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57 Possible Causes for Cold Agglutinin Disease, Neck Mass

  • Infectious Mononucleosis

    agglutinin disease, an autoimmune disease in which abnormal circulating antibodies directed against red blood cells can lead to a form of autoimmune hemolytic anemia.[] Spencer and Hans Kerzel Andersen, Cold Agglutinin Production and Cytomegalovirus Infection, Scandinavian Journal of Infectious Diseases, 6, 2, (109), (1974). G.[] The cold agglutinin detected is of anti-i specificity. Diagnostic modalities for infectious mononucleosis include: Person's age, with highest risk at 10 to 30 years.[]

  • Non-Hodgkin Lymphoma

    Therapy may be required to correct hemolytic anemia in patients with chronic cold agglutinin disease; rituximab, cyclophosphamide, and steroids are often employed.[ 30 ] Occasionally[] High-resolution computed tomography (CT) of the temporal bone and CT of the neck detected a mass lateral to the left tympanic membrane and another mass in the anterior neck[] Symptoms The most common symptom of non-Hodgkin's lymphoma is a mass or swelling of the lymph nodes of the neck, collarbone, groin, and armpit.[]

  • Mycoplasma Pneumonia

    It is a human pathogen that causes the disease mycoplasma pneumonia, a form of atypical bacterial pneumonia related to cold agglutinin disease. It can cause epidemics.[] Less common symptoms include earaches, eye pain, muscle aches, joint stiffness, skin rash, swollen lymph nodes* in the neck, and difficulty breathing.[] Complications Erythema multiforme, Raynaud’s disease, cold agglutinin haemolysis; less commonly, neurological, cardiovascular, musculoskeletal defects.[]

  • Multiple Myeloma

    Primary chronic cold agglutinin disease: a population based clinical study of 86 patients. Haematologica 2006; 91 (4) :460–6 [ PubMed ] [ Google Scholar ] 81.[] Noncontrast MR imaging of the neck was performed on a 1.5T magnet. Contrast was not administered because of a reported allergy to gadolinium.[] Blood diseases Cold agglutinin disease (CAD) is frequently associated with MGUS (mainly IgM-κ).[]

  • Chronic Lymphocytic Leukemia

    agglutinin disease Cold agglutinin disease (CAD), where clonal IgM binds to erythrocytes in the cool peripheries, is associated with chronic lymphoproliferative disorders[] Herein, we present a case of a 76-year-old Caucasian man with a very large fungating, ulcerating mass, involving the right neck and parotid area, which developed while he[] Two such diseases are paraneoplastic pemphigus, where immunoglobulins are cross-reactive with epitopes located at the dermal-epidermal junction, and cold agglutinin disease[]

  • Waldenstrom Macroglobulinemia

    agglutinin disease.[] D J Bowyer, I Smillie and I Ganly, Diagnostic utility of freehand core-needle biopsy in head and neck masses, The Journal of Laryngology & Otology, 10.1017/S0022215112002915[] […] neuropathy, amyloidosis, cryoglobulinemia, cold-agglutinin disease, or evidence of disease transformation should be considered for therapy.[]

  • Malignant Fibrous Histiocytoma

    Diagnosis Patients often present with a painless soft tissue mass in the neck that, before biopsy, may be confused with lymphomas, other soft tissue sarcomas, and metastatic[] Ten patients presented with a palpable mass or swelling of the face and neck, and 3 patients, with nasal obstruction, which had first been noticed 1 month to 3 years before[] Head and neck MFH can be confused with a variety of fibrous tumors and inflammatory conditions, including neurilemmoma, fibromatosis, premature sarcoma, hemangiopericytoma[]

  • Mycoplasma Infection

    Abstract We describe a case of cold agglutinin disease, secondary to Mycoplasma pneumoniae infection, which presented with anaemia and abdominal pains in apparent succession[] Less common symptoms include earaches, eye pain, muscle aches, joint stiffness, skin rash, swollen lymph nodes* in the neck, and difficulty breathing.[] Cold agglutinin disease/hemolytic anemic patients may also be treated with plasmapheresis, glucocorticoids and warming.[]

  • Paroxysmal Cold Hemoglobinuria

    Cold agglutinin disease Cold sensitive antibody Hemolytic anemia List of hematologic conditions[] Groin pain active patient37 Gynecomastia Halitosis Headache13 Headache acute11 Headache and facial pain36 Headache chronic11 Head and neck soft tissue masses Heartburn and[] Chronic cold agglutinin disease (CAD) is a subgroup of autoimmune hemolytic anemia.[]

  • Proliferating Angioendotheliomatosis

    It is known that cold agglutinin disease rarely leads to digital gangrene.[] […] axilla, groin, and oral cavity Deep-seated, multilocular masses Cytogenic analysis of children with cystic hygromas to detect aneuploidy XO Tx: tranvaginal US, may reoccur[] agglutinin disease.[]

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