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67 Possible Causes for Congenital Nonspherocytic Hemolytic Anemia, Erythrocytes Decreased, Fever

  • Hereditary Spherocytosis

    Defects in these proteins lead to a loss in RBC membrane cohesion and membrane surface area, resulting in erythrocyte sphering, decreased deformability and premature destruction[orpha.net] A 33-year-old woman with hereditary spherocytosis and gallstones was admitted because of rapid progress in marked anemia and fever.[ncbi.nlm.nih.gov] Stability studies with blood from HS patients showed a significant decrease in hyperchromic erythrocytes after 6 h storage.[ncbi.nlm.nih.gov]

  • Autoimmune Hemolytic Anemia

    Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] A 7-month-old boy, presented with prolonged fever, erythematous rash, severe pallor and hepatosplenomegaly.[ncbi.nlm.nih.gov] Infectious mononucleosis is one of the main manifestations of Epstein - Barr virus, which is characterized by fever, tonsillar-pharyngitis, lymphadenopathy and atypical lymphocytes[ncbi.nlm.nih.gov]

  • Glycogen Storage Disease Type 1

    Phk activity in erythrocytes was markedly decreased (12% residual activity) while the parents' erythrocyte Phk activities were in the heterozygote range (mother: 56%; father[academic.oup.com] ; FMF Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent attacks of fever and inflammation in the peritoneum, synovium, or pleura[mendelian.co] […] polydystrophy - Aspartylglucosaminuria - Fucosidosis - Alpha-mannosidosis - Sialidosis Other Alpha 1-antitrypsin deficiency - Cystic fibrosis - Amyloidosis ( Familial Mediterranean fever[wikidoc.org]

  • Congenital Hemolytic Anemia

    Phosphatidylserine internalization in erythrocytes with the mutant ATP11C was decreased 10-fold compared to that of the control, functionally establishing that ATP11C is a[ncbi.nlm.nih.gov] This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding[en.wikipedia.org] One month before admission, he had been treated with phenytoin and valproate after a seizure episode without fever.[casesjournal.biomedcentral.com]

  • Pyruvate Kinase Deficiency

    decreased erythrocyte pyruvate kinase (PK) activity.[ncbi.nlm.nih.gov] In this later group of "congenital nonspherocytic hemolytic anemias" splenectomy has often been performed but usually does not produce a clinical cure.[nejm.org] Congenital insensitivity to pain with anhidrosis is an autosomal recessive hereditary disorder characterized by recurrent episodic fever, anhidrosis (inability to sweat),[ncbi.nlm.nih.gov]

  • Acquired Toxic Hemolytic Anemia

    Premature destruction of red cells occurs through two primary mechanisms: (1) decreased erythrocyte deformability that leads to red-cell sequestration and extravascular haemolysis[oxfordmedicine.com] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[diagnose-me.com] Symptoms such as fever are prominent among infections such as malaria, babesiosis, C. perfringens and B. bacilliformis (Oroya fever).[clinicaladvisor.com]

  • Traumatic Hemolytic Anemia

    […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] In a cquired hemolytic anemia, the presentation may be acute with acute febrile illness such as fever, body aches, malaise, vomiting, etc.[medcaretips.com] Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hereditary.[aafp.org]

  • Toxic Hemolytic Anemia

    […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] Symptoms such as fever are prominent among infections such as malaria, babesiosis, C. perfringens and B. bacilliformis (Oroya fever).[clinicaladvisor.com] Severe hemolytic anemia can cause chills, fever, pain in the back and abdomen, or shock.[nhlbi.nih.gov]

  • Hypersplenism

    As a disorder, hypersplenism typically involves a distended spleen (splenomegaly), decreased levels of leukocytes, erythrocytes and platelets, shorter platelet and erythrocyte[symptoma.com] […] abscess (rare) Splenectomy sometimes indicated Elliptocytosis with hemolysis Nonspherocytic congenital hemolytic anemias Hodgkin’s disease (for staging) Idiopathic myelofibrosis[for-surgeons.com] A 9-year-old girl with a 5-6-month history of abdominal distension and fever was found to have massive splenomegaly with features of hypersplenism.[ncbi.nlm.nih.gov]

  • Congenital Aplastic Anemia

    Discussion Aplastic anemia are disorders where there is inadequate production of erythrocytes, granulocytes and platelets caused by decreased bone marrow production leading[pediatriceducation.org] nonspherocytic hemolytic anemia * (n) 先天性貧血 P614 ** せんてんせいひんけつ PubMed, Scholar, Google, WikiPedia congenital anemia * (n*) 先天性溶血性貧血 *** せんてんせいようけつせいひんけつ シソーラス PubMed, Scholar[lsd-project.jp] Usually, the person will be kept under observation unless a fever develops that lasts for more than two hours, in which case antibiotics will be given.[healthery.com]

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