Create issue ticket

3,493 Possible Causes for Congenital Onset, Psychomotor Development Profoundly Delayed, Wide Space Between the First and Second Toe

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] liver - See Nodular regenerative hyperplasia Nodulosis arthropathy osteolysis syndrome - See Torg Winchester syndrome Noma Noma neonatorum - See Noma NOMID - See Neonatal Onset[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Amish Lethal Microcephaly

    delayed psychomotor development, brain malformations, and episodic encephalopathy associated with lactic acidosis, alpha-ketoglutaric aciduria and death within the first[medical-dictionary.thefreedictionary.com] onset Symptoms present at birth 0003577 Flexion contracture Flexed joint that cannot be straightened 0001371 Lactic acidosis Increased lactate in body 0003128 Muscular hypotonia[rarediseases.info.nih.gov] Get Update Overview Amish type microcephaly is a severe autosomal recessive metabolic disorder characterized by severe microcephaly apparent at birth, profoundly delayed psychomotor[diseaseinfosearch.org]

    Missing: Wide Space Between the First and Second Toe
  • Pontocerebellar Hypoplasia Type 4
    Missing: Wide Space Between the First and Second Toe
  • Pontocerebellar Hypoplasia Type 10
    Missing: Wide Space Between the First and Second Toe
  • Autosomal Recessive Microcephaly with Chorioretinopathy Type 2
    Missing: Wide Space Between the First and Second Toe
  • Down Syndrome

    Alzheimer’s and auto-immune diseases, and they are more likely to suffer from congenital heart defects.[denverpost.com] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[dx.doi.org]

    Missing: Psychomotor Development Profoundly Delayed
  • Dubowitz Syndrome

    1 Split hand foot malformation 1 Multiple epiphyseal dysplasia 5 Keratosis follicularis dwarfism and cerebral atrophy Giant congenital nevus Vein of Galen aneurysm Refsum[checkrare.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Type i (classical; csa) is early childhood onset in the second year of life; type ii (congenital; csb) is early onset at birth with severe symptoms; type iii (xeroderma pigmentosum[icd10data.com]

    Missing: Psychomotor Development Profoundly Delayed
  • Ring Chromosome 10

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Congenital heart disease and genitourinary anomalies were reported in some cases.[orpha.net] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Psychomotor Development Profoundly Delayed
  • Arterial Tortuosity Syndrome

    […] diaphragmatic hernia 0000776 Congenital onset Symptoms present at birth 0003577 Convex nasal ridge Beaked nose Beaklike protrusion Hooked nose Polly beak nasal deformity[rarediseases.info.nih.gov] She had a history of congenital rectal prolapse, colonic diverticulosis, and iron deficiency anemia.[neurology.org] TAAD has a highly variable age of onset and presentation, and may involve additional features such as congenital heart defects and other features of connective tissue disease[mayomedicallaboratories.com]

    Missing: Psychomotor Development Profoundly Delayed Wide Space Between the First and Second Toe
  • Atelosteogenesis Type 2

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Information on several of them, including congenital spondyloepiphyseal dysplasia, multiple epiphyseal dysplasia, pseudoachondroplasia and late-onset spondyloepiphyseal dysplasia[socialstyrelsen.se] Hepatic, Type IA Carnitine Palmitoyltransferase II Deficiency Carnitine Palmitoyltransferase II Deficiency, Infantile Carnitine Palmitoyltransferase II Deficiency, Late-onset[sequencing.com]

    Missing: Psychomotor Development Profoundly Delayed

Similar symptoms