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239 Possible Causes for Coarse Facial Features, Hoarseness, Sleep Disturbance

  • Chronic Alcoholism

    disturbances). [9] Ferenci P, Lockwood A, Mullen K, et al.[] Alcohol also causes sleep disturbances, so sleep quality is diminished. Numbness and tingling (parethesia) may occur in the arms and legs.[] […] includes cognitive deficits, which impact negatively on social and occupational functioning, and persistent non-cognitive abnormalities (such as extrapyramidal alterations or sleep[]

  • Mucopolysaccharidosis

    facial features, developmental delay, and an elevated quantitative urine glycosaminoglycan (GAG) level.[] We describe 2 children with mucopolysaccharidosis (MPS) who were referred for significant sleep disturbance.[] Vocal cords can also enlarge, resulting in a deep, hoarse voice.[]

  • Mucopolysaccharidosis 1

    Vocal cords can also enlarge, resulting in a deep, hoarse voice.[] Further common findings are coarse facial features, carpal tunnel syndrome, umbilical and inguinal hernia, and hepatomegaly.[] In general, symptoms may include coarse facies, short stature, enlarged liver and spleen, hoarse voice, stiff joints, cardiac disease, but no neurological involvement.[]

  • Mucopolysaccharidosis 2

    Common signs and symptoms include a large head, full lips, large rounded cheeks, a broad nose, hoarse voice and an enlarged tongue (macroglossia).[] Other symptoms may include carpal tunnel syndrome, coarse facial features, deafness, hairy body (hypertrichosis), joint stiffness, and a large head (macrocephaly).[] Reported sleep disturbances include difficulty initiating or maintaining sleep, decreased rapid eye movement sleep and sleep onset insomnia. 15,17 Seizures and seizure-like[]

  • Acromegaly

    Ultimately they cause considerable disability (aside from the need for larger rings, gloves, and shoes) including hoarseness , sleep apnea , joint pain, cardiovascular disease[] A 30-year-old Filipino man presented with a 11-year history of coarse facial features and progressive enlargement of hands and feet.[] Sometimes, the first symptoms of acromegaly are tiredness and sleep disturbance.[]

  • Congenital Hypothyroidism

    The child may also have: Poor feeding, choking episodes Constipation Dry, brittle hair Hoarse cry Jaundice (skin and whites of the eyes look yellow) Lack of muscle tone ([] The symptoms of congenital hypothyroidism may include the following: Puffy face Coarse facial features Dull look Thick protruding tongue Poor feeding Choking episodes Constipation[] After thyroxine treatment, she also had headache, vomiting, and palpitation, lack of appetite, and sleep disturbance.[]

  • Hypothyroidism

    Hypothyroidism symptomatology was similar in both groups, except for a greater frequency of hoarseness in the group with HAH.[] Other findings may include pale, yellow skin, thin and brittle hair, coarse facial features, brittle nails, firm swelling of the arms and legs, and mental slowing.[] Women can present with galactorrhea and menstrual disturbances.[]

  • Juvenile Myxedema

    Symptoms of this rare but potentially deadly complication include enlarged tongue, swollen facial features, hoarseness, and physical and mental sluggishness.[] sleep pattern.[] […] consumption of goitrogens (e.g. cassava) Symptoms of hypothyroidism Tiredness, weakness Dry skin Feeling cold Hair loss Constipation Weight gain with poor appetite Dyspnea Hoarse[]

  • Aspartylglucosaminuria

    In some, the voice becomes hoarse.[] facial features, and skeletal abnormalities become evident by adolescence.[] Abstract Sleep disturbances are common in many progressive metabolic encephalopathies.[]

  • Mucopolysaccharidosis 4

    […] deformity, dorsolumbar kyphosis, increased anteroposterior diameter of chest, pectus excarinatum, waddling gait, pot belly, valgus deformity of both upper and lower limbs and hoarse[] Patients may also have coarse facial features, although this is usually milder than that seen in MPSI or MPSII.[] This disease is characterized by severe behavioral disturbances, including hyperactivity, sleep disturbances and destructive behavior.[]

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