Create issue ticket

1,871 Possible Causes for Cognitive Developmental Delay, Delayed Bone Age, Wide Space Between the First and Second Toe

  • Seckel Syndrome

    bone age, hip dysplasia, and elbow dislocation (Faivre et al. 2002).[preventiongenetics.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] age delay 2 6 9.[scielo.br]

  • Dubowitz Syndrome

    Analysis of approximately 30 cases reveals prevalence of growth failure and delayed bone age, mild microcephaly, broad forehead with sparse frontal hair, telecanthus, blepharophimosis[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The feeding difficulties, developmental and cognitive delay, mottled skin, drug-induced long QT syndrome, short stature, microcephaly, small ears, 2–3 cutaneous syndactyly[journals.plos.org]

  • Multiple Congenital Anomalies - Hypotonia - Seizures Type 3

    […] ossification centers, wide and long femoral necks, and delayed bone age.[bio2rdf.org] , delayed bone age, pectus excavatum and osteopenia), inverted nipples and dysmorphic features including high and narrow forehead, frontal bossing, short nose, depressed nasal[mendelian.co] All patients also had some type of skeletal findings, including scoliosis, pectus excavatum, short upper extremities, slender and osteopenic long bones with large secondary[bio2rdf.org]

    Missing: Wide Space Between the First and Second Toe
  • Russell-Silver Syndrome

    However, in each child with RSS, a particular attention should be given to a decreased height velocity, a severely delayed bone age as well as a history of major perinatal[ncbi.nlm.nih.gov] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Children with RSS have an increased risk for developmental delay (both motor and cognitive) and learning disabilities.[gemssforschools.org]

  • Waisman Syndrome

    Optz et. al. (1964) pointed out that the delayed ossification of bones represents an arrest of bone development.[docslide.com.br] delay, cognitive impairment, macroencephaly, and, in some, seizures; EO parkinsonism with tremor appeared subsequently as the presenting symptom.[ng.neurology.org] […] phenotype in individuals with Down syndrome that includes significant delay in nonverbal cognitive development accompanied by additional, specific deficits in speech, language[onlinelibrary.wiley.com]

    Missing: Wide Space Between the First and Second Toe
  • Skeletal Dysplasia

    A 14% of patients showed a low mean GH concentration during sleep, presenting also a markedly low IGF-1 level and marked delay of bone age [ 81 ].[intechopen.com] All of the patients demonstrated pre-school onset of a cognitive developmental delay with a shortened attention span.[ncbi.nlm.nih.gov] , hypotonia and bony abnormalities including marked cranial sclerosis and sclerosis of the ribs and long bones, which evolved in severity in the son between the ages of 2[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Early Infantile Epileptic Encephalopathy Type 2

    Radiologic features include delayed bone age, cone-shaped epiphyses, shortened long tubular bones, and ovoid vertebral bodies.[mendelian.co] Patients with a SYNGAP1 mutation have a developmental delay, cognitive regression and some patients have a autism.[molgen.ua.ac.be] developmental delay and intellectual disability.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Mucopolysaccharidosis

    It can cause a variety of different effects such as poor motor function, stiffness of joints, laxity of ligaments, cognitive impairment and developmental delays.[manchesterneurophysio.co.uk] In addition to developing somatic symptoms, patients having the neuronopathic form of the disease also display developmental delay and cognitive impairment in early childhood[touchneurology.com] Impaired cognitivity Developmental delay Severe behavioral problems X Hearing loss (conductivity/ neurosensitivity or both) Communicating hydrocephalus (normal absorption[slideshare.net]

    Missing: Wide Space Between the First and Second Toe
  • Aarskog Syndrome

    The main findings are asynchronic and delayed bone age, shortened long tubular bones with wide metaphyses, brachyphalangy, hypoplasia of the middle phalanges of the fifth[ncbi.nlm.nih.gov] […] and developmental delays.[healthline.com] Other Manifestations delayed puberty mild pectus excavatum prominent umbilicus INVESTIGATIONS: 1. Imaging Studies 1. Skeletal X-Rays delayed bone age MANAGEMENT: 1.[web.archive.org]

    Missing: Wide Space Between the First and Second Toe
  • Hypogonadotropic Hypogonadism

    Furthermore, disturbances of skeletal development may be noted as an overall delayed bone age and a reduced peak bone mass.[symptoma.com] While the spectrum of cognitive abilities extends much higher than originally described, developmental delays, cognitive impairments and behavioural disorders are common and[dx.doi.org] In addition the boy developed delay of puberty, bone age, and closure of the epiphyseal lines of long bones with tall stature.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe

Similar symptoms