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284 Possible Causes for Coarse Facial Features, Coronary Artery Disease

  • Mucopolysaccharidosis

    Severe coronary artery disease is well recognized in severe type I mucopolysaccharidosis (Hurler syndrome), but unexpected coronary artery disease occurs in other, "non-Hurler[] facial features, developmental delay, and an elevated quantitative urine glycosaminoglycan (GAG) level.[] The patient had severe infantile global neurodevelopmental delays, macrocephaly with a prominent forehead, coarse facial features with clear corneas, chronic congestion with[]

  • Fabry Disease

    , ventricular tachycardia, atrial fibrillation and coronary artery disease).[] Often patients have slight builds with characteristic coarse facial features and delayed puberty.[] The patient is 10 years old and presents severe mental handicap, coarse face, hepatosplenomeagly, dysostosis multiplex, joint contractures, obstructive airway disease, mitral[]

  • Mucopolysaccharidosis 2

    Other symptoms may include carpal tunnel syndrome, coarse facial features, deafness, hairy body (hypertrichosis), joint stiffness, and a large head (macrocephaly).[] A thickened myocardium eventually leads to coronary artery compromise, myocardial disease, and, in conjunction with airway disease, pulmonary hypertension.[] There are some obvious physical signs of Hunter syndrome, such as coarse facial features and an enlarged liver and spleen, as well as some less noticeable symptoms. 2 Symptoms[]

  • Mucopolysaccharidosis 1

    Further common findings are coarse facial features, carpal tunnel syndrome, umbilical and inguinal hernia, and hepatomegaly.[] Caution should be exercised if epinephrine is being considered for use in patients with MPS I due to the increased prevalence of coronary artery disease in these patients.[] Cardiomyopathy and coronary heart disease. Hepatosplenomegaly.[]

  • Mucopolysaccharidosis 1H

    : early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent perivascular spaces[] […] hairy skin all over the body, a tuft of hair in the parietal region, coarse facial features and a prominent forehead with a large tongue, hepatosplenomegaly and skeletal[] Joint stiffness and skeletal deformities Coronary heart disease. Hepatosplenomegaly. Diagnosis: Exams and Tests: Electrocardiogram (EKG).[]

  • Chronic Alcoholism

    Light-to-moderate alcohol intake is associated with a decreased incidence of coronary heart disease, while heavy drinking may be a precursor for cardiomyopathy.[] Heart attacks and angina [chest pain] are the most common results of coronary heart disease. Someone has a heart attack when their coronary arteries become blocked.[] Coronary heart disease is the most common type of heart disease and can lead to sudden death from a heart attack.[]

  • Sick Sinus Syndrome

    A 62-year-old woman had acromegaly and developed congestive heart failure with cardiomyopathy, mitral regurgitation due to chordae rupture, coronary artery disease and sick[] facial features that become more prominent with age.[] If a patient is on a class 1C antiarrhythmic drug and develops coronary artery disease, the drug should be discontinued.[]

  • Juvenile Myxedema

    Hyperlipidemia Coronary artery disease Hypertension Neonatal/congenital hypothyroidism Prolonged jaundice Hoarse cry Constipation Somnolence Feeding problems Impaired mental[] In elderly patients with history of coronary artery disease the full replacement dose should not be immediately administered.[] Levothyroxine sodium should be used with caution in patients with cardiovascular disorders, including angina, coronary artery disease, hypertension, and in the elderly who[]

  • Acromegaly

    Most deaths result from heart failure, coronary artery disease and hypertension-related causes.[] A 30-year-old Filipino man presented with a 11-year history of coarse facial features and progressive enlargement of hands and feet.[] Deaths in the patient group Deaths in the general population Cause of death n % 95% CI n % 95% CI P Cardiovascular diseases 38 34 442 33 0.92 Coronary artery disease 26 23[]

  • Dilated Cardiomyopathy

    It is characterized by coarse facial features, developmental delay, short stature, and skeletal deformities.[] This effect was observed even in the presence of concomitant coronary artery disease.[] […] cardiomyopathy (A term used when coronary heart disease , also called coronary artery disease or heart attack cause the disease.[]

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