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18 Possible Causes for Complete Blood Count Abnormal, Hematocrit Decreased, Pernicious Anemia not due to Intrinsic Factor Deficiency

  • Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Pernicious anemia is caused by a lack of intrinsic factor, which is required to absorb vitamin B12 from food.[en.wikipedia.org] Throughout fetal life, erythrocytes decrease in size and increase in number: hematocrit increases from 30% to 40% during the second trimester to 50% to 63% at term.[pedsinreview.aappublications.org]

  • Iron Deficiency Anemia

    Blood sample was collected for complete blood count and ferritin assay.[ncbi.nlm.nih.gov] A vitamin B12 deficiency due to pernicious anemia (positive intrinsic factor antibodies) was also highlighted, but this was not enough to explain the anemia without macrocytosis[ncbi.nlm.nih.gov] ; normal unless infection is present Cells are iron deficient; as hematocrit falls below 30%, hypochromic microcytic cells appear, followed by a decrease in MCV White blood[medical-dictionary.thefreedictionary.com]

  • Pernicious Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Technically, the term "pernicious anemia" refers to vitamin B12 deficiency due to a lack of intrinsic factor.[web.archive.org] […] in serum vitamin B 12 and the decline in hematocrit.[aafp.org]

  • Megaloblastic Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Megaloblastic anemia that arises due to lack of intrinsic factor is called pernicious anemia .[medindia.net] Hematocrit – decreased3. RBC count – decreased/normal4. MCV - 100fl ( normal 82-98fl)5. MCH –increased6. MCHC – NORMAL7. Reticulocytopenia.8.[slideshare.net]

  • Malabsorption Syndrome

    Vitamin B12 (cobalamin) deficiency due to pernicious anemia is caused by a lack of intrinsic factor and by pancreatic enzyme deficiency.[emedicine.medscape.com]

  • Subacute Combined Degeneration of Spinal Cord

    Blood tests that may be ordered include: Complete blood count (CBC) Vitamin B12 blood level Methylmalonic acid blood level Vitamin B12 is given, usually by injection into[nlm.nih.gov] anemia 2016 2017 2018 2019 Billable/Specific Code Applicable To Vegan anemia D51.3 ) pernicious ( ICD-10-CM Diagnosis Code D51.0 Vitamin B12 deficiency anemia due to intrinsic[icd10data.com] Blood tests, including a complete blood count (CBC), vitamin B12 blood level, or methylmalonic acid blood level are used to diagnose anemia or vitamin B12 deficiency.[healthmedicinet.com]

  • Vitamin B12 Deficiency

    When you have an abnormal complete blood count (CBC) with a blood smear showing large red blood cells (macrocytosis) or abnormal (hypersegmented) neutrophils ; when you have[labtestsonline.org] In pernicious anemia, the intrinsic factor necessary for vitamin B12 absorption is lacking, often due to an autoimmune factor.[livestrong.com] […] in serum vitamin B 12 and the decline in hematocrit.[aafp.org]

  • Megaloblastic Anaemia in Pregnancy

    A peripheral smear and a reticulocyte count should be considered if the initial complete blood count is abnormal.[glowm.com] It results in a malignant condition named pernicious anemia due to major vitamin B12 deficiency as the intrinsic factor is responsible for absorbing the vitamin in the intestine[pregmed.org] This accelerates erythropoiesis, but hemoglobin concentration and hematocrit decrease. 3. Iron metabolism In adult men, there is usually little iron loss from the body.[intechopen.com]

  • Posthemorrhagic Anaemia of the Newborn

    Vitamin B12 deficiency anemia due to intrinsic factor deficiency Addison anemia Biermer anemia Pernicious (congenital) anemia Congenital intrinsic factor deficiency D51.1[en.wikisource.org] However, the hematocrit and hemoglobin is decreased. [1] Causes [ edit ] The issue is thought of as representing any of the following: a decreased production of normal-sized[en.wikipedia.org] Monitor hemoglobin, hematocrit, RBC counts, and reticulocyte counts. Decreased RBC indexes are associated with decreased oxygen-carrying capacity of the blood.[nurseslabs.com]

  • Vitamin Deficiency

    , while macrocytosis (high MCV) strongly suggests vitamin B 12 or folic acid deficiency. 5,6 Pernicious anemia (megaloblastic anemia due to failure of the gastric mucosa to[uspharmacist.com] , and erythrocyte count; a decrease in MCV; or an optimal rise in reticulocyte number.[nap.edu] […] secrete adequate and potent intrinsic factor, resulting in malabsorption of vitamin B 12 ) has been reported with increasing frequency, particularly in seniors. 2 Cognitive[uspharmacist.com]