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188 Possible Causes for Complete Blood Count Abnormal, Hypercellular Bone Marrow

  • Chronic Myeloid Leukemia

    The diagnosis of chronic myelogenous leukemia is usually via a blood test called a complete blood count ( CBC ).[] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[] With TKIs, 80 percent of CML patients will have complete disappearance of the Philadelphia chromosome and restoration of normal blood counts.[]

  • Acute Leukemia

    A 1-year-old boy presented with abnormal complete blood count findings, and was found to have blasts and mild dysgranulopoiesis.[] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[] It has not been treated except to relieve signs and symptoms such as fever, bleeding, or pain, and the following are true: The complete blood count is abnormal.[]

  • Polycythemia Vera

    A complete blood cell count reveals a hematocrit of 59% with no other abnormalities. A peripheral blood smear is shown in Figure A.[] bone marrow 5.[] complete blood count (CBC; e.g., Hb 185 g/L in men or 165 g/L in women), but it must be considered in patients with suggestive symptoms.[]

  • Chronic Phase of Chronic Myeloid Leukemia

    Blood Tests : A CBC (complete blood count) may reveal blood cell abnormalities.[] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[] Nearly 20-40% of patients are asymptomatic at presentation, and the diagnosis is only pursued after an abnormal leukocytosis is incidentally noted on complete blood count[]

  • Myeloproliferative Disease

    blood count to examine changes to blood cells, and may also suggest a bone marrow biopsy and aspiration to look for abnormalities.[] The chronic myeloproliferative diseases are characterized by relatively effective hematopoiesis, which results in a hypercellular bone marrow and elevation of one or more[] Blood tests help find abnormal types or numbers of red or white blood cells . They can also detect anemia and leukemia .[]

  • Paroxysmal Nocturnal Hemoglobinuria

    […] smear Complete blood count ( CBC ) Creatinine level Lactate dehydrogenase ( LDH ) level Platelet count Urinalysis Treatment You may have a treatment called plasma exchange[] Bone marrow failure is present in all patients with PNH, even when peripheral blood counts are normal and the bone marrow is hypercellular.[] Concerned with the apparent intravascular hemolysis, a bone marrow biopsy showed hypercellularity and normal cytogenetics.[]

  • Cold Agglutinin Disease

    Diagnosis: In some cases, the diagnosis is made by chance on a standard complete blood count (CBC) detecting abnormal agglutination of the red blood cells .[] Figure 2 Bone marrow biopsy. A. Low magnification (10 x) view of a slightly hypercellular bone marrow with groups (circled) and scattered large lymphoma cells. B.[] In some cases, the diagnosis is first suspected by chance if a routine complete blood count (CBC) detects abnormal clumping (agglutination) of the red blood cells .[]

  • Secondary Polycythemia

    The renal biopsy revealed membranous nephropathy, and the bone marrow biopsy disclosed hypercellular marrow with mild panhyperplasia.[] Bone marrow is hypercellular with prominent megakaryocytes. Serum erythropoietin level is usually low. Blood viscosity is increased.[] Bone marrow normal increased erythropoiesis hypercellular increased erythropoiesis and leucopoiesis 6. leucocyte alkaline phosphatase score normal normal increased in 70%[]

  • Hereditary Spherocytosis

    […] increased Complete blood count to check for anemia Coombs’ test LDH level: Increased Osmotic fragility : This test is widely considered the gold standard for diagnosing hereditary[] Tests may include: Blood smear to show abnormally shaped cells Bilirubin level Complete blood count to check for anemia Coombs test LDH level Osmotic fragility or specialized[] Tests may include: Blood smear to show abnormally shaped cells (the red blood cells will appear abnormally small and lack the central pallor) Bilirubin level: indirect Bilirubin[]

  • Cooley's Anemia

    Blood tests Peripheral blood smear shows small, abnormally-shaped red blood cells Complete blood count shows anemia Haemoglobin electrophoresis shows abnormal hemoglobin Prognosis[] A complete blood count (CBC) identifies anemia, while smaller than average red blood cells and other abnormalities that are characteristic of the blood disorder can be viewed[] Diagnosis: Cooley's anemia is diagnosed using blood tests.[]

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