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109 Possible Causes for Congenital Hemolytic Anemia, Hematocrit Decreased, Reticulocytes Increased

  • Hereditary Spherocytosis

    Reticulocyte count: Increased Treatment: Splenectomy is indicated for moderate to severe cases, but not mild cases.[medical-labs.net] […] biconcave disk shape Congenital spherocytic hemolytic anemia Minkowski Chauffard syndrome spherocytic anemia edit English hereditary spherocytosis congenital hemolytic anemia[wikidata.org] A complete blood count (CBC) may show increased reticulocytes, a sign of increased red blood cell production, and decreased hemoglobin and hematocrit.[en.wikipedia.org]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] […] from congenital hemolytic anemia.[en.wikipedia.org] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Cooley's Anemia

    Children may develop dramatic, often life threatening drops in hematocrit with reticulocyte counts of nearly zero.[de.slideshare.net] , Hemolytic, Congenital Anemia, Hemolytic Hemoglobinopathies Genetic Diseases, Inborn Iron Metabolism Disorders Lung Diseases Respiratory Tract Diseases Sildenafil Citrate[clinicaltrials.gov] The differential white blood count shows a decrease in most types of cells but not lymphocytes .[labtestsonline.org]

  • Pyruvate Kinase Deficiency

    Char10C mice also display a reduction in anemia phenotypes associated with the PklrG338D mutation including decreased splenomegaly, decreased circulating reticulocytes, increased[ncbi.nlm.nih.gov] HEREDITARY spherocytosis with its associated congenital hemolytic anemia is generally easily recognized and satisfactorily treated with splenectomy.[nejm.org] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Sickle Cell Disease

    With each course, fetal reticulocytes increased within 48-72 h, peaked in 7-11 d, and fell by 18-21 d.[doi.org] (p 0.001), while hemoglobin and hematocrit remained stable.[ncbi.nlm.nih.gov] On her third day of admission, due to hemoglobin (Hb) value of 6.9 g/dL with increase in reticulocytes, the patient was transfused with one unit of compatible leukodepleted[ncbi.nlm.nih.gov]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] Congenital hemolytic anemia refers to hemolytic anemia which is primarily due to congenital disorders.[en.wikipedia.org] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Hereditary Elliptocytosis

    His hemoglobin is now practically normal, but he still has a slight but persistent reticulocyte increase.[pediatrics.aappublications.org] Hereditary pyropoikilocytosis (HPP) is a severe, congenital hemolytic anemia occurring almost exclusively in black persons and characterized by extreme red blood cell anisopoikilocytosis[ncbi.nlm.nih.gov] Post-splenectomy, patients with HE or HPP exhibit increased hematocrit, decreased reticulocyte counts, and improved clinical symptoms.[cancertherapyadvisor.com]

  • Glycogen Storage Disease Type 1

    Pyrimidine 5' nucleotidase deficiency presents with congenital hemolytic anemia because the residual nucleotides in young red cells (reticulocytes) cannot be metabolized and[cancertherapyadvisor.com] […] adrenal hyperplasia ( E25.0 ) Ehlers-Danlos syndrome ( Q79.6 ) hemolytic anemias attributable to enzyme disorders ( D55.- ) Marfan's syndrome ( Q87.4 ) 5-alpha-reductase[icd10data.com] Pyruvate kinase deficiency is the most common glycolytic enzyme deficiency that leads to life-long hemolytic anemia.[cancertherapyadvisor.com]

  • Congenital Dyserythropoietic Anemia

    On this treatment, hemoglobin and reticulocytes increased and transfusions became unnecessary.[ncbi.nlm.nih.gov] She has long been diagnosed with unclassified congenital hemolytic anemia from the neonatal period.[ncbi.nlm.nih.gov] Following delivery the infant had serial blood counts performed over a 6-week period, which noted a steady decrease in her hematocrit to 16%.[bloodjournal.org]

  • Hypersplenism

    Normocytic, normochromic anemia Reticulocytes increased Increased MCV is due to prominent reticulocytosis Spherocytes Bone marrow Hypercellular with erythroid precursors[5minuteconsult.com] Indications for Splenectomy Splenectomy always indicated Primary tumor (rare) Hereditary spherocytosis (congenital hemolytic anemia) Splenectomy usually indicated Splenic[for-surgeons.com] […] in red cell production usually is evident by an increase in the reticulocyte count.[medtextfree.wordpress.com]

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