Create issue ticket

133 Possible Causes for Cold Intolerance, Painful Neuropathy

  • Fabry Disease

    Painful neuropathies may be treated with a variety of medications.[] The most prevalent signs and symptoms were: heart disease (60.6%), decreased or lack of sweating (42.3%), heat and cold intolerance (28.2%), and pain crises spreading throughout[] The clinical course of Fabry disease is usually marked by chronic pain, angiokeratomas, hypohidrosis, heat and cold intolerance, corneal opacities, renal failure, stroke and[]

  • Cryoglobulinemia

    painful in cold temperatures.[] intolerance, HTN, CHF Lab C4 and other complement proteins Cryoglobulinemia Type I Monoclonal cryoglobulinemia Underlying disease is often malignant; IgG (malignant myeloma[] Skin manifestations are usually the first signs and are usually moderate; in addition, cold intolerance, Raynaud phenomenon, purpura, or livedo reticularis often occurs.[]

  • Myxedema

    Signs and symptoms of peripheral neuropathy may include pain, numbness and tingling in the area affected by the nerve damage.[] Characteristic symptoms are weakness, cold intolerance, mental and physical slowness, dry skin, typical facies, and hoarse voice.[] Patients initially have cold intolerance that progresses to severe loss of heat from the body.[]

  • Alcoholic Neuropathy

    Abstract Five patients suffering from painful alcoholic neuropathy showed severe painful sensory disturbance in their extremities.[] Many people feel excess pain with exposure to cold due to increased sensitivity in alcoholic neuropathy.[] Your history of heavy alcohol use for years certainly is a frequent cause of such painful neuropathies.[]

  • Hashimoto's Thyroiditis

    Symptoms Common symptoms of the disease are dry skin, weight gain, cold intolerance, voice hoarseness, pressure symptoms in the neck from thyroid enlargement, tiredness, weight[] Depression, dementia, and other psychiatric disturbances Memory loss Joint pains and muscle cramps Hair loss from an autoimmune process directed against the hair follicles[] intolerance, weight gain, and constipation.[]

  • Anemia

    Peripheral Neuropathy Hypothyroidism is known to cause a condition known as peripheral neuropathy, which causes abnormal localized sensations and pain such as: Numbness Burning[] Fatigue or weakness Easy fatigue, loss of energy, and reduced physical capacity Cold intolerence Sensitivity to the cold may mean there is not enough oxygen being delivered[] This may lead to a variety of symptoms, including weight gain, fatigue, depression, dry skin, brain fog, cold intolerance, muscle cramps, and constipation.[]

  • Anorexia Nervosa

    Mild neuropathies, fatigue, and generalized weakness occur commonly. Pain threshold may be raised in anorexics.[] Makes frequent comments about feeling “fat” or overweight despite weight loss Complains of constipation, abdominal pain, cold intolerance, lethargy, and/or excess energy Denies[] […] body image–anorectics believe they are overweight even when significantly underweight Clinical Average 25% below normal weight:height ratio, absence of 3 menstrual periods, cold[]

  • Water Soluble Vitamin Deficiency

    (nerve destruction) and skin lesions Folate Megaoblastic (macrocytic) anemia, abdominal pain, diarrhea, birth defects Infants: 65 – 80 μg Children: 150 – 200μg Adolescents[] […] to cold, weight gain, and enlargement of the thyroid High doses may aggravate acne (rare from diet or typical supplement consumption) High doses may lead to a temporary block[] Iodine deficiency inhibits the synthesis of thyroid hormones resulting in hypothyroidism and it’s typical problems including fatigue, weight gain and intolerance to cold.[]

  • Systemic Scleroderma

    Neurological: Some patients experience numbness, tingling, and pain from various neuropathies (disorders of the nervous system), including carpal tunnel syndrome and other[] Raynaud’s attacks can be uncomfortable and associated with cold intolerance.[] For example, overuse injuries, osteoarthritis, and degenerative disc disease may result in joint pain.[]

  • Erythropoietic Protoporphyria

    Symptomatically, acute porphyrias primarily present with nervous system involvement, often with severe abdominal pain , vomiting , peripheral neuropathy and mental disturbances[] Additionally, the use of hematin and/or plasmapheresis in the setting of severe neuropathy and pain is advocated by certain authors.[] The symptoms include abdominal pain and cramps, nausea and vomiting, diarrhea or constipation, urinary retention, and the development of peripheral neuropathies with muscle[]

Further symptoms