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11 Possible Causes for Complete Blood Count Abnormal, Globulins Increased, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    A complete blood count (CBC) can detect anemia. A microscopic examination of the blood may reveal the characteristic sickled cells.[] Initial tests recommended include a complete blood count (CBC), electrophoresis at pH 9.2, tests for solubility and sickling, and quantification of Hb A 2 and Hb F.[] A blood test called hemoglobin electrophoresis confirms the diagnosis, by identifying the abnormal form of hemoglobin that is produced in people with the disease.[]

  • Infectious Mononucleosis

    Other tests your doctor might order include a complete blood count (CBC) to see if your blood platelet count is lower than normal and if lymphocytes are abnormal, and a chemistry[] , gamma globulin increased less frequently, and beta globulin, which was normal in practically all the cases of infectious mononucleosis, was increased in a considerable number[] Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[]

  • Hodgkin Lymphoma

    […] cells blood tests, such as a complete blood count (CBC), to measure levels of red blood cells, white blood cells, and platelets immunophenotyping to determine the type of[] Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[] […] following tests may be done: imaging tests, such as X-rays or CT scans lymph node biopsy, which involves removing a piece of lymph node tissue to test for the presence of abnormal[]

  • Precursor-Cell Lymphoblastic Leukemia

    The complete blood count is abnormal . More than 5% of the cells in the bone marrow are blasts ( leukemia cells). There are signs and symptoms of leukemia.[] Late-onset fatal Epstein-Barr virusassociated hemophagocytic syndrome following cord blood cell transplantation for adult acute lymphoblastic leukemia .[] Not all patients with ALL have high white blood cell counts. Even subtle abnormalities on the complete blood count (CBC) may suggest leukemia.[]

  • Hepatitis A

    , which can help increase protection to HAV.[] hemophagocytic syndrome [3].[] […] common Sexual partners and household members of people with HAV If you think you have come in contact with HAV, your doctor may give you a HAV vaccination or a shot of immune globulin[]

  • Erythema Infectiosum

    IV immune globulin has been used to curtail viremia and increase erythropoiesis in immunocompromised patients with pure RBC aplasia.[] Virus-associated hemophagocytic syndrome.[] Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44 : 993 -1002. Rodis, J. F., A. F.[]

  • Exfoliative Dermatitis

    blood count (CBC) Evaluation for cardiac failure Evaluation for intestinal dysfunctions Erythrocyte sedimentation rate or ESR The most commonly detected laboratory abnormalities[] Immune responses may be altered, as evidenced by increased gamma-globulins, increased serum IgE in some cases, eosinophil infiltration, and CD4 T-cell lymphocytopenia in the[] 75 Monoclonal gammopathy of undetermined significance 76 Hemophagocytic histiocytosis, viral associated 78 , 79 Bacterial Tuberculosis 52 Congenital syphilis 57 Viral Hepatitis[]

  • Lymphoma

    A complete blood cell count (CBC) with differential should be obtained, including examination of the peripheral blood smear if the differential is abnormal.[] The erythrocyte sedimentation rate is a sign of activity of the disease and is caused by the increase of the a2-globulins and of the gamma globulins.[] Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[]

  • Pancytopenia

    The doctor will also do a complete blood count (CBC). This test measures the amount of red blood cells, white blood cells, and platelets in your blood.[] […] levels of serum gamma globulin or IgG4; (iii) diffusely irregular narrowing of the main pancreatic duct on ERCP; (iv) fibrotic changes with lymphocyte infiltration on histology[] Virus-associated hemophagocytic syndrome and hemorrhagic jejunal ulcer caused by cytomegalovirus infection in a noncompromised host; a case report of unusual entity.[]

  • Severe Aplastic Anemia

    A doctor can review your blood cell counts from a simple blood test called a complete blood count ( CBC ).[] […] and cyclosporine increased response rates in patients with treatment-naive severe aplastic anemia.[] In virus-associated hemophagocytic syndrome with an acute parvovirus B19 infection, raised levels of cytokines such as interferon γ would impair regulation of the phagocytic[]

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