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1,246 Possible Causes for Cognitive Developmental Delay, Dull Facial Expression, Wide Space Between the First and Second Toe

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] […] variants: or Down's syndrome Definition of Down syndrome : a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in[merriam-webster.com] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

  • Dementia

    Cognitive Decline in a Young Adult with Pre-Existent Developmental Delay – What the Adult Neurologist Needs to Know Phillipa J.[web.archive.org]

    Missing: Wide Space Between the First and Second Toe
  • Mental Retardation

    The focus of this report is the child with cognitive developmental delays rather than those with motor delays or language delays solely.[pediatrics.aappublications.org] To identify most (if not all) conditions with ID, we searched for entries with either “mental retardation” or “developmental delay”, “intellectual disability”, and “cognitive[dx.doi.org] CI, cognitive impairment; DD, developmental delay; ID, intellectual disability; MR, mental retardation.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov] Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and second toe [ more ][rarediseases.info.nih.gov]

    Missing: Dull Facial Expression
  • Juvenile Myxedema

    cognitive delay (cretinism).[reference.medscape.com] Mortality/Morbidity Untreated congenital hypothyroidism in early infancy results in profound growth failure and disrupted development of the CNS, leading to developmental[reference.medscape.com]

    Missing: Wide Space Between the First and Second Toe
  • Myotonic Dystrophy

    . • Other potential long-term complications include developmental delay, learning disabilities, behavioral problems, and cognitive impairment. • A multidisciplinary team approach[medlink.com] They may have cognitive impairment, delayed speech, difficulty eating and drinking and various other developmental delays. Most will learn to walk.[mda.org] They may have cognitive impairment, delayed speech, difficulty eating and drinking, and various other developmental delays. 15 The childhood-onset form of DM1, before the[mda.org]

    Missing: Wide Space Between the First and Second Toe
  • Iron Deficiency

    The latter include decreased aerobic work performance, hair loss, developmental delay, cognitive and intellectual impairment, adverse pregnancy outcome, and impaired immune[www2.gov.bc.ca] Reversal of developmental delays in iron-deficient anaemic infants treated with iron. Lancet 1993;341(8836):1-4. Lozoff B, Jimenez E, Wolf AW.[cdc.gov] Iron deficiency and cognitive function. Annu Rev Nutr 1993;13:521-37. Idjradinata P, Pollitt E.[cdc.gov]

    Missing: Dull Facial Expression Wide Space Between the First and Second Toe
  • Allergic Rhinitis

    Local allergic rhinitis is a newly described type of rhinitis involving nasal production of specific immunoglobulin (slg) E antibodies in the absence of atopy. It can affect patients previously diagnosed with non-allergic rhinitis. Evidence for this entity is supported by clinical symptoms, local production of slgE, a type 2[…][ncbi.nlm.nih.gov]

    Missing: Cognitive Developmental Delay Wide Space Between the First and Second Toe
  • Waisman Syndrome

    delay, cognitive impairment, macroencephaly, and, in some, seizures; EO parkinsonism with tremor appeared subsequently as the presenting symptom.[ng.neurology.org] […] phenotype in individuals with Down syndrome that includes significant delay in nonverbal cognitive development accompanied by additional, specific deficits in speech, language[onlinelibrary.wiley.com] The symptoms are similar: developmental delays gr oss and fine motor skill delays speech and language delays learning and behavior problems hyperextensible joints anxiety[fragilexfiles.com]

    Missing: Dull Facial Expression Wide Space Between the First and Second Toe
  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The feeding difficulties, developmental and cognitive delay, mottled skin, drug-induced long QT syndrome, short stature, microcephaly, small ears, 2–3 cutaneous syndactyly[journals.plos.org] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Dull Facial Expression