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158 Possible Causes for Complete Blood Count Abnormal, Hypercellular Bone Marrow

  • Leukemia

    blood count to check for abnormalities in your white blood cell, hemoglobin, and platelet levels.[rd.com] Bone marrow aspirate showed hypercellularity with increased myelopoiesis and markedly suppressed megakaryopoiesis giving an impression of acute myeloid leukemia and was confirmed[ncbi.nlm.nih.gov] Another important feature of bone marrow samples is its cellularity. Normal bone marrow contains hematopoietic (blood-forming) cells and fat cells.[web.archive.org]

  • Hereditary Spherocytosis

    […] increased Complete blood count to check for anemia Coombs’ test LDH level: Increased Osmotic fragility : This test is widely considered the gold standard for diagnosing hereditary[medical-labs.net] Tests may include: Blood smear to show abnormally shaped cells Bilirubin level Complete blood count to check for anemia Coombs test LDH level Osmotic fragility or specialized[mountsinai.org] All patients underwent clinical and physical evaluation and the following laboratory tests: complete blood counts, blood smear examination, reticulocyte count, assays of bilirubin[doi.org]

  • Myeloproliferative Disease

    blood count to examine changes to blood cells, and may also suggest a bone marrow biopsy and aspiration to look for abnormalities.[mountsinai.org] Bone marrow histology shows hypercellularity in most of these disorders. In the case of myelofibrosis, bone marrow fibrosis is demonstrated on the reticulin stain.[emedicine.com] Blood tests help find abnormal types or numbers of red or white blood cells . They can also detect anemia and leukemia .[diagnose-me.com]

  • Pernicious Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Even in patients with a normal complete blood cell count, it may be worthwhile to monitor the MCV after treatment because a significant decline within the normal range provides[doi.org] Laboratory Tests The initial test for anemia, the complete blood count (CBC), may reveal many abnormal results. Hemoglobin and/or hematocrit may be low.[labtestsonline.org]

  • Chronic Myeloid Leukemia

    Blood tests Chromosome analysis The diagnosis of CML is suspected when the results of a complete blood count show an abnormally high white blood cell count.[merck.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] The diagnosis of chronic myelogenous leukemia is usually via a blood test called a complete blood count ( CBC ).[medicinenet.com]

  • Autoimmune Hemolytic Anemia

    Often, anemia caused by chronic diseases goes undetected until a routine test such as a complete blood count (CBC) reveals abnormal results.[labtestsonline.org] Subsequently, the patient underwent a bone marrow biopsy that showed a hypercellular marrow with erythroid hyperplasia, but no evidence of dysplasia or lymphoma.[doi.org] Inwards, How to Interpret and Pursue an Abnormal Complete Blood Cell Count in Adults, Mayo Clinic Proceedings, 80, 7, (923), (2005). D. Stahl and W.[doi.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    Blood Tests : A CBC (complete blood count) may reveal blood cell abnormalities.[knowcancer.com] marrow biopsy: Moderately hypercellular bone marrow biopsy with numerous megakaryocytes Increased reticulin fibers (reticulin stain) Marked hypercellularity Myeloblastic[pathologyoutlines.com] Nearly 20-40% of patients are asymptomatic at presentation, and the diagnosis is only pursued after an abnormal leukocytosis is incidentally noted on complete blood count[clinicaladvisor.com]

  • Polycythemia Vera

    complete blood count (CBC; e.g., Hb 185 g/L in men or 165 g/L in women), but it must be considered in patients with suggestive symptoms.[mpncanada.com] bone marrow 5.[slideshare.net] Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.[ncbi.nlm.nih.gov]

  • Acute Leukemia

    A 1-year-old boy presented with abnormal complete blood count findings, and was found to have blasts and mild dysgranulopoiesis.[ncbi.nlm.nih.gov] ALL : Hypercellular bone marrow Numerous tightly packed lymphoblasts with undetectable cytoplasm, round, irregular, cleaved nuclei, dispersed chromatin, small nucleoli B[pathologyoutlines.com] Chronic Myeloid Leukemia (CML) Chronic myeloid leukemia is most often suspected before any symptoms are present when the results of a complete blood count (CBC) are abnormal[verywellhealth.com]

  • Paroxysmal Nocturnal Hemoglobinuria

    These patients tend to have a normocellular to hypercellular bone marrow with erythroid hyperplasia, an elevated reticulocyte count, a large population of PNH cells (usually[doi.org] Thrombosis is the leading cause of death, but others may die of complications of bone marrow failure, renal failure, myelodysplastic syndrome, and leukemia.[doi.org]

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