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180 Possible Causes for Cognitive Defect, Cortical Thinning

  • Alzheimer Disease

    Na, Dae Ryong Kang and Sang Won Seo, Higher education affects accelerated cortical thinning in Alzheimer's disease: a 5-year preliminary longitudinal study, International[dx.doi.org] Case Western Reserve researchers discover FDA-approved drug rapidly clears amyloid from the brain and reverses cognitive defects.[neurosciencenews.com] ., posterior cingulate, precuneus, and/or temporoparietal cortices) on FDG-PET, and (3) cortical thinning/gray matter loss in a specific anatomic distribution (i.e., lateral[ncbi.nlm.nih.gov]

  • Traumatic Brain Injury

    Blast-Exposed Veterans With Mild Traumatic Brain Injury Show Greater Frontal Cortical Thinning and Poorer Executive Functioning .[doi.org] These may include motor dysfunction (paralysis, balance or gait abnormalities), cognitive impairment (amnesia, disorientation, confusion), speech defects (aphasia, dysphasia[symptoma.com]

  • Obstructive Sleep Apnea

    We used high-resolution magnetic resonance imaging to identify OSA-related cortical thinning, based on a model with condition and sex as independent variables.[ncbi.nlm.nih.gov] […] exposure in OSA, although disease comordities may also contribute to thinning.[ncbi.nlm.nih.gov] The greater cortical injury in cognitive areas of female OSA patients may underlie enhanced symptoms in that group.[ncbi.nlm.nih.gov]

  • Multi-Infarct Dementia

    Incident subcortical infarcts induce focal thinning in connected cortical regions. Neurology. 2012;79(20):2025–8.[doi.org] […] impairment due to ASHD-induced disease; MID is more common in and associated with DM, HTN, smoking, amyloidosis Clinical Gait and motor defects, defects of language, mood[medical-dictionary.thefreedictionary.com] […] provide important information Cardiac auscultation: Cardiac rhythmic and valvular abnormalities may be detected Neurologic assessment: Spasticity, hemiparesis, visual field defects[emedicine.com]

  • Adult Attention Deficit Disorder

    Cortical thinning of the attention and executive function networks in adults with attention-deficit/hyperactivity disorder.[ncbi.nlm.nih.gov] AADD is usually characterized by symptoms of behavioral and cognitive change which include hyperactivity, absent-mindedness, impulsiveness, and disorganization.[symptoma.com] Slower cortical thinning during adolescence is characteristic of ADHD and provides neurobiological evidence for dimensionality.[emedicine.com]

  • Multiple Sclerosis

    thinning in patients with obstructive sleep apnea syndrome, Sleep, 2013 , vol. 36 (pg. 1153 - 62 ) 32 Deficits in memory and visuospatial learning correlate with regional[dx.doi.org] ), lack of coordination, tremor, incontinence and cognitive impairment [ 1, 2 ].[dx.doi.org] Compared with WM, GM atrophy is more strongly associated with disease progression. 11 Atrophy in deep GM structures begins very early in the disease, and cortical thinning[doi.org]

  • Dialysis Dementia

    […] rus atroph ies # "ch4.arri, et al, 2 010 &, whole brain and hippo campus atrop hies # enneman, et al, 200( &3 cortical thinning # *abuncu, et al, 2001 &, hippocampus .olume[scribd.com]

  • Leigh's Disease

    […] nigro-cortical tracts ( thin arrow ).[ajnr.org] Abnormality of cognition Cognitive abnormality Cognitive defects Cognitive deficits Intellectual impairment Mental impairment More information about the genes responsible[rarediseases.info.nih.gov] Treatment: See Beta-oxidation Defects . Links: OMIM Long Name: Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes.[umdf.org]

  • Dementia with Lewy Bodies

    RESULTS: Dementia with Lewy bodies, AD and control participants showed significantly different hippocampal, parahippocampal and entorhinal cortical thinning, where atrophy[ncbi.nlm.nih.gov] defects in DLB.[ncbi.nlm.nih.gov] Amyloid-β associated cortical thinning in clinically normal elderly. Ann. Neurol. 69, 1032–1042 (2011). 117.[doi.org]

  • Lupus Cerebritis

    Both SLE and NPSLE groups exhibited comparable thinning in frontal and temporal lobes 71 .[f1000research.com] These antibodies also correlate with cognitive and visual spatial defects. Second, the anti-neuronal membrane antibodies are targeted directly to neuronal antigens.[en.wikipedia.org] The NPSLE group exhibited decreased cortical thickness in left frontal and parietal lobes as well as in right parietal and occipital lobes compared to controls.[f1000research.com]

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