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104 Possible Causes for Coagulation Factor Disorder, Jaundice, Lactate Dehydrogenase Increased

  • Thalassemia

    Diagnostic methods Diagnosis is suspected in infants younger than 2 years of age with severe microcytic anemia, mild jaundice and hepatosplenomegaly.[orpha.net] At the end of the treatment period, Hb and HbF increased by 2.5   1.8 g/dL and 2.5   1.6 g/dL, while bilirubin, lactate dehydrogenase, and the nucleated red blood cell count[ncbi.nlm.nih.gov] Clinical description Patients present with moderate to severe anemia, jaundice and splenomegaly.[orpha.net]

  • Alcoholic Liver Disease

    The term acute alcoholic cholestasis is suggested for this apparently distinct syndrome of cholestatic jaundice in the absence of hepatitis.[ncbi.nlm.nih.gov] disorders (due to impaired production of coagulation factors), ascites (heavy abdominal swelling due to buildup of fluids in the tissues) and other complications, including[en.wikipedia.org] The diagnosis of Zieve syndrome was confirmed based on hemolysis and cholestatic jaundice secondary to alcoholic liver disease and heavy drinking.[ncbi.nlm.nih.gov]

  • Macronodular Cirrhosis

    List 3 causes of pre-hepatic jaundice List 2 causes of post-hepatic jaundice. List 3 causes of hepatic jaundice.[quizlet.com] Prothrombin time (PT) is elevated due to coagulation factor defects as well as bilirubin, while albumin is low as it is synthesized by the liver and the liver's functional[ncbi.nlm.nih.gov] Pruritus is reported when significant jaundice is present.[medical-dictionary.thefreedictionary.com]

  • Autoimmune Hemolytic Anemia

    Secondary AIHA might not be diagnosed appropriately because the obstructive jaundice observed in type 1 AIP/IgG4-SC can obscure the presence of hemolytic jaundice.[ncbi.nlm.nih.gov] Unconjugated bilirubin is usually, but not always, elevated and urine urobilinogen is increased. Lactate dehydrogenase is usually elevated into the thousands.[clinlabnavigator.com] Epidemiology Risk factors are variable and depend on the underlying cause.[patient.info]

  • Cooley's Anemia

    Children develop life-threatening anemia, have failure to thrive, and may develop jaundice.[secure.ssa.gov] […] and a decreasing trend in the serum lactate dehydrogenase (LDH) and serum unconjugated bilirubin levels.[onlinelibrary.wiley.com] The Coagulation Factors site features articles and news on coagulation disorders, and also includes a health directory and information on clinical trials for coagulation disorder[nhoh.com]

  • Myxedema

    Infants with hypothyroid will present with jaundice, protruding tongue, frequent choking, puffy face, poor muscle tone, constipation, and excessive sleepiness.[symptoma.com] Elevated lactate dehydrogenase concentrations, acidosis, and anemia are common findings. Lumbar puncture reveals increased opening pressure and high protein content.[endocrinologyadvisor.com] Among the hematologic disorders, normocytic and normochromic anemia, von Willebrand disease, reduction in factors V, VII, VIII, IX and X production, decrease of granulocytes[jscimedcentral.com]

  • Sickle Cell Disease

    Jaundice, or yellowing of the skin, eyes, and mouth. Jaundice is a common sign and symptom of sickle disease.[hopkinsmedicine.org] Keywords: sickle cell, hemolysis, coagulation, tissue factor, inflammation Introduction Sickle cell anemia is the most common and severe variant of sickle cell disease.[ncbi.nlm.nih.gov] Early symptoms of SCD may include Painful swelling of the hands and feet Fatigue or fussiness from anemia A yellowish color of the skin ( jaundice ) or the whites of the eyes[nlm.nih.gov]

  • Microangiopathic Hemolytic Anemia

    A newborn infant with a large hepatic hemangioma developed congestive heart failure, consumption coagulopathy, microangiopathic hemolytic anemia, and obstructive jaundice.[ncbi.nlm.nih.gov] Laboratory abnormalities Anemia Increased lactate dehydrogenase. Increased indirect bilirubin. Decreased haptoglobin. Increased urine urobilinogen.[clinicaladvisor.com] […] extensive burn, brain injury Other: Obstetric disorders; snakebite; vascular disorders; hemolysis Pathogenesis Tissue factor or bacterial toxin activates coagulation cascade[basicmedicalkey.com]

  • Nonimmune Hemolysis

    Dehydrogenase Deficiency in A Geriatric Patient The Editor, Sir, An otherwise healthy 76 years old female patient presented to emergency department with acute fatigue, weakness and jaundice[mona.uwi.edu] Increased serum unconjugated bilirubin, increased lactate dehydrogenase (LDH) and reduced or absent haptoglobin. Increased urinary urobilinogen, haemosiderinuria.[patient.info] Symptoms Symptoms may include any of the following: Dark urine Fatigue Pale skin color Rapid heart rate Shortness of breath Yellow skin and whites of the eyes ( jaundice )[ufhealth.org]

  • Acquired Toxic Hemolytic Anemia

    […] hemolytic anemia Caused by external factors red blood cells are normal What is extrinsic hemolytic anemia What organ is a primary side of destruction of red blood cells Jaundice[quizlet.com] Breakdown of RBCs releases lactate dehydrogenase and potassium, leading to elevation of both in serum.[accessmedicine.mhmedical.com] Disseminated Intravascular Coagulation Hypercoagulable States The Antiphospholipid Syndrome Venous Thromboembolism Mechanical Interventions in Arterial and Venous Thrombosis[libreriacortinamilano.it]

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