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57 Possible Causes for Congenital Nonspherocytic Hemolytic Anemia, Erythrocytes Decreased, Hemoglobinuria

  • Autoimmune Hemolytic Anemia

    March hemoglobinuria Paroxysmal cold hemoglobinuria Type 1 Excludes hemoglobinuria NOS ( R82.3 ) Use Additional code (Chapter 20) to identify external cause D59.6 ) The following[icd10data.com] Mechanisms of actions include suppression of autoantibody production, reduction in autoantibody affinity, and decreased destruction of erythrocytes by splenic macrophages,[doi.org] In patients with Evans syndrome, the mechanism of destruction of erythrocytes is thought to be similar to AIHA.[cancertherapyadvisor.com]

  • Glycogen Storage Disease Type 1

    Phk activity in erythrocytes was markedly decreased (12% residual activity) while the parents' erythrocyte Phk activities were in the heterozygote range (mother: 56%; father[academic.oup.com] Chronic hepatitis Albuminuria Distal renal tubular acidosis Hepatocellular adenoma Hypocitraturia Cataract Hyperreflexia Gait disturbance Full cheeks Carcinoma Elevated erythrocyte[mendelian.co] […] hypoplastic anemia Hyperkalemia Inflammation of the large intestine Intestinal obstruction Episodic fever Amyloidosis Antinuclear antibody positivity Acute hepatic failure Decreased[mendelian.co]

  • Congenital Hemolytic Anemia

    Acquired membranopathies a) paroxysmal nocturnal hemoglobinuria b) spore cell anemia 3.[en.medicine-guidebook.com] Phosphatidylserine internalization in erythrocytes with the mutant ATP11C was decreased 10-fold compared to that of the control, functionally establishing that ATP11C is a[ncbi.nlm.nih.gov] This group is sometimes called congenital nonspherocytic (hemolytic) anemia, which is a term for a congenital hemolytic anemia without spherocytosis, and usually excluding[en.wikipedia.org]

  • Toxic Hemolytic Anemia

    In acute toxic hemolytic anemia, intravascular hemolysis arises, manifested by hemoglobinemia, hemoglobinuria, and sometimes accompanied by collapse and anuria.[m.iliveok.com] […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] [Marchiafava-Micheli] D59.6 Hemoglobinuria due to hemolysis from other external causes Inclusion term(s): Hemoglobinuria from exertion March hemoglobinuria Paroxysmal cold[icd10coded.com]

  • Hereditary Spherocytosis

    […] usually mild; treatment is splenectomy Includes hereditary erythrocyte membrane defects, enzyme deficiencies, hemoglobin abnormalities, stem cell defects (paroxysmal nocturnal hemoglobinuria[icd9data.com] Defects in these proteins lead to a loss in RBC membrane cohesion and membrane surface area, resulting in erythrocyte sphering, decreased deformability and premature destruction[orpha.net] Additionally, daily oral penicillin prophylaxis for 3-5 years afterwards Differential Diagnosis : 1) Autoimmune hemolytic anemia (negative family history) 2) Paroxysmal nocturnal hemoglobinuria[medlibes.com]

  • Traumatic Hemolytic Anemia

    Hemoglobinuria has also been ...[mhmedical.com] […] and the inability of bone marrow to compensate for the decreased life span.[diagnose-me.com] Premature destruction of erythrocytes occurs intravascularly or extravascularly. The etiologies of hemolysis often are categorized as acquired or hereditary.[aafp.org]

  • Acquired Toxic Hemolytic Anemia

    [Marchiafava-Micheli] D59.6 Hemoglobinuria due to hemolysis from other external causes Inclusion term(s): Hemoglobinuria from exertion March hemoglobinuria Paroxysmal cold[icd10coded.com] Premature destruction of red cells occurs through two primary mechanisms: (1) decreased erythrocyte deformability that leads to red-cell sequestration and extravascular haemolysis[oxfordmedicine.com] Congenital Nonspherocytic Hemolytic Anemia includes any of a group of inherited anemias characterized by shortened red cell survival, lack of spherocytosis, and normal osmotic[diagnose-me.com]

  • Pyruvate Kinase Deficiency

    Among the diagnoses to be considered are paroxysmal cold hemoglobinuria, favism, march hemoglobinuria, black water fever, congenital hemolytic icterus and toxic hemoglobinuria[kundoc.com] decreased erythrocyte pyruvate kinase (PK) activity.[ncbi.nlm.nih.gov] In this later group of "congenital nonspherocytic hemolytic anemias" splenectomy has often been performed but usually does not produce a clinical cure.[nejm.org]

  • Fetal Erythroblastosis

    If the red color is due to hemoglobinuria, the urine sample remains clear red after centrifugation.[emedicine.medscape.com] The phenotype of severe nonspherocytic hemolytic anemia, jaundice, hepatosplenomegaly, and marked erythroblastosis is more severe than that present in congenital dyserythropoietic[readbyqxmd.com] The first clinical signs of these delayed reactions, which include dark urine/hemoglobinuria, appear a median of 9.4 days after the triggering transfusion.[emedicine.medscape.com]

  • Congenital Aplastic Anemia

    Paroxysmal nocturnal hemoglobinuria can lead to aplastic anemia, or aplastic anemia can evolve into paroxysmal nocturnal hemoglobinuria.[mayoclinic.org] Discussion Aplastic anemia are disorders where there is inadequate production of erythrocytes, granulocytes and platelets caused by decreased bone marrow production leading[pediatriceducation.org] nonspherocytic hemolytic anemia * (n) 先天性貧血 P614 ** せんてんせいひんけつ PubMed, Scholar, Google, WikiPedia congenital anemia * (n*) 先天性溶血性貧血 *** せんてんせいようけつせいひんけつ シソーラス PubMed, Scholar[lsd-project.jp]

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