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294 Possible Causes for Congenital Leptin Deficiency

  • Acquired Generalized Lipodystrophy

    leptin deficiency are allergic to metreleptin or any of the ingredients in Myalept.[myalept.com] CONTRAINDICATIONS: MYALEPT is contraindicated in general obesity not associated with congenital leptin deficiency.[myaleptpro.com] leptin deficiency.[astrazeneca-us.com]

  • Obesity

    Here we report a unique case with congenital leptin deficiency.[ncbi.nlm.nih.gov] congenital leptin deficiency.[doi.org] Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387, 903–908 (1997).[doi.org]

  • Metabolic Syndrome

    leptin deficiency is associated with severe early-onset obesity in humans.[doi.org] Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med. 1999; 341 :879–884. [ PubMed ] [ Google Scholar ] 120.[ncbi.nlm.nih.gov] Farroqi, S, Whitehead, J, Soos, M, Rau, H, Wareham, N, Sewter, C, Digby, J, Mohammed, S, Hurst, J, Cheetham, C, Earley, A, Barnett, A, Prins, J &, O'Rahilly, S ( 1997 ) Congenital[doi.org]

  • Insulin Resistance

    Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 387, 903– 908 (1997). 14 Pelleymounter, M. A. et al.[doi.org] Congenital leptin deficiency is associated with severe early-onset obesity in humans.[doi.org] Science. 269 : 540 – 543. 5, et al. 1997 Congenital leptin deficiency is associated with severe early-onset obesity in humans.[doi.org]

  • Generalized Lipodystrophy

    CONTRAINDICATIONS: MYALEPT is contraindicated in general obesity not associated with congenital leptin deficiency.[myaleptpro.com] CONTRAINDICATIONS MYALEPT (metreleptin for injection) is contraindicated in patients with: General obesity not associated with congenital leptin deficiency.[novelion.com] Congenital generalized lipodystrophy is a rare disorder characterized by scant adipose tissue, profound leptin deficiency, and severe insulin resistance, resulting in multiple[ncbi.nlm.nih.gov]

  • Lipodystrophy

    CONTRAINDICATIONS: MYALEPT is contraindicated in general obesity not associated with congenital leptin deficiency.[myaleptpro.com] CONTRAINDICATIONS MYALEPT (metreleptin for injection) is contraindicated in patients with: General obesity not associated with congenital leptin deficiency.[novelion.com] Effects of recombinant leptin therapy in a child with congenital leptin deficiency. N Engl J Med 1999 ;341: 879 - 884 6. Reitman ML, Arioglu E, Gavrilova O, Taylor SI.[doi.org]

  • Familial Hypercholesterolemia

    , X-Linked 2 Obesity 3 Obesity, Morbid, Due to Leptin Deficiency 6 Obesity, Morbid, Due to Leptin Receptor Deficiency 6 Obsessive-Compulsive Disorder 1 Occipital Horn Syndrome[preventiongenetics.com] Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia 4 Noonan-Like Syndrome With Loose Anagen Hair 4 Norrie Disease 4 Norum Disease 1 Nystagmus 6, Congenital[preventiongenetics.com]

  • Thyroid Cancer

    Congenital lack of leptin does not affect the correct development of a normal hypothalamus–pituitary–thyroid axis, and in leptin-deficient patients it is unclear whether and[web.archive.org]

  • Dilated Cardiomyopathy Type 2B

    , X-Linked 2 Obesity 3 Obesity, Morbid, Due to Leptin Deficiency 6 Obesity, Morbid, Due to Leptin Receptor Deficiency 6 Obsessive-Compulsive Disorder 1 Occipital Horn Syndrome[preventiongenetics.com] Noonan Syndrome-Like Disorder With Or Without Juvenile Myelomonocytic Leukemia 4 Noonan-Like Syndrome With Loose Anagen Hair 4 Norrie Disease 4 Norum Disease 1 Nystagmus 6, Congenital[preventiongenetics.com]

  • Hypogonadotropic Hypogonadism Type 8

    Montague CT, Farooqi S, Whitehead FP et al (1997) Congenital leptin deficiency is associated with severe early-onset obesity in humans.[link.springer.com]

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