Comedo: Causes & Reasons

Possible Causes for Comedo

A single lesion is a comedo. [dermnetnz.org]

Abstract Acne vulgaris makes its debut with the comedo. This is the undisputed hallmark of the disease. Several features distinguish acne comedonica. [link.springer.com]

A comedo is formed by the debris blocking the sebaceous duct and hair follicle. It is now known that comedones also involve inflammation (see causes of acne). [dermnetnz.org]

Acne Vulgaris

References[edit] ^ a b "Comedo". [en.wikipedia.org]

[…] by Propionibacterium acnes, and (5) inflammation both within and adjacent to the comedo. [oadoi.org]

Comedo Other names Plural: comedones[1] Illustration comparing a normal skin pore with a whitehead and a blackhead Specialty Dermatology A comedo is a clogged hair follicle [en.wikipedia.org]

Ductal Carcinoma in Situ

[…] and smears from 10 invasive comedo carcinomas. [ncbi.nlm.nih.gov]

Immunohistochemical and oncogene studies as they relate to comedo-type DCIS are discussed. [ncbi.nlm.nih.gov]

Periductal angiogenesis was not significantly related to the type of IDC but was more pronounced with comedo carcinomas. [ncbi.nlm.nih.gov]

Folliculotropic Mycosis Fungoides

Follicular involvement in cutaneous T-cell lymphoma commonly presents clinically with alopecia, follicular cysts, or comedo-like lesions usually associated with follicular [medscape.com]

Infiltrated plaques (55%), acneiform lesions (comedo-like and epidermal cysts) (45%), and follicular keratosis-pilaris-like lesions (45%) were the more prominent features. [ncbi.nlm.nih.gov]

[…] is limited to a perifollicular location with folliculotropism Occurs in two forms: with and without follicular mucinosis Presents with erythematous papules, plaques and comedo-like [dermpedia.org]

Cystic Acne Vulgaris

[…] comedones, inflammatory lesions and scars Comedones (open or closed) are cyst-like cavities filled with compact mass of keratinous material and numerous bacteria Closed comedo [pathologyoutlines.com]

On DermNet NZ: Acne, zits and pimples Causes of acne Acne treatment Comedo Facial acne images On other websites: Acne Vulgaris – Medscape Drugs & Diseases Books about skin [dermnetnz.org]

The word “ comedo ” was coined in the late 1800s. [onhealth.com]

Occupational Acne

Non-inflammatory acne is characterized by both open and closed comedo formation. [quizlet.com]

[…] acne vulgaris Synovitis acne pustulosis hyperostosis osteomyelitis syndrome Tropical acne 706.1 Excludes Applies To Acne: NOS conglobata cystic pustular vulgaris Blackhead Comedo [icd9data.com]

 Cases that persist beyond 4 weeks or have an onset after  In contrast to neonatal acne, comedo formation is prominent and pitted scarring can develop.  Infantile acne [slideshare.net]

Acne Tropicalis

The Evolution of the Comedo.- 6. The Dynamics of Primary Comedo Formation.- 7. The Dynamics of Secondary Comedo Formation.- 8. The Dynamics of Inflammation.- 9. [amazon.com]

The Evolution of the Comedo. [biblioteca.epn.edu.ec]

The Evolution of the Comedo.-Dynamics of Primary Comedo Formation.- Dynamics of Secondary Comedo Formation.- Dynamics of Inflammation, Inflammatory Lesions and Sequels. [geneeskundeboek.nl]

Acne Varioliformis

[…] by Propionibacterium acnes, and (5) inflammation both within and adjacent to the comedo. [dx.doi.org]

[…] one another via impairment of apoptosis and subsequent obstruction of the pilosebaceous duct, (3) androgen-mediated increases in sebum production, (4) colonization of the comedo [dx.doi.org]

Zinc-Responsive Necrolytic Acral Erythema

Externa (Ear Disease) (see also Therapies) 87 2 Pyoderma in Dogs (Bacterial Skin Infection) 91 2 Ear Margin Dermatosis 101 2 Nasal Depigmentation (Dudley Nose) 103 2 Schnauzer Comedo [isbn.nu]

[…] ultra-small silicon transistors that will.BEAPSEC - Summary Human skin Dry skin Sebaceous gland Acne vulgaris Propionibacterium acnes Cutaneous conditions Pimple Blackhead Comedo [swompius.tk]

Epidermal Nevus

Comedo naevus syndrome The comedo naevus is composed of a group of open comedones plugged with keratin and may arise on the head, trunk or limbs. [dermnetnz.org]

Sebaceous naevus Sweat gland naevus Comedo naevus Becker naevus. Melanocytic naevi are characterised by benign proliferation of melanocytic naevus cells. [dermnetnz.org]

Keratinocyte naevi • Verrucous epidermal naevus (VEN) – Epidermolytic VEN – Non-epidermolytic VEN Sebaceous naevi • Naevus sebaceus Follicular naevi • True hair-follicle naevus • Comedo [slideshare.net]

Malignant Neoplasm of the Breast

Infiltrating ductal carcinoma is the most commonly diagnosed breast tumor, found in about 75% of cases and infiltrating lobular, infiltrating medullary, colloid, comedo or [symptoma.com]

Ductal carcinoma in situ DCIS Microinvasive carcinoma of the breast Comedo Carcinoma of the breast: Comedo DCIS. And, I have a newer page about DCIS here. [breast-cancer.ca]

Cribriform DCIS (center) surrounded by comedo-type DCIS. Micropapillary carcinoma. [med-ed.virginia.edu]

Cribriform Comedo-Type Adenocarcinoma

Cribriform Comedo-type Adenocarcinoma What is Cribriform Comedo-type Adenocarcinoma of Colon and Rectum? [dovemed.com]

Affiliations PMID: 31314198 Free article Case Reports Colorectal cribriform comedo-type adenocarcinoma: a distinct subtype with poor prognosis? C Díaz Del Arco et al. [pubmed.ncbi.nlm.nih.gov]

Appelman and Maria Westerhoff}, journal={Journal of Clinical Pathology}, year={2021}, volume={75}, pages={483 - 487} } Background Cribriform comedo-type adenocarcinoma was [semanticscholar.org]

Breast Mucinous Carcinoma

Carcinoma intraduttale, tipo comedo. [senologiadiagnostica.it]

Intraductal carcinoma, comedo type. Distended duct with intact basement membrane and central tumor necrosis. View Media Gallery Breast cancer. [senologiadiagnostica.it]

DCIS is divided into comedo (ie, cribriform, micropapillary, solid) and noncomedo subtypes.This division provides additional prognostic information on the likelihood of progression [senologiadiagnostica.it]

Basaloid Penile Carcinoma

Definition / general Squamous cell carcinoma composed of uniform, small to intermediate cells in solid sheets or nests and often with central comedo-like necrosis ICD-0: 8083 [pathologyoutlines.com]

[…] tumor Images hosted on other servers: 6 cm fibrous white soft tissue tumor Microscopic (histologic) description Closely attached nests of tumor cells, often with central comedo-like [pathologyoutlines.com]

Comedo Carcinoma

Comedo-type ductal carcinoma in situ. [radiopaedia.org]

There is undoubtedly confusion in the minds of some as to the significance of the term comedo. [jamanetwork.com]

[…] and progression of comedo-DCIS. [ncbi.nlm.nih.gov]

Breast Mucinous Cystadenocarcinoma

Carcinoma intraduttale, tipo comedo. [senologiadiagnostica.it]

Intraductal carcinoma, comedo type. Distended duct with intact basement membrane and central tumor necrosis. View Media Gallery Breast cancer. [senologiadiagnostica.it]

Lobular Neoplasia

Lobular intraepithelial neoplasia [lobular carcinoma in situ] with comedo-type necrosis: A clinicopathologic study of 18 cases Oluwole Fadare et al. [pubmed.ncbi.nlm.nih.gov]

Original Articles Lobular Intraepithelial Neoplasia [Lobular Carcinoma In Situ] With Comedo-type Necrosis A Clinicopathologic Study of 18 Cases Fadare, Oluwole MD* † ‡; Dadmanesh [journals.lww.com]

[…] necrosis versus DCIS with comedo necrosis: Some examples of LCIS composed of classical type A or type B cells may show comedo necrosis in the involved spaces and may simulate [pathologyoutlines.com]

Nevus comedonicus Syndrome

Dilated Pore of Winer Clinical Manifestations Nevus Comedonicus The nevus was described in 1895 under the term “comedo nevus.” [news-medical.net]

Nevus comedonicus may require removal for cosmetic reasons or if severe inflammation sets in. surgical excision, shave excision, comedo extraction, or dermabrasion are some [news-medical.net]

Dowling Degos Disease Type 4

Histopathological examination from the comedo-like papule revealed hyperkeratotic epidermis follicular plugging along with antler-like elongation of rete ridges confined to [cureus.com]

[…] denigrates Dowling-Degos disease (DDD) as a possible alternative diagnosis.Clinically, the Japanese cases and, in particular, case 2 had axillary, black, verrucous lesions, "open comedo-like [jamanetwork.com]

It usually presents after puberty with reticular pigmentation of the flexures, particularly the axillae, groin, and submammary folds, blackhead comedo-like papules, and perioral [odermatol.com]

Dowling-Degos Disease Type 3

Histopathological examination from the comedo-like papule revealed hyperkeratotic epidermis follicular plugging along with antler-like elongation of rete ridges confined to [cureus.com]

It usually presents after puberty with reticular pigmentation of the flexures, particularly the axillae, groin, and submammary folds, blackhead comedo-like papules, and perioral [odermatol.com]

Few darkly pigmented comedo-like papules and few atrophic scars were noticeable over upper back and neck [Figure 1c]. [journals.lww.com]

Dowling-Degos Disease

All these patients showed reticular pigmentation of the folds; in six cases there were also pitted acneiforms scars and in five cases comedo-like lesions. [moh-it.pure.elsevier.com]

Dowling-Degos disease (DDD) is a rare genetic disease of the skin (reticulate pigmented anomaly), clinically characterized by flexural brown pigmented reticulate macules, comedo-like [pubmed.ncbi.nlm.nih.gov]

Specifically, there was no evidence of hidradenitis suppurativa, seborrheic keratoses, comedo-like lesions, hyperkeratotic follicular lesions, epidermoid cysts, pitted acne-like [escholarship.org]

Vulvar Eccrine Porocarcinoma

In addition to the intracytoplasmic luminal and cribriform pattern, necrosis was seen in the center of the nodules, giving the appearance of comedo-necrosis (Fig. 2b). [ncbi.nlm.nih.gov]

[…] broadly connected to the epidermis (arrow) (hematoxylin and eosin [H&E] staining; magnification × 40). b Tumor cells forming small glandular structures (arrowheads); areas of comedo-necrosis [ncbi.nlm.nih.gov]

Mucoepidermoid Thyroid Carcinoma

[…] pseudoinclusions) Mucocyte with clear to foamy or vacuolated cytoplasm, can have hyaline bodies (PAS+) in the cytoplasm Ciliated cells may be seen Can show extracellular mucin, comedo [pathologyoutlines.com]

Comedo necrosis and psammoma bodies may be seen Foci of associated papillary thyroid carcinoma are often seen Lymph nodes metastases, extrathyroidal invasion are common Mucoepidermoid [pathologyoutlines.com]

Granulosis Rubra Nasi

Sometimes small red papules and comedo-like lesions may be present. Read More [pubfacts.com]

[…] macules, papules, vesicles or even pustules may be seen over the sweat duct orifices.[4] Later numerous small telangiectasias may occur over the nose, cheeks, and chin.[15] Comedo-like [journals.lww.com]

[…] macules, papules, vesicles or even pustules may be seen over the sweat duct orifices.[4] Later numerous small telangiectasias may occur over the nose, cheeks, and chin.[1,5] Comedo-like [ncbi.nlm.nih.gov]

Reticulate Acropigmentation of Kitamura

Publication Analysis Top Keywords reticulate acropigmentation 12 acropigmentation kitamura 8 dermatoglyphics comedo-like 4 [pubfacts.com]

Fig 4: Comedo- like lesions and pitted acne-form scars near the angles of the mouth. [edoj.org.eg]

Few darkly pigmented comedo-like papules and few atrophic scars were noticeable over upper back and neck [Figure 1] c. [idoj.in]

Eccrine Papillary Adenocarcinoma

Shave biopsy specimen stained with H&E. a ×10 magnification showing cystic comedo necrosis (yellow arrow) surrounded by the dysplastic epithelium (blue arrow). b ×40 magnification [karger.com]

[…] hyperkeratosis, papillomatosis, and acanthosis with the top of a dermal cystic lesion lined by the dysplastic epithelium forming papillary fronds without stroma plus focally cystic comedo [karger.com]

Trichostasis Spinulosa

However, for cosmetic reasons, hairs within the individual plugs may be removed by pulling them out using tweezers, squeezing them out with a comedo extractor, or using depilatory [dermnetnz.org]

Black dots, also called comedo-like cadaver hairs, can be found in almost 50% of alopecia areata patients and indicate disease activity. [biblat.unam.mx]

Suggested causes of TS include acquired hyperkeratosis of the follicular infundibulum by internal factors with comedo formation, augmented clinical activity of hair papillae [ijtrichology.com]

Basaloid Squamous Cell Carcinoma

Strands of tumor cells often connected to overlying squamous epithelium Nuclei are round to oval with hyperchromatic nuclei with peripheral palisading, often with central comedo [pathologyoutlines.com]

Neither peripheral palisading nor comedo necrosis was present. A diagnosis of BSCC was given. [ncbi.nlm.nih.gov]

HIGH POWER VIEW Malignant epithelial island Comedo necrosis 12. [slideshare.net]

Familial Transverse Nasal Hyperpigmentation

Along the latter erythema, hyperpigmentation (3), milia, cysts and comedos (4), sometimes inherited by an autosomal dominant trait (1) may occur. Clinical course. [ejpd.com]

Micropapillary Carcinoma

Comedo-type DCIS in a 41-year-old woman. [pubs.rsna.org]

Comedo-type DCIS with microinvasion in a 53-year-old woman. [pubs.rsna.org]