Create issue ticket

216 Possible Causes for Cold-Induced Muscle Cramps, Disruption Plasma Membrane

  • Ehlers-Danlos Syndrome Classic-Like Type 1

    Cases have been reported of patient manifesting chronic widespread pain, chronic headache occurring during pregnancy, depression and/or cold-induced muscle cramps, who have[bredagenetics.com] cramps or myalgia.[bredagenetics.com] […] skeletal muscle disorder characterized by muscle stiffness and an inability of the muscle to relax after voluntary contraction, but can infrequently manifest as generalized muscle[bredagenetics.com]

  • Actinic Keratosis

    Firstly, there is rapid cellular necrosis through the disruption of the plasma membrane and mitochondrial swelling.[doi.org] Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. Cancer Res 2004 ;64: 2833 - 2839 8.[doi.org] Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. Cancer Res. 2004;64:2833–9. PubMed Google Scholar 113.[doi.org]

    Missing: Cold-Induced Muscle Cramps
  • Oral Candidiasis

    Fluconazole is a potent and selective inhibitor of fungal enzymes involved in the synthesis of ergosterol, an important constituent of the plasma cell membrane.[pmj.bmj.com] It therefore disrupts cell wall formation leading to leakage of cellular contents and cell death.[pmj.bmj.com] It is well absorbed by the gastrointestinal tract and the plasma levels are over 90% of the levels achieved with intravenous administration and the levels in saliva and sputum[pmj.bmj.com]

    Missing: Cold-Induced Muscle Cramps
  • Toxoplasmosis

    (open white arrowhead: T. gondii inner membrane complex [IMC]; filled white arrowhead: T. gondii plasma membrane; black arrowhead: PVM). Bars: 250 nm.[doi.org] Frequently the plasma membrane of the parasite itself appeared damaged and IIGP1 label was associated with internal parasite membranes ( Figure 6 C) suggesting destruction[doi.org] It remains to be established whether the p47 GTPases also contribute to perforation of the T. gondii plasma membrane or whether the p47 GTPase-dependent removal of the protective[doi.org]

    Missing: Cold-Induced Muscle Cramps
  • Staphylococcus Aureus

    This mechanism plays a major role in disrupting the humoral host defense [ 45, 48 ].[doi.org] SAPs are also able to break down portions of immunoglobulins, which are glycoproteins synthesized and secreted by plasma cells that function as antibodies.[doi.org] The extracellular PLs are capable to target and digest the membrane phospholipids, the major component of all host cell membranes, thereby facilitating microorganism invasion[doi.org]

    Missing: Cold-Induced Muscle Cramps
  • Diabetes Mellitus

    […] of cell membrane ion transport, and a rapid shift in extracellular and intracellular fluids resulting in changes in osmolality.[web.archive.org] Prevention might include avoidance of excessive hydration and rapid reduction of plasma osmolarity, a gradual decrease in serum glucose, and maintenance of serum glucose between[web.archive.org] […] mechanisms have been proposed, which include the role of cerebral ischemia/hypoxia, the generation of various inflammatory mediators ( 72 ), increased cerebral blood flow, disruption[web.archive.org]

    Missing: Cold-Induced Muscle Cramps
  • Cardiac Arrhythmia

    Recent findings indicated that chronic treatment with various drugs not only inhibits hERG channels but also decreases hERG channel expression in the plasma membrane of cardiomyocytes[ncbi.nlm.nih.gov] The mechanisms involve the disruption of hERG trafficking to the surface membrane or the acceleration of hERG protein degradation.[ncbi.nlm.nih.gov]

    Missing: Cold-Induced Muscle Cramps
  • Stroke

    Disruption of cellular metabolism also impairs normal sodium-potassium plasma membrane pumps, producing an intracellular increase in sodium, which in turns increases intracellular[emedicine.com] […] viable for several hours because of marginal tissue perfusion. [10] Ischemic cascade On the cellular level, the ischemic neuron becomes depolarized as ATP is depleted and membrane[emedicine.com]

    Missing: Cold-Induced Muscle Cramps
  • Cerebral Thrombosis

    disruption in the blood-brain barrier and leakage of plasma into the interstitial space is a reversible phenomenon if the venous occlusion is successfully treated. [4] The[annalsofian.org] Cytotoxic edema caused by local ischemia, subsequently damages the energy-dependent cellular membrane pumps and induce intracellular swelling. [4] Vasogenic edema caused by[annalsofian.org]

    Missing: Cold-Induced Muscle Cramps
  • Myocardial Infarction

    Necrosis is characterised by the rapid loss of cellular homeostasis, rapid swelling as a result of the accumulation of water and electrolytes, early plasma membrane rupture[dx.doi.org] , and the disruption of cellular organelles.[dx.doi.org]

    Missing: Cold-Induced Muscle Cramps

Further symptoms