Create issue ticket

83 Possible Causes for Coarse Facial Features, Coronary Artery Disease, Short Stature in Children

  • Mucopolysaccharidosis

    Severe coronary artery disease is well recognized in severe type I mucopolysaccharidosis (Hurler syndrome), but unexpected coronary artery disease occurs in other, "non-Hurler[ncbi.nlm.nih.gov] facial features, developmental delay, and an elevated quantitative urine glycosaminoglycan (GAG) level.[ncbi.nlm.nih.gov] Many children develop a short body trunk and a maximum stature of less than 4 feet.[en.wikipedia.org]

  • Mucopolysaccharidosis 2

    A thickened myocardium eventually leads to coronary artery compromise, myocardial disease, and, in conjunction with airway disease, pulmonary hypertension.[emedicine.medscape.com] Other symptoms may include carpal tunnel syndrome, coarse facial features, deafness, hairy body (hypertrichosis), joint stiffness, and a large head (macrocephaly).[secure.ssa.gov] The signs and symptoms may include abnormal facial features, cloudy corneas, abnormal development of spine, heart valve defects, and short stature in children A healthcare[dovemed.com]

  • Mucopolysaccharidosis 1

    Caution should be exercised if epinephrine is being considered for use in patients with MPS I due to the increased prevalence of coronary artery disease in these patients.[aldurazyme.com] Further common findings are coarse facial features, carpal tunnel syndrome, umbilical and inguinal hernia, and hepatomegaly.[symptoma.com] Corneal clouding and cognitive impairment develop, as well as cessation of growth, causing short stature. Joint stiffness and contractures limit mobility.[patient.info]

  • Mucopolysaccharidosis 1H

    […] hairy skin all over the body, a tuft of hair in the parietal region, coarse facial features and a prominent forehead with a large tongue, hepatosplenomegaly and skeletal[dx.doi.org] Affected children have a short stature and suffer from hepatosplenomegaly, a condition characterized by an enlarged liver and spleen.[patienthelp.org] : early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent perivascular spaces[radiopaedia.org]

  • Mucopolysaccharidosis 1S

    Individuals with MPS disorders share many similar symptoms such as multiple organ involvement, distinctive “coarsefacial features, and abnormalities of the skeleton especially[rarediseases.org] facial features, inguinal hernia, umbilical hernia, multiple dysostosis, hepatosplenomegaly and difficulty in breathing; surgical history: right inguinal herniorrhaphy, umbilical[revistamedicina.net] Symptoms usually become apparent between three and eight years of age and include coarse facial features, corneal clouding, joint stiffness, short stature and hepatosplenomegaly[news-medical.net]

  • Juvenile Myxedema

    Hyperlipidemia Coronary artery disease Hypertension Neonatal/congenital hypothyroidism Prolonged jaundice Hoarse cry Constipation Somnolence Feeding problems Impaired mental[quizlet.com] Abstract A FREQUENT presenting sign of hypothyroidism in children is short stature.[mdedge.com] Not all children with short stature have GH deficiency. In most instances, the cause is either familial short stature or constitutional growth delay.[nursekey.com]

  • Williams Syndrome

    We present the case of an 11-month-old infant affected by WS who developed severe coronary artery disease 2 months after the surgical repair of supravalvular aortic stenosis[ncbi.nlm.nih.gov] She had hypotonia and large tongue, "coarse" face, and umbilical hernia in presence of complex congenital cardiovascular malformations.[ncbi.nlm.nih.gov] Low Birth Weight/Short Stature Most children with WS are born with low birth weight and experience slow weight gain during their toddler years.[smartspeechtherapy.com]

  • Pseudo-Hurler Polydystrophy

    These patients usually have skeletal abnormalities, coarse facial features, short height, corneal clouding, carpal tunnel syndrome, aortic valve disease and mild enlargement[en.wikipedia.org] Individuals with mucolipidosis III alpha/beta grow slowly and have short stature.[ismrd.org] : early onset severe regurgitation and stenosis coronary artery disease cardiomegaly: initially hypertrophic then dilated Other features include prominent perivascular spaces[radiopaedia.org]

  • Mucopolysaccharidosis 4A

    He had no risk factors for coronary artery disease, his 12-lead ECG showed a normal sinus rhythm with no Q waves, and there were no elevations in serum creatine kinase-MB,[circ.ahajournals.org] facial features Coarse facial appearance 0000280 Constricted iliac wings 0003277 Coxa valga 0002673 Disproportionate short-trunk short stature Disproportionate short-trunked[rarediseases.info.nih.gov] Many children develop a short body trunk and a maximum stature of less than 4 feet.[en.wikipedia.org]

  • Hypothyroidism

    However, treatment should be initiated at a low dose in elderly patients, patients with coronary artery disease and patients with long-standing severe hypothyroidism.[ncbi.nlm.nih.gov] Other findings may include pale, yellow skin, thin and brittle hair, coarse facial features, brittle nails, firm swelling of the arms and legs, and mental slowing.[uclahealth.org] […] with short stature or chronic diseases, discordant effects on thyroid volume reduction, and no effects on neurocognitive function.[ncbi.nlm.nih.gov]

Similar symptoms