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295 Possible Causes for Coarse Facial Features, Coronary Artery Disease, Frontal Bossing

  • Mucopolysaccharidosis

    facial features, developmental delay, and an elevated quantitative urine glycosaminoglycan (GAG) level.[ncbi.nlm.nih.gov] bossing.[invitae.com] Severe coronary artery disease is well recognized in severe type I mucopolysaccharidosis (Hurler syndrome), but unexpected coronary artery disease occurs in other, "non-Hurler[ncbi.nlm.nih.gov]

  • Acromegaly

    Most deaths result from heart failure, coronary artery disease and hypertension-related causes.[myvmc.com] The forehead and overlying skin is thickened, sometimes leading to frontal bossing.[orpha.net] A 30-year-old Filipino man presented with a 11-year history of coarse facial features and progressive enlargement of hands and feet.[ncbi.nlm.nih.gov]

  • Mucopolysaccharidosis 1

    Systems Cardiology Cardiac involvement includes cardiomyopathy, endocardiofibroelastosis, progressive valvular disease, and coronary artery disease.[medicalhomeportal.org] On examination, child had dysmorphic features such as frontal bossing, hypertelorism, saddle nose, low-set ears, macroglossia, short stature, short neck, kyphosis of lumbar[jcor.in] Further common findings are coarse facial features, carpal tunnel syndrome, umbilical and inguinal hernia, and hepatomegaly.[symptoma.com]

  • Mucopolysaccharidosis 2

    A thickened myocardium eventually leads to coronary artery compromise, myocardial disease, and, in conjunction with airway disease, pulmonary hypertension.[emedicine.medscape.com] Anteroposterior and lateral X-rays of the skull showed an calvarial thickening and depressed bridge of nose with frontal bossing with hypopneumatised mastoid ( Figure 3 ).[omicsonline.org] Other symptoms may include carpal tunnel syndrome, coarse facial features, deafness, hairy body (hypertrichosis), joint stiffness, and a large head (macrocephaly).[secure.ssa.gov]

  • Launois Syndrome

    , coronary artery disease, insulin-resistance diabetes, depression, and, as mentioned, sleepiness-related accidents.[emedicine.medscape.com] […] for physicians to consider because of its strong association with and potential cause of the most debilitating medical conditions, including hypertension, cardiovascular disease[emedicine.medscape.com]

  • Alpha-Mannosidosis

    Clinical symptoms include coarse facial features, skeletal involvement (dysostosis multiplex), hearing disabilities, mental retardation and hepatosplenomegaly.[ncbi.nlm.nih.gov] For Cardiovascular Group: Either have coronary artery disease, rhythm or conduction abnormality, cardiomyopathy or valvular disease.[rarediseasesnetwork.org] facial features, dysostosis multiplex, hearing disabilities, mental developmental delay and skeletal involvement (dysostosis multiplex).[ncbi.nlm.nih.gov]

  • Gigantism

    Cardiac disease (eg, coronary artery disease, cardiomegaly, sometimes cardiomyopathy) occurs in perhaps one third of patients, with a doubling in the risk of death from cardiac[merckmanuals.com] Other symptoms include: Delayed puberty Double vision or difficulty with side (peripheral) vision Very prominent forehead ( frontal bossing ) and a prominent jaw Gaps between[nlm.nih.gov] Children with gigantism may also have coarse facial features which include a larger than normal head, flat nose, and large lips and tongue.[symptoma.com]

  • Atkin Syndrome

    Insulin resistance-related factors, but not glycemia, predict coronary artery disease in type 1 diabetes: 10 year follow-up data from the Pittsburg Epidemiology of Diabetes[revespcardiol.org] bossing 0002007 Genu recurvatum Back knee Knee hyperextension [ more ] 0002816 Genu valgum Knock knees 0002857 Heavy supraorbital ridges Heavy brow of the face 0002054 Intellectual[rarediseases.info.nih.gov] Abstract We report two sisters with mental retardation, coarse facial features, telecanthus, flat malar region, prominent lower lip, kyphoscoliosis, and tapering fingers.[ncbi.nlm.nih.gov]

  • Mucopolysaccharidosis 1H

    : early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent perivascular spaces[radiopaedia.org] Head is enlarged with frontal bossing and scaphocephalic skull due to premature closure of cranial sutures. A large mouth with thick lips may also be present.[symptoma.com] Note his coarse facial features, crouched stance, thickened digits, and protuberant abdomen. Transgenic mice with a targeted disruption of a -L-iduronidase .[medgen.genetics.utah.edu]

  • Winchester Syndrome

    […] sclerosis of infancy , see generalized arterial calcification of infancy median facial cleft syndrome , see frontonasal dysplasia Mediterranean anemia , see beta thalassemia[herenciageneticayenfermedad.blogspot.com] bossing / prominent forehead - Hirsutism / hypertrichosis / Increased body hair - Irregular / in bands / reticular skin hyperpigmentation - Long / large / bulbous nose -[csbg.cnb.csic.es] Affiliated tissues include bone , skin and testes , and related phenotypes are gingival overgrowth and coarse facial features OMIM : 57 Winchester syndrome presents with severe[malacards.org]

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