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23 Possible Causes for Cognitive Defect, Hyperintensities in the Globus Pallidus (T2-Weighted)

Did you mean: Cognitive Defect, Hyperintensities in the Globus Pallidus (T2-Weighted

  • Binswanger Disease

    The bilateral cerebral white matter and globus pallidus appeared hyperintense on T2-weighted imaging (Figures 5 and 6). 5) Figure 5. CO poisoning(FLAIR image) Figure 6.[plaza.umin.ac.jp] These cases can be distinguished from general paralysis first by the stability of their deficits, secondly by the peculiar development of the cognitive defect (decrease of[www2.psykl.med.tum.de] This type of injury will not typically result in defects of multiple cognitive domains, as occur in dementia.[aafp.org]

  • Wernicke Encephalopathy

    […] in the globus pallidus.[ncbi.nlm.nih.gov] Retentive memory is impaired out of proportion to other cognitive functions in the otherwise alert and responsive patient.[clinicaladvisor.com] T1-weighted MR image depicts symmetric hyperintense foci in the globus pallidus (arrows).[doi.org]

  • Creutzfeldt Jakob Disease

    Extrapontine myelinolysis manifests predominantly as areas of bilateral FLAIR /T2-weighted imaging hyperintensity in the globus pallidus, putamen, and thalamus, which are[doi.org] For sCJDMV1 patients, ataxia rather than cognitive decline as well as sensory defect may be more common at onset.[doi.org] MR imaging abnormalities consist primarily of restricted hyperintensity in the striatum on diffusion-weighted and FLAIR /T2-weighted images ( Fig 20 ), with a peculiar anteroposterior[doi.org]

  • Wilson Disease

    On T1W images, these lesions are normal to hypointense but hyperintense lesions especially in globus pallidus may also be seen [ 2 ].[omcr.oxfordjournals.org] The lesions showed no signal-intensity abnormality on T2-weighted images. The cause of hyperintensity in T1-weighted images remains elusive.[ajnr.org] Figure 1: MRI brain T2-weighted image shows abnormal hyperintensity in pons with characteristic hypointense ‘trident’ sign ( A ) and characteristic ‘face of giant panda’ sign[omcr.oxfordjournals.org]

  • Mercury Poisoning

    The T2-weighted MRI images of the patient's brain initially showed multiple hyperintense lesions in cerebral white matter, left globus pallidus, and putamen, which also improved[ncbi.nlm.nih.gov]

  • Hallervorden-Spatz Syndrome

    This virtually pathognomonic radiographic abnormality, called the eye-of-the-tiger sign, comprises hyperintensities within a hypointense medial globus pallidus on T2-weighted[ncbi.nlm.nih.gov] Psychiatric symptoms with cognitive decline, reminiscent of frontotemporal dementia, were prominent in patients with atypical pantothenate kinase–associated neurodegeneration[nejm.org] […] pattern of hyperintensity within the hypointense medial globus pallidus.[ncbi.nlm.nih.gov]

  • Neurodegeneration with Brain Iron Accumulation

    Even before the globus pallidus hypointensity developed, patients with mutations could be distinguished by the presence of isolated globus pallidus hyperintensity on T2-weighted[ncbi.nlm.nih.gov] Ophthalmic examination was sometimes limited by cognitive ability.[ncbi.nlm.nih.gov] ) in specific brain regions (including globus pallidus interna and externa, substantia nigra, thalamus, putamen, and caudate) on T1- and T2-weighted studies, presence of the[ajnr.org]

  • Fucosidosis

    Figure 2: Magnetic resonance imaging brain T2-weighted axial image showing hypointensity of globus pallidus bilaterally and the subcortical hyperintensity (a), T1-weighted[pediatricneurosciences.com] […] described in 1968 by Durand and colleagues, in two brothers and enzyme was reported in the same year by Van Hoff and Hers. [2], [3] Common clinical features include progressive cognitive[annalsofian.org] To the best of our knowledge, the combination of hypointensity of the globus pallidus and hyperintensity in its laminae on T2-weighted MR images has not been reported in other[ajnr.org]

  • Central Pontine Myelinolysis

    […] of Globus Pallidus (broad arrow), suggestive of Extrapontine myelinolysis.[ipfs.io] However, in the absence of these infections 20–30% of patients will develop neurocognitive defects: human immunodeficiency virus (HIV)‐1‐associated cognitive motor complex[doi.org] weighted magnetic resonance scan image showing bilaterally symmetrical hyperintensities in caudate nucleus (small, thin arrow), putamen (long arrow), with sparing of globus[en.wikipedia.org]

  • Neurofibromatosis Type 1

    Rarely, hyperintensities and mild mass effect have been reported in the globus pallidus on T1-weighted images.[emedicine.com] (2%) Cognitive: Developmental delay Learning disabilities- hyperactivity and/or speech problems occur in 50% Mental retardation (8% of patients) Other-occasional: Syndactyly[en.wikibooks.org] If the T2 lesions show enhancement, glioma development should be suspected.[emedicine.com]

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