Complement Fixing Antibody: Causes & Reasons

Possible Causes for Complement Fixing Antibody

Method: Immunoenzymatic method for the semiquantitative determination of complement-fixing antibodies in human serum, using a disposable device applied on the Chorus and Chorus [diesse.it]

Abstract The sera of 30 patients with complement-fixing antibodies to Mycoplasma pneumoniae (titres larger than or equal to 32) were treated with staphylococcal protein A. [ncbi.nlm.nih.gov]

ANTIBODIES IN HUMAN SERUM USING A DISPOSABLE DEVICE APPLIED ON THE CHORUS INSTRUMENTS Code 85340 Quantity 12 tests METHOD Complement fixation test TYPE Semiquantitative test [diesse.it]

Lymphocytic Choriomeningitis

Virus was isolated from their patient's blood and urine, and complement fixing antibodies were demonstrated in the patient's serum during convalescence. [jamanetwork.com]

antibodies to it. [nejm.org]

The serums of 2 persons who had worked for two years with the same virus strain and infected animals failed to fix complement. [jamanetwork.com]

Psittacosis

In the subsequent investigation of this problem, human psittacosis was defined as a fourfold rise in complement-fixing antibody titer to > or = 32 or a single titer of > or [ncbi.nlm.nih.gov]

[…] any combination of fever, chills, lower or upper respiratory disease, myalgia, headache, photophobia, and splenomegaly, plus a fourfold or greater change in psittacosis complement-fixing [cdc.gov]

(CF) antibody titer to at least 32 between two serum specimens obtained 2 or more weeks apart and studied at the same laboratory. [cdc.gov]

Hyperacute Graft Rejection

Lucisano Valim YM and Lachmann PJ (1991) The effect of antibody isotype and antigenic epitope density on the complement‐fixing activity of immune complexes: a systematic study [els.net]

Preformed DSA can cause hyperacute or accelerated acute rejection within minutes from the revascularization by binding to EC and fixing the complement; antibody-mediated complement [frontiersin.org]

[…] using chimaeric anti‐NIP antibodies with human Fc regions. [els.net]

Lymphogranuloma Venereum

The diagnosis of lymphogranuloma venereum was made by a fourfold rise in complement fixing antibody titer. Treatment with tetracycline was successful. [ncbi.nlm.nih.gov]

Dengue Fever

Human antibody to dengue soluble complement-fixing (SCF) antigens. J. Immunol. 111 : 1804-1809. [ PubMed ] [ Google Scholar ] 22. Garcia, G., D. W. Vaughn, and R. M. [ncbi.nlm.nih.gov]

Human antibody to dengue soluble complement-fixing (SCF) antigens. J. Immunol. 111 : 1804 -1809. ↵ Garcia, G., D. W. Vaughn, and R. M. Del Angel. 1997. [doi.org]

Both IgG subclasses can fix and activate the complement system effectively, whereas IgG2 and IgG4 are less effective in this respect ( 90 ). [cmr.asm.org]

Respiratory Syncytial Virus Infection

BACKGROUND: To evaluate the role of serum cytokines in the pathogenesis of respiratory syncytial virus (RSV) infection in infants with low birth weight (LBW). METHODS: A prospective observational study was performed, and hospitalized children with lower respiratory tract infection (LRTI) were recruited. Three[…] [ncbi.nlm.nih.gov]

Mycoplasma Infection

J Urol. 1980 Oct;124(4):469-71. Abstract Ureplasma urealyticum (T-mycoplasma) has been related to male infertility by some observers. To assess further this question 150 couples who presented for fertility had semen and cervical mucus cultures for mycoplasma. Positive cultures were obtained from 69 couples. There[…] [ncbi.nlm.nih.gov]

Dengue Hemorrhagic Fever

In Indonesia as well as in many developing countries both typhoid fever and dengue hemorrhagic fever (DHF) are still endemic and prevalent. In Indonesia the incidence of DHF in 1994 was 9.72/100,000 population with CFR of 2.5% and each year about 640,000-1,500,000 cases of typhoid fever were reported with mortality[…] [ncbi.nlm.nih.gov]

Rocky Mountain Spotted Fever

Alerts and Notices Synopsis   Rocky Mountain spotted fever (RMSF) is caused by the gram-negative bacterium Rickettsia rickettsii. It is the most severe rickettsial illness of humans; without treatment, the case fatality rate is 20%-30%. The disease is transmitted most commonly via the tick bite of the[…] [visualdx.com]

Colorado Tick Fever

Colorado tick fever virus is transmitted by Dermacentor andersoni ticks. In Canada, these ticks are found in the southern regions of British Columbia (Rocky Mountains) and Alberta, as well as southwestern Saskatchewan. Colorado tick fever should be clinically suspected in patients presenting with a biphasic febrile[…] [ncbi.nlm.nih.gov]

Paracoccidioidomycosis

Paracoccidioidomycosis (PCM) (also known as "Brazilian blastomycosis", "South American blastomycosis", "Lutz-Splendore-de Almeida disease" and "paracoccidioidal granuloma") is a fungal infection caused by the fungus Paracoccidioides brasiliensis. Though sometimes called South American blastomycosis,[…] [en.wikipedia.org]

Bubonic Plague

Bubonic plague: An infectious disease that is caused by the bacterium Yersinia pestis and is transmitted to humans from infected rats by the oriental rat flea. It is named for the characteristic feature of buboes (painfully enlarged lymph nodes) in the groin, armpits, neck, and elsewhere. Other symptoms of bubonic[…] [medicinenet.com]

Chronic Pulmonary Coccidioidomycosis

The presence of complement-fixing antibodies in CSF is diagnostic of coccidioidal meningitis and is important because CSF cultures are rarely positive. [merckmanuals.com]

Complement-fixing antibody (CFA) titers in this group tend to be somewhat high. [oncohemakey.com]

Serum IgG antibodies are detectable by complement fixation (CF) at a later time. 12 Quantitative complement-fixing antibody titers using IgG can be used to monitor disease [appliedradiology.com]

Herpes Gestationis

[…] type XVII hemidesmosomal protein antibodies hemidesmosome antibodies Herpes Gestationis Factor (Complement-Fixing Basement Membrane Zone Antibody IgG) HGF IgG BP 180 NC16A [ltd.aruplab.com]

Screening Panel Components Complement-fixing basement membrane zone antibodies by indirect immunofluorescence IgA basement membrane zone antibodies by indirect immunofluorescence [medicine.utah.edu]

Use as the preferred panel to assess and monitor pemphigoid gestationis (herpes gestationis) or other immunobullous disease with complement-fixing basement membrane zone antibodies [ltd.aruplab.com]

Pneumonic Plague

Trop Med Int Health. 2012 Feb;17(2):231-4. doi: 10.1111/j.1365-3156.2011.02905.x. Epub 2011 Nov 1. Abstract Africa reports 90% of human plague cases yet no guidelines currently exist for the safe and accurate collection of sputum from patients with suspected pneumonic plague. Using existing tuberculosis guidelines as a[…] [ncbi.nlm.nih.gov]

Brill-Zinsser Disease

DIFFERENCES IN COMPLEMENT-FIXING ANTIBODIES: HIGH ANTIGEN REQUIREMENT AND HEAT LABILITY. ( 14296293 ) MURRAY E.S....MULAHASANOVIC M. 1965 12 SEROLOGIC STUDIES OF PRIMARY EPIDEMIC [malacards.org]

Differences in Complement-Fixing Antibodies: High Antigen Requirement and Heat Lability J Immunol May 1, 1965, 94 (5) 723-733; Summary Two distinct serologic patterns were [jimmunol.org]

Of 318 Polish refugees now living in this country 30% gave a history of typhus fever; nearly half of these had complement-fixing antibodies to a titre of 1–5 or more to epidemic [doi.org]

Cryoimmunoglobulinemic Syndrome

A significant rise of complement-fixing antibodies to CMV was found during the disease. Cytomegalovirus was isolated from the urine of four patients. [annals.org]

The patients were often positive for immune complexes before complement-fixing antibodies were detectable. [documents.tips]

Coccidioidal Meningitis

The diagnosis is established by the discovery of a high (>1:2) titer of complement-fixing antibody in the cerebrospinal fluid. [ncbi.nlm.nih.gov]

antibody. [ncbi.nlm.nih.gov]

Anti-33-kDa antibodies were detected in 53 (91.4%) of 58 patients whose anti-coccidioidal complement-fixing (CF) antibodies were detectable and in 21 (46.7%) of 45 patients [ncbi.nlm.nih.gov]

Cytomegalovirus Mononucleosis

A significant rise of complement-fixing antibodies to CMV was found during the disease. Cytomegalovirus was isolated from the urine of four patients. [annals.org]

Likewise, a skin rash commonly develops due to a reaction of complement fixing antibodies (for which CMV is responsible) to antibiotics. [symptoma.com]

Abstract After open-heart surgery post-transfusion mononucleosis developed in six patients who had had cytomegalovirus complement-fixing (CMV-CF) antibody before operation [nejm.org]

Histoplasma Pericarditis

All patients demonstrated a fourfold or greater change in complement-fixing antibody titers. [pubmed.ncbi.nlm.nih.gov]

Venezuelan Equine Encephalomyelitis

Hemagglutination-inhibiting, complement-fixing, and neutralizing antibodies were formed by all 13 patients 1 month after illness. [ncbi.nlm.nih.gov]

Complement-fixing antibody was undetectable 11 months after illness in 23% of cases and was detectable at dilutions of 1:8 or 1:6 in 77%. [ncbi.nlm.nih.gov]

Hemagglutination-inhibiting antibody titers were essentially unchanged 11 months after illness. [ncbi.nlm.nih.gov]

Coccidioidomycosis

The majority of the patients had resolution of chest radiograph and coccidiodal complement fixing antibody titers. [ncbi.nlm.nih.gov]

Serological tests showed positive serum for C immitis IgG antibodies with low levels of complement-fixing antibodies (1:2). IgM antibodies were negative. [ncbi.nlm.nih.gov]

Complement-fixing antibody concentration is expressed as a titer, such as 1:4 or 1:64. [ncbi.nlm.nih.gov]

Chronic Pulmonary Blastomycosis

Diagnosis is usually made by direct culture, KOH preparations, special stains, and measurement of complement fixing antibodies to various antigens. [mold-help.org]

Other important tests include KOH preparation, special stains, and measurement of complement fixing antibodies to various antigens (4). [austincc.edu]

Cold Agglutinin Disease

Complement-fixing antibody levels to Mycoplasma pneumoniae, influenza A, and adenoviruses were measured repeatedly throughout the clinical illness and were persistently nondiagnostic [ncbi.nlm.nih.gov]

STRATTON, Complement-Fixing Blood Group Antibodies with Special Reference to the Nature of Anti-Le a, Nature, 10.1038/190240a0, 190, 4772, (240-241), (1961). F. [doi.org]

Of great importance is that the cold agglutinin antibody is able to fix complement when bound to the red cells. [transfusion.ca]

Central Fever

Yellow fever complement-fixing antibody in high titers was found in 18 of 1,201 (1.4%) persons living in eight counties of the affected area. [ajtmh.org]

Necrotizing Alveolitis

Nemir RL, O'Hare D, Goldstein S, Hilton CB (1963) Adenovirus complement-fixing antibody titers from birth through the first year of life: a longitudinal study. [link.springer.com]

Paroxysmal Cold Hemoglobinuria

An IgM complement fixing antibody binds to RBCs at 28-31 o C. The fixed complement causes intravascular hemolysis. [med-ed.virginia.edu]

[…] to be fixed, and then at 37°C for later components of complement to be activated [1,11]. [austinpublishinggroup.com]

[…] hemolyses; antibody elutes from the red cells in vitro, and complement remains fixed, and thus is a 'biphasic' hemolysin; anti-P reacts with normal neutrophil antigens except [medical-dictionary.thefreedictionary.com]

Graft Rejection

The case illustrates the clinical significance of non-complement-fixing anti-HLA antibodies. [ncbi.nlm.nih.gov]

Lucisano Valim YM and Lachmann PJ (1991) The effect of antibody isotype and antigenic epitope density on the complement‐fixing activity of immune complexes: a systematic study [els.net]

It is concluded that screening and cross-matching techniques which detect non-complement-fixing anti-HLA antibodies could improve graft outcome, and should form part of the [ncbi.nlm.nih.gov]

Phlebotomus Fever

Little complement fixing antibody was detected in convalescent sera but most subjects developed significant rises in hemagglutination inhibiting antibodies. [ncbi.nlm.nih.gov]