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296 Possible Causes for Cold Agglutinin Disease

  • Infectious Mononucleosis

    Spencer and Hans Kerzel Andersen, Cold Agglutinin Production and Cytomegalovirus Infection, Scandinavian Journal of Infectious Diseases, 6, 2, (109), (1974). G.[dx.doi.org] Roelcke, Cold agglutinins of anti-Pr specificity in rubella embryopathy, Annals of Hematology, 10.1007/BF01695471, 64, 6, (277-280), (1992). G.W.G.[dx.doi.org] Dieter Roelcke, Serology, Biochemistry, and Pathology of Antigens Defined by Cold Agglutinins, Molecular Basis of Human Blood Group Antigens, 10.1007/978-1-4757-9537-0_4,[dx.doi.org]

  • Non-Hodgkin Lymphoma

    Therapy may be required to correct hemolytic anemia in patients with chronic cold agglutinin disease; rituximab, cyclophosphamide, and steroids are often employed.[ 30 ] Occasionally[web.archive.org] Therapy may be required to correct hemolytic anemia in patients with chronic cold agglutinin disease; rituximab, cyclophosphamide, and steroids are often employed.[ 41 ] Occasionally[cancer.gov] , a heated room is required for patients whose cold agglutinins become activated by even minor chilling.[web.archive.org]

  • Hemolytic Anemia

    agglutinin disease keep warm Complications warm agglutinin lymphoproliferative disease venous thromboembolism cold agglutinin peripheral gangrene Please rate topic.[medbullets.com] Cold agglutinin diseaseCold agglutinin disease is associated with cold IgM autoantibodies.[cancertherapyadvisor.com] Rituximab for primary chronic cold agglutinin disease: a prospective study of 37 courses of therapy in 27 patients. Blood. 2004;103:2925-28.[rarediseases.org]

  • Mycoplasma Pneumonia

    It is a human pathogen that causes the disease mycoplasma pneumonia, a form of atypical bacterial pneumonia related to cold agglutinin disease. It can cause epidemics.[umoduzeq.ga] Complications Erythema multiforme, Raynaud’s disease, cold agglutinin haemolysis; less commonly, neurological, cardiovascular, musculoskeletal defects.[medical-dictionary.thefreedictionary.com] Simultaneous occurrence of cold agglutinin hemolytic anemia and central nervous system disease due to Mycoplasma pneumonia is extremely rare.[ncbi.nlm.nih.gov]

  • Multiple Myeloma

    Primary chronic cold agglutinin disease: a population based clinical study of 86 patients. Haematologica 2006; 91 (4) :460–6 [ PubMed ] [ Google Scholar ] 81.[ncbi.nlm.nih.gov] Blood diseases Cold agglutinin disease (CAD) is frequently associated with MGUS (mainly IgM-κ).[doi.org] The monoclonal immunoglobulin binds to erythrocyte carbohydrate antigens resulting in hemolytic anemia, Raynaud phenomenon, and acrocyanosis after cold exposure. 80 Warm antibody[doi.org]

  • Chronic Lymphocytic Leukemia

    agglutinin disease Cold agglutinin disease (CAD), where clonal IgM binds to erythrocytes in the cool peripheries, is associated with chronic lymphoproliferative disorders[haematologica.org] Two such diseases are paraneoplastic pemphigus, where immunoglobulins are cross-reactive with epitopes located at the dermal-epidermal junction, and cold agglutinin disease[haematologica.org] However, in a few cases, including paraneoplastic pemphigus and cold agglutinin disease, there is evidence that the CLL clone produces the pathological antibody.[haematologica.org]

  • Waldenstrom Macroglobulinemia

    agglutinin disease.[ncbi.nlm.nih.gov] […] neuropathy, amyloidosis, cryoglobulinemia, cold-agglutinin disease, or evidence of disease transformation should be considered for therapy.[ncbi.nlm.nih.gov] , cryoglobulinemia, cold-agglutinin disease, or transformed disease should be considered for therapy.[ncbi.nlm.nih.gov]

  • Mycoplasma Infection

    Abstract We describe a case of cold agglutinin disease, secondary to Mycoplasma pneumoniae infection, which presented with anaemia and abdominal pains in apparent succession[ncbi.nlm.nih.gov] Cold agglutinin disease/hemolytic anemic patients may also be treated with plasmapheresis, glucocorticoids and warming.[symptoma.com] Cold agglutinins are cross reactive antibodies against red blood cells.[symptoma.com]

  • Granulomatosis with Polyangiitis

    Granulomatosis with polyangiitis is characterized by necrotizing granulomatous inflammation, small- and medium-sized vessel vasculitis, and focal necrotizing glomerulonephritis, often with crescent formation. Typically, the upper and lower respiratory tract and the kidneys are affected, but any organ may be. Symptoms[…][merckmanuals.com]

  • Malignant Fibrous Histiocytoma

    Malignant fibrous histiocytoma, also known as pleomorphic undifferentiated sarcoma not otherwise specified, arises in numerous organs. The first-line treatment is complete excision of the mass, but in some cases postoperative chemo- and/or radiotherapy is recommended. Only a few cases of malignant fibrous[…][ncbi.nlm.nih.gov]

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