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122 Possible Causes for Congenital Pain Insensitivity, Heat Intolerance

  • Autonomic Neuropathy

    The symptoms depend upon what organs are affected and may include abdominal swelling, heat intolerance, nausea, vomiting, impotence, diarrhea , constipation , dizziness with[medicinenet.com] Abstract Congenital insensitivity (HSAN) to pain is a rare disorder, which affects the body's painprotective mechanism and predisposes the patient to increased risk and incidence[ncbi.nlm.nih.gov] Symptoms of Autonomic Neuropathy General symptoms of this condition may include: Inability to sweat properly, leading to heat intolerance Loss of bladder control, leading[stanfordhealthcare.org]

  • Primary Progressive Multiple Sclerosis

    先天性無痛無汗症 Congenital insensitivity to pain with anhidrosis 無痛無汗症 1 不要 HPS1076 HPS1077 Congenital insensitivity to pain with anhidrosis (CIPA), unknown genetic etiology 先天性無痛無汗症[cell.brc.riken.jp]

  • Erythromelalgia

    Heat intolerance (and aggravation of symptoms with standing or exercise) and relief of symptoms with cooling (and elevation of the affected body part and rest) are hallmarks[accessanesthesiology.mhmedical.com] Tests Available Erythermalgia/Paroxysmal Extreme Pain Disorder/Small Fiber Neuropathy/Congenital Insensitivity to Pain (SCN9A) Hereditary Neuropathy Panel Hereditary Sensory[genedx.com] intolerance, and relief with cooling Course: The prognosis and course vary widely.[drpribut.com]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    Type IV features insensitivity to pain, heat intolerance, and mental deficiency.[connects.catalyst.harvard.edu] For example: HSAN2D (channelopathy-associated congenital insensitivity to pain) : patients have homozygous mutations in the SCN9A gene 4,7.[radiopaedia.org] Keywords: Congenital analgesia, congenital insensitivity to pain with anhidrosis, familial trophoneurosis, hereditary sensory and autonomic neuropathy, hereditary sensory[indianjpain.org]

  • Hereditary Sensory Neuropathy

    She had a history of heat intolerance, reduced sweating and fewer tears while crying.[contempclindent.org] See Congenital Insensitivity to Pain Overview.[ncbi.nlm.nih.gov] Hyperhidrosis, muscular weakness, severe gastrointestinal motility disturbances, and intolerance to moderate heat have also been described in affected individuals.[ncbi.nlm.nih.gov]

  • Neuropathy

    intolerance Excessive sweating or not being able to sweat Bowel, bladder or digestive problems Changes in blood pressure, causing dizziness or lightheadedness Peripheral[mayoclinic.org] Familial dysautonomia (FD)/Riley Day III AR 9q31 IKBKAP Congenital insensitivity to pain with anhidrosis (CIPA) IV AR 1q21-22 NTRK1 (TRKA) Congenital insensitivity to pain[ncbi.nlm.nih.gov] intolerance and altered sweating Bowel, bladder or digestive problems Changes in blood pressure, causing dizziness or lightheadedness Peripheral neuropathy can affect one[mayoclinic.org]

  • Neuropathic Arthropathy

    Both patients have significant axial and appendicular bone abnormalities, Charcot-type arthopathy, heat intolerance and also anhidrosis. They have normal intelligence.[ncbi.nlm.nih.gov] Profile of Ashlyn Blocker, 13, who has congenital insensitivity to pain.[en.wikipedia.org] And this heat intolerance is made worse by the fact that they live in a hot, dry desert climate.[eorthopod.com]

  • Dysautonomia

    While such patients may also experience symptoms including fatigue, sleep disturbances, altered cognitive function (brain fog), cold or heat intolerance, headaches, and bladder[synergyhealthconcepts.com] Absent innervation of skin and sweat glands in congenital insensitivity to pain with anhidrosis. Clin Neurophysiol. 2000 Sep. 111(9):1596-601. [Medline].[emedicine.medscape.com] Many children and adults with mitochondrial disease complain of erratic symptoms that "don't make sense", such as heat intolerance, erratic blood pressure, dizziness, nausea[mitoaction.org]

  • Rapp-Hodgkin Syndrome

    Other common features include sparse, brittle, and dry hair with alopecia in adulthood together with hypohidrosis (a reduced ability to sweat) and heat intolerance, dental[diseaseinfosearch.org] insensitivity to pain with anhidrosis ) KIT ( KIT Piebaldism , Gastrointestinal stromal tumor ) STPK AMHR2 ( Persistent Müllerian duct syndrome II ) TGF beta receptors :[en.wikipedia.org] intolerance, dental anomalies, hearing impairment , high forehead, cone-shaped incisors and enamel hypoplasia (thin or absent tooth enamel), microdontia (decreased width[xpertdox.com]

  • Acute Pandysautonomia

    : Rare; involvement of both sympathetic and parasympathetic nervous systems; somatic fibres not affected; rare; usually have orthostatic hypotension, anhidrosis, cold or heat[podiapaedia.org] J-Pediatr-Orthop. 2001 Mar-Apr; 21(2): 229-32 Lawoyin,-J-O; Lawoyin,-D-O Congenital insensitivity to pain: report of two cases.[malattierare.regione.veneto.it] Skin biopsy is also useful in congenital causes of autonomic neuropathy, as in congenital insensitivity to pain with anhidrosis (CIPA), where a lack of nerve fibers in the[ihpotblogspot.blogspot.com]

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