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10 Possible Causes for Cognitive Defect, EEG Generalized Slowing, Episodic Blurred Vision

  • Hypoglycemia

    vision Headache Trouble performing routine tasks Note: Symptoms can vary from person to person and episode to episode.[] Symptoms of Hypoglycemia Symptoms of hypoglycemia include the following: Sweating Rapid pulse Shakiness, dizziness, weakness Decreased coordination Difficulty concentrating Blurred[]

  • Stroke

    CONCLUSIONS: Abnormal EEG in general and generalized slowing in particular are associated with clinical deterioration after acute ischemic stroke.[] He developed headache, nausea, vomiting, blurred vision, diplopia, dizziness, and ataxia following the procedure.[] Background The background EEG may be normal or show focal slowing over the location of the stroke.[]

  • CADASIL Syndrome

    Electroencephalograms (EEGs) were performed in five patients and showed generalized slowing.[] vision in late adolescence.[] In the vast majority of cases, patients affected patients will present with ischemic episodes, cognitive defects, migraine like headaches or psychiatric disturbances.[]

  • Episodic Ataxia

    Fig. 2 EEG of case III2 during complex partial epileptic seizure. Right temporal sharp and slow waves generalize to involve the right hemisphere.[] During episodes, many of those affected manifest dizziness, nausea, vomiting, headaches, blurred or double vision, dyslexia and tinnitus.[] Affected individuals present with features of cerebellar ataxia, seizures, cognitive impairment, and peripheral neuropathy.[]

  • Autosomal Dominant Mental Retardation 28

    Acetazolamide & Phenytoin Cognition: Impaired Laboratory EEG: Generalized slowing CSF Glucose & Lactate: Low Hypomyelinating Leukodystrophy 6 (HLD6; HABC) Sporadic, ?[] vision, diplopia, choking episodes, limb weakness Chronic bronchitis Axonal sensorimotor polyneuropathy / / / / / / / / / / / / Dysphagia Proximal weakness Atrial hypertrophy[] defects, and facial dyskinesia, and Friedreich ataxia variant [ 2 ].[]

  • Spastic Ataxia with Congenital Miosis

    By 13 months, EEG showed features of West syndrome, hypsarrhythmia, and generalized slowing, consistent with a diffuse encephalopathic process.[] During these episodes, many people also experience dizziness (vertigo), nausea and vomiting, migraine headaches, blurred or double vision, slurred speech, and ringing in the[] X-linked Disorders: Dominant - Heterozygous males and females are affected - Reduced penetrance in females - Fragile X Syndrome is an Example: Most common genetic cause of cognitive[]

  • Epilepsia Partialis Continua

    Case A 58 year-old man presented with weakness, blurred vision, polydipsia, polyuria and shaking of the left leg for 4 days.[] EEG background abnormalities showed generalized slowing in 45 patients (78.9%) and focal slowing in two patients (3.5%).[] Most patients will continue with intractable epilepsia partialis continua and also develop neurologic and cognitive defects. Only a few patients may have a remission.[]

  • Autosomal Dominant Mental Retardation 24

    In our samples, we did not find a slowing down nor any frequency-specific EEG changes [5]; furthermore, we did not find any anomalies such as generalized or multifocal spike[] vision, diplopia, choking episodes, limb weakness Chronic bronchitis Axonal sensorimotor polyneuropathy / / / / / / / / / / / / Dysphagia Proximal weakness Atrial hypertrophy[] Cognitive defects are present in 30% of patients and some individuals have been described as mentally retarded.[]

  • Lethal Neonatal Spasticity - Epileptic Encephalopathy Syndrome

    Cognitive deficits Abnormal imaging in 2/3, cryptogenic in 1/3 EEG findings: Slow generalized spike-and-wave discharges (1-2 Hz) AEDs of choice: Valproate, clonazepam, ethosuximide[] Leber hereditary optic neuropathy (blurring, loss of central vision) 2. MERRF (myoclonic epilepsy, ragged red fibers) 3.[] Treatment: See Beta-oxidation Defects . Links: OMIM Long Name: Mitochondrial Encephalomyopathy Lactic Acidosis and Strokelike Episodes.[]

  • Spastic Paraplegia - Ataxia - Mental Retardation

    This rapid increase of ammonia may lead to episodes of vomiting, lack of energy (lethargy), problems with coordination (ataxia), confusion, or blurred vision.[] The EEG exhibits periodic complexes with generalized bilateral, usually synchronous and symmetrical sharp and slow wave complexes of high amplitude (greater than 500 uV),[] […] neuropathy, and deafness. [4] HSP is caused by defects in the mechanisms that transport proteins and other substances through the cell.[]

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