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3,086 Possible Causes for Cognitive Defect, Muscle Twitch, Onset of Disease between 25 and 40 Years of Age

  • Wilson Disease

    twitching, tremor and contractions.[dystonia-europe.org] Onset is slow and begins between 11 and 25 years of age. Signs and Symptoms In about 40 to 50% of patients, the disease first affects the central nervous system (CNS).[diagnose-me.com] If this part of the brain is damaged in some way, the wrong muscles contract when we try to move or the muscles contract unnecessarily even when we do not move, causing uncontrollable[dystonia-europe.org]

  • Hypoglycemia

    Symptoms of muscle twitching, irritability, and/or increased urination. Poor appetite that does not improve. If you notice excessive sleepiness, confusion.[chemocare.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Kidney Insufficiency

    […] mass muscle twitching and cramps easy bruising and bleeding blood in your stools hiccups excessive thirst decreased interest in sex impotence insomnia sleep apnea You may[healthline.com] twitching or cramps Breath odor Easy bruising, or blood in the stool Excessive thirst Frequent hiccups Problems with sexual function Menstrual periods stop (amenorrhea) Shortness[ufhealth.org] […] to your skin, called uremic frost drowsiness mental cloudiness numbness in your hands and feet restless leg syndrome brittle hair and nails itching weight loss a loss of muscle[healthline.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Chronic Fatigue Syndrome

    BFS has a variety of symptoms, including (but not limited to) frequent muscle twitches, muscle cramping, easy muscle fatigue, muscle aches and a "stiff" feeling, shakiness[web.archive.org] defects, joint/muscle pain, and headaches [ 1, Brenu EW, Staines DR, et al.[dx.doi.org] Three patients reported that they had first-degree relatives with muscle cramps or muscle twitching but nothing to suggest ALS.[nextination.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Acute Amphetamine Intoxication

    twitching Risky sexual behavior Amphetamines are meant to produce short-term, immediate effects on the user.[projectknow.com] Caffeine Mechanism adenosine antagonist decreased GABA activity (wakefulness) Intoxication presentation restlessness, insomnia diuresis muscle twitching cardiac arrhythmias[medbullets.com] […] rigidity Myoclonic jerks Twitching Choreiform movements 3.[clinicaladvisor.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Paraneoplastic Syndrome

    Accordingly, this syndrome is associated with muscle weakness, muscle wasting, and muscle twitching.[brighamandwomens.org] […] to muscle twitching and cardiac arrhythmias.[merckmanuals.com] Over the course of time, fine muscle twitching can progress to more pronounced abnormal movements and postures of the arms and legs (choreoathetosis).[rarediseases.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Primary Progressive Multiple Sclerosis

    We present three patients with a clinical course and cerebrospinal fluid findings consistent with a diagnosis of primary progressive multiple sclerosis (PPMS). Extensive and repeated magnetic resonance imaging (MRI) examinations showed only diffuse abnormality in brain and spinal cord, but no focal lesions. We propose[…][ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Multiple Sclerosis

    […] like difficulty walking or problems with coordination twitching, tingling, numbness and pain in certain areas of the body sexual problems in men and women...[medicinenet.com] This disorder is characterized by normal cognition, coarse faces and dysostosis multiplex, hepatosplenomegaly, and cardiac valve disease.[malacards.org] […] of the facial muscles): May also be a presenting symptom Eye symptoms: Including diplopia on lateral gaze (33% of patients) Heat intolerance Constitutional symptoms: Especially[emedicine.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Huntington's Disease

    For bystanders these muscle twitches are often invisible or can be explained as nervousness.[ncbi.nlm.nih.gov] In addition to motor symptoms and cognitive deterioration, neuropsychiatric symptoms comprise part of the Huntington’s disease phenotype. 1 – 3 The genetic defect underlying[doi.org] Physical symptoms Rapid, involuntary movements of the fingers, limbs, and facial muscles (chorea); this varies in severity from mild twitching to more severe thrashing as[labtestsonline.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Hypoparathyroidism

    twitching and spasms (tetany) that affect the mouth, throat, arms, and hands Seizures Brittle nails Patchy hair loss Fatigue or weakness Painful menstruation Dry skin Headaches[tgh.org] Children may present with unspecific features such as cognitive and or motor delay, slowness, ungueal, dental and skin anomalies.[endocrine-abstracts.org] Tetany might also include muscle discomfort and twitches or spasms of the muscles of your face, throat or arms.[mayoclinic.org]

    Missing: Onset of Disease between 25 and 40 Years of Age

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