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99 Possible Causes for Complete Blood Count Abnormal, Massive Splenomegaly, Pancytopenia

  • Leukemia

    blood count to check for abnormalities in your white blood cell, hemoglobin, and platelet levels.[rd.com] Splenomegaly can be massive, consistency high, with the fibrous thickening of the capsule.[ncbi.nlm.nih.gov] This fact sheet discusses the theory that intermittent fasting may reduce the risk of cancer or improve outcomes with anticancer treatments. more » A 47-Year-Old Woman with Pancytopenia[cancertherapyadvisor.com]

  • Primary Myelofibrosis

    She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[ncbi.nlm.nih.gov] Primary myelofibrosis is diagnosed using the following procedures: Blood testing: Complete blood count (CBC) looking for abnormal amounts of red and white blood cells and[patientworthy.com] This is then followed by pancytopenia (a reduction in the number of red and white blood cells, as well as platelets).[aoporphan.com]

  • Chronic Lymphocytic Leukemia

    Blood tests that may be used to confirm a diagnosis of CLL include: [7] Complete blood count - people with CLL have too many lymphocytes (called lymphocytosis ).[rarediseases.info.nih.gov] splenomegaly and occasionally lymphadenopathy; prognosis is often poor.[medical-dictionary.thefreedictionary.com] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    The diagnosis of HCL may be suggested by abnormal results on a complete blood count (CBC), but additional testing is necessary to confirm the diagnosis.[en.wikipedia.org] Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] We should keep in mind other reasons for vasculitis such as lymphoproliferative disease, especially whose who have hematological abnormalities such as pancytopenia.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Blood tests Chromosome analysis The diagnosis of CML is suspected when the results of a complete blood count show an abnormally high white blood cell count.[merck.com] Chronic myeloid leukemia (CML) is a chronic myeloproliferative disorder that usually presents with high white blood cell counts and massive splenomegaly.[ncbi.nlm.nih.gov] We present a case of 29-year-old white male farmer, with chronic myeloid leukemia treated with imatinib who developed significant pancytopenia, leading to discontinuation[ncbi.nlm.nih.gov]

  • Paroxysmal Nocturnal Hemoglobinuria

    We describe a patient under treatment with the anti-complement antibody eculizumab who developed pancytopenia, requiring blood transfusions, due to massive splenomegaly.[ncbi.nlm.nih.gov] We report a 19-year-old female patient admitted to the hospital with pancytopenia. Workout of pancytopenia disclosed paroxysmal nocturnal hemoglobinuria.[ncbi.nlm.nih.gov] Other features include weakness, abdominal and lumbar pain, jaundice with pallor and yellowish discoloration of the skin and mucous membranes, heart murmurs, splenomegaly,[whonamedit.com]

  • Myeloproliferative Disease

    blood count to examine changes to blood cells, and may also suggest a bone marrow biopsy and aspiration to look for abnormalities.[mountsinai.org] Four years later, at the age of 16, her brother was diagnosed as having acute myelofibrosis, and some months afterwards he died from fulminant pneumonia coincidently with pancytopenia[ncbi.nlm.nih.gov] ( D61.82 ) pancytopenia (due to) (with) congenital (pure) red cell aplasia ( D61.01 ) pancytopenia (due to) (with) hairy cell leukemia ( C91.4- ) pancytopenia (due to) (with[icd10data.com]

  • Hypersplenism

    CONCLUSION: Our results demonstrate that shunt surgery with partial resection of the spleen is effective and safe for pediatric patients with massive splenomegaly and severe[ncbi.nlm.nih.gov] Hypersplenism should be considered in patients with persistent or recurrent pancytopenia and splenomegaly post-transplantation.[ncbi.nlm.nih.gov] Apart from a strongly positive Mantoux test, all investigations for massive splenomegaly proved negative.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Blood Tests : A CBC (complete blood count) may reveal blood cell abnormalities.[knowcancer.com] Nearly 20-40% of patients are asymptomatic at presentation, and the diagnosis is only pursued after an abnormal leukocytosis is incidentally noted on complete blood count[clinicaladvisor.com] If this is the case, a complete blood count (CBC) will be conducted. This test can provide a more detailed account of the abnormalities in the blood cells.[rarediseases.org]

  • Visceral Leishmaniasis

    He had massive splenomegaly. His cardiovascular, respiratory and neurological examination were normal.[ncbi.nlm.nih.gov] We present an unusual case of febrile pancytopenia in a nonagenarian who was diagnosed with visceral leishmaniasis.[ncbi.nlm.nih.gov] ., infection with Leishmania sp. associated with high fever, weight loss, massive splenomegaly and markedly altered laboratory parameters, is generally fatal if untreated.[ncbi.nlm.nih.gov]

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