemostasis is altered in the direction of a pro-coagulant phenotype in SCD, this disorder has been referred to as a “hypercoagulability state[] The fluorescein angiographic findings in our case provide further support for the hypothesis that retinal hypoxia is an important stimulus for retinal neovascularization.[]

  • Red Blood Cell Disorder

    The client is taught to avoid specific activities that lead to hypoxia and hypoxemia.[] Renal hypoxia may promote an increase in erythropoietin production.[] Hemostasis Disorders The most common blood disorders involve defects in the amount or activity of factors involved in coagulation.[]

  • Pulmonary Infarction

    Pulmonary embolism and myocardial hypoxia during extracorporeal membrane oxygenation. J Pediatr Surg. 1999 Mar. 34(3):485-7. [Medline]. Kossoff EH, Poirier MP.[] Coagulation disorders: Conditions such as deficiency of protein S or C and antithrombin III deficiency.[] […] ectopic, occult trauma) Basics: ABCs, IV, O 2 , Cardiac Monitor and 12-lead EKG Airway, Breathing Circulation Intubation may be necessary if the patient has significant hypoxia[]

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