Create issue ticket

3,858 Possible Causes for Cognitive Developmental Delay, Sleep Apnea, Wide Space Between the First and Second Toe

  • Down Syndrome

    A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] […] variants: or Down's syndrome Definition of Down syndrome : a congenital condition characterized especially by developmental delays, usually mild to moderate impairment in[merriam-webster.com] Obstructive sleep apnea (OSA) is more common in children with Down syndrome, affecting up to 60% of patients, and may persist in up to 50% of patients after adenotonsillectomy[ncbi.nlm.nih.gov]

  • Obesity

    Cell 77 : 627 – 638 63 2004 A de novo mutation affecting human TrkB associated with severe obesity and developmental delay.[doi.org] Diagnosis of obstructive sleep apnea is made when symptomatic patients have an apnea– hypopnea index — the number of episodes of apnea and hypopnea per hour of total sleep[doi.org] Nat Neurosci 7 : 1187 – 1189 64 , , , , , , , , , , , , , , Impaired cognitive function, hyperactivity and severe obesity in a child with functional loss of one copy of BDNF[doi.org]

    Missing: Wide Space Between the First and Second Toe
  • Insomnia

    Some children with significant developmental delay or cognitive impairment may not respond to behavioral management and may benefit from judicious use of hypnotics. 4 Don’[choosingwisely.org] Convert to ICD-10-CM : 780.51 converts approximately to: 2015/16 ICD-10-CM G47.30 Sleep apnea, unspecified Approximate Synonyms Insomnia w sleep apnea Insomnia with sleep[icd9data.com] Sleep apnea presence and severity were not related to rates of insomnia-remission or treatment-resistance following treatment.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Waisman Syndrome

    delay, cognitive impairment, macroencephaly, and, in some, seizures; EO parkinsonism with tremor appeared subsequently as the presenting symptom.[ng.neurology.org] Obstructive sleep apnea in adults with Down syndrome. J Clin Sleep Med 2009; 15: 317–23. Urv TK, Zigman W, Silverman W.[sindromedownvidaadulta.org] […] phenotype in individuals with Down syndrome that includes significant delay in nonverbal cognitive development accompanied by additional, specific deficits in speech, language[onlinelibrary.wiley.com]

    Missing: Wide Space Between the First and Second Toe
  • Dubowitz Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] The feeding difficulties, developmental and cognitive delay, mottled skin, drug-induced long QT syndrome, short stature, microcephaly, small ears, 2–3 cutaneous syndactyly[journals.plos.org] Severe obstructive sleep apnea in a patient with spinal muscle atrophy. Chest . 2004 Nov. 126(5):1705-7. [Medline] . [Full Text] . Yasuma F, Kuru S, Konagaya M.[emedicine.medscape.com]

  • Costello Syndrome

    Hypotonia and developmental delay are typical in infancy, and mental retardation can be diagnosed in older patients.[ncbi.nlm.nih.gov] KEYWORDS: Costello syndrome; HRAS; obstructive sleep apnea; pulmonary; respiratory; upper airway[ncbi.nlm.nih.gov] delay)/MR (mental retardation) (100%) Micah test gross motor, fine motor, and cognitively at about a 6y/o.[waltersfamily.wordpress.com]

    Missing: Wide Space Between the First and Second Toe
  • Early Infantile Epileptic Encephalopathy Type 6

    Disease onset occurs in the first year of life, followed by developmental delay with cognitive and behavioral dysfunction and substantially elevated risk of premature death[ncbi.nlm.nih.gov] Obstructive sleep apnea is common in medically refractory epilepsy patients.[ncbi.nlm.nih.gov] delay or cognitive outcome did not differ between both groups.[pediatricneurologybriefs.com]

    Missing: Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Developmental delay may be temporal or permanent; for example, in achondroplasia, motor development may be delayed in the first 2 years, due to macrocephaly and ligamentous[musculoskeletalkey.com] […] or commonly referred to as Sleep Apnea. 18. frequent respiratory infections 19. frequent ear infections. 20. connective tissue disorder 21. dislocation of the shoulders 22[tawnymullins77.blogspot.com]

  • Prader-Willi Syndrome

    […] of above symptoms to food cravings, developmental and cognitive delay, behavior problems, especially surrounding food and food cravings, scoliosis, and short stature Criteria[arupconsult.com] apnea (OSA), especially early in treatment.[ncbi.nlm.nih.gov] , physical and other developmental delays; teachers should be aware of cognitive differences between genetic subtypes Exercise to improve poor muscle tone Children should[intellectualdisability.info]

    Missing: Wide Space Between the First and Second Toe
  • Velocardiofacial Syndrome

    Management for infants and preschoolers is usually centered on correcting feeding difficulties and developmental delays, however, in children of school age, treatment is centered[symptoma.com] Palatoplasties have variable success, and pharyngeal flaps (PPF) increase the obstructive sleep apnea risk.[ncbi.nlm.nih.gov] The association of developmental delays (particularly in language) are very common in patients with 22q11DS.[scielo.conicyt.cl]

    Missing: Wide Space Between the First and Second Toe

Similar symptoms