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41 Possible Causes for Complete Blood Count Abnormal, Severe Peripheral Motor Neuropathy

  • Chronic Kidney Insufficiency

    , peripheral sensory and motor neuropathies, muscle cramps, hyperreflexia, restless legs syndrome, and seizures (usually the result of hypertensive or metabolic encephalopathy[merckmanuals.com] With more severe renal disease (eg, estimated glomerular filtration rate [eGFR] 15 mL/min/1.73 m 2 ), neuromuscular symptoms may be present, including coarse muscular twitches[merckmanuals.com]

  • Oculomotor Apraxia

    Investigations included complete blood count, serum electrolytes including calcium, magnesium, phosphorus, liver function tests, and a complete thyroid panel.[annalsofian.org] […] primary motor peripheral axonal motor neuropathy.[ncbi.nlm.nih.gov] motor handicap Severe peripheral neuropathy developing with the course of the disease Absence of extra-neurologic findings common in ataxia-telangiectasia Long survival Family[centogene.com]

  • Megaloblastic Anaemia in Pregnancy

    A peripheral smear and a reticulocyte count should be considered if the initial complete blood count is abnormal.[glowm.com] Patients with a severe deficiency can present with peripheral neuropathy, motor disturbances, visual disturbances and cognitive changes ranging from memory loss to dementia[bpac.org.nz] Additional tests may be used for confirming the diagnosis and differentiating it from other conditions with similar symptoms [11] : Peripheral blood smear [16] Complete blood[pregmed.org]

  • Immune Thrombocytopenic Purpura

    A complete blood count shows thrombocytopenia and low hemoglobin suggests anemia due to blood loss.[symptoma.com] Multiple variants of GBS exist, with acute motor and sensory axonal neuropathy (AMSAN) being the most severe.[ncbi.nlm.nih.gov] Complete blood count reveals a platelet count of 8 10 9 /L and is otherwise normal. Peripheral blood smear shows a few large platelets and no other abnormalities. 1.1.[doi.org]

  • Porphyria

    Acute attacks occur mainly in adults and comprise severe abdominal pain, nausea, vomiting, autonomic disturbance, central nervous system involvement and peripheral motor neuropathy[ncbi.nlm.nih.gov] The most severe episodes may involve neurological complications: typically motor neuropathy (severe dysfunction of the peripheral nerves that innervate muscle), which leads[en.wikipedia.org] […] urine), peripheral neuropathy (patchy numbness and paresthesias), Proximal motor weakness (usually starting in upper extremities which can progress to include respiratory[house.wikia.com]

  • Malabsorption Syndrome

    Other possible symptoms due to nutrient deficiencies include motor weakness (pantothenic acid), peripheral neuropathy (thiamine), a sense of loss (cobalamin), night blindness[symptoma.com] Very severe might also be electrolyte deficiencies, like hypocalcemia and hypomagnesaemia, which frequently lead to tetany.[symptoma.com]

  • Acute Hepatic Porphyria

    […] urine), peripheral neuropathy (patchy numbness and paresthesias), Proximal motor weakness (usually starting in upper extremities which can progress to include respiratory[house.wikia.com] They include abdominal pain which is severe and poorly localized (most common, 95% of patients experience), Urinary symptoms (Dysuria, urinary retention/incontinence or dark[house.wikia.com]

  • Churg-Strauss Syndrome

    The majority of these cases (7/11) had sensory–motor mononeuritis multiplex neuropathy.[doi.org] Eleven of 19 (57.8%) patients showed signs of peripheral nerve involvement (Table 1 ).[doi.org] Two of the patients (AA, FA) demonstrated severe functional impairment and cranial nerve involvement (facial palsy).[doi.org]

  • Acute Intermittent Porphyria

    Acute attacks are characterized by severe abdominal pain, vomiting, constipation, hypertension, tachycardia, and bladder dysfunction, presumably due to an autonomic neuropathy[doi.org] […] urine), peripheral neuropathy (patchy numbness and paresthesias), Proximal motor weakness (usually starting in upper extremities which can progress to include respiratory[house.wikia.com] Motor weakness and sensory involvement presumably result from the peripheral axonal neuropathy, and mental symptoms do not have clear cerebral morphological findings. 1 Although[doi.org]

  • Castleman Disease

    CONCLUSION: There is a spectrum of demyelinating peripheral neuropathies associated with Castleman disease.[ncbi.nlm.nih.gov] CD-PN is sensory predominant and is the mildest phenotype, whereas CD-POEMS is a more severe sensory and motor neuropathy.[ncbi.nlm.nih.gov]

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