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486 Possible Causes for Congenital Pain Insensitivity, Hypotension

  • Autonomic Neuropathy

    Abstract Congenital insensitivity (HSAN) to pain is a rare disorder, which affects the body's painprotective mechanism and predisposes the patient to increased risk and incidence[ncbi.nlm.nih.gov] We present a unique case of orthostatic hypotension as the sole feature of a CRMP-5 paraneoplastic autonomic neuropathy in a patient with small cell lung cancer.[ncbi.nlm.nih.gov] 1型遺伝性感覚性自律神経性ニューロパチー 4型遺伝性感覚性自律神経性ニューロパチー Autosomal Dominant Neuropathy Hereditary Sensory Radicular Congenital Insensitivity to Pain with Anhidrosis Congenital Pain Insensitivity[lsd-project.jp]

  • Hereditary Sensory Neuropathy

    See Congenital Insensitivity to Pain Overview.[ncbi.nlm.nih.gov] […] on, the perception of pain and temperature may be either partially or completely absent, followed by depressed reflexes and autonomic dysfunction presenting with postural hypotension[symptoma.com] Hypertension appears to be better tolerated than hypotension.[doi.org]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    For example: HSAN2D (channelopathy-associated congenital insensitivity to pain) : patients have homozygous mutations in the SCN9A gene 4,7.[radiopaedia.org] In the cardiovascular system, postural hypotension, orthostatic hypotension and syncopal episodes are common.[ijaweb.org] Hypertension appears to be better tolerated than hypotension.[ojrd.biomedcentral.com]

  • Channelopathy-Associated Congenital Insensitivity to Pain

    Congenital pain insensitivity is a rare genetic disorder characterized by the inability to perceive pain.[symptoma.com] Our patients repeatedly experienced intraoperative hypotension without bradycardia, probably due to autonomic dysfunction.[link.springer.com] Abstract The congenital pain insensitivity syndrome is accompanied by: a) the presence of a yellow-brown pigment in the basal layer of the epidermis with the histochemical[ncbi.nlm.nih.gov]

  • Aromatic L-Amino Acid Decarboxylase Deficiency

    Absent innervation of skin and sweat glands in congenital insensitivity to pain with anhidrosis. Clin Neurophysiol. 2000 Sep. 111(9):1596-601. [Medline].[emedicine.medscape.com] […] aromatic L-amino acid decarboxylase deficiency who developed serious cardiac rhythm disturbances during treatment with intravenous dopamine and norepinephrine for severe hypotension[ncbi.nlm.nih.gov] […] constriction of the pupils of the eyes (miosis), inappropriate or impaired sweating, nasal congestion, drooling, reduced ability to control body temperature, low blood pressure (hypotension[ghr.nlm.nih.gov]

  • Familial Dysautonomia

    1型遺伝性感覚性自律神経性ニューロパチー 4型遺伝性感覚性自律神経性ニューロパチー Autosomal Dominant Neuropathy Hereditary Sensory Radicular Congenital Insensitivity to Pain with Anhidrosis Congenital Pain Insensitivity[lsd-project.jp] We questioned why despite low blood pressure standing, surprisingly few familial dysautonomia patients complain of symptomatic hypotension or have syncope.[ncbi.nlm.nih.gov] BACKGROUND: In patients with familial dysautonomia (FD), prominent orthostatic hypotension (OH) endangers cerebral perfusion.[ncbi.nlm.nih.gov]

  • Autonomic Nervous System Disorder

    […] onset Widespread anhidrosis, lost sense of pain, mental retardation Loss of myelinated and small unmyelinated fibers Type V Autosomal recessive Congenital onset Pain insensitivity[emedicine.medscape.com] For example, head-up tilt testing (HUT) is only helpful for diagnosing reflex syncope or orthostatic hypotension.[touchneurology.com] It may be an integral component of certain hereditary sensory and autonomic neuropathies, such as congenital insensitivity to pain with anhidrosis (type IV).[jnnp.bmj.com]

  • Acute Pandysautonomia

    J-Pediatr-Orthop. 2001 Mar-Apr; 21(2): 229-32 Lawoyin,-J-O; Lawoyin,-D-O Congenital insensitivity to pain: report of two cases.[malattierare.regione.veneto.it] hypotension were present.[dokumen.tips] Skin biopsy is also useful in congenital causes of autonomic neuropathy, as in congenital insensitivity to pain with anhidrosis (CIPA), where a lack of nerve fibers in the[ihpotblogspot.blogspot.com]

  • Dysautonomia

    Absent innervation of skin and sweat glands in congenital insensitivity to pain with anhidrosis. Clin Neurophysiol. 2000 Sep. 111(9):1596-601. [Medline].[emedicine.medscape.com] […] with postprandial hypotension when oral foods and fluids are withheld perioperatively.[doi.org] HSAN IV (CIPA: congenital insensitivity to pain with anhydrosis) It is a congenital disease with AR inheritance.[tankonyvtar.hu]

  • Roy-Maroteaux-Kremp Syndrome

    […] dystrophy with cataracts and intellectual disability Congenital Pain Insensitivity Congenital Symmetric Circumferential Skin Creases Conn's syndrome Contiguous Abcd1/Dxs1375e[rgd.mcw.edu] Sudden Unexpected Nocturnal Death Syndrome Summitt Syndrome SUNCT Syndrome superior mesenteric artery syndrome Superior Vena Cava Syndrome Supernumerary Der(22)t(8 supine hypotensive[rgd.mcw.edu] Muscular Dystrophy associated with Calf Hypertrophy, Microcephaly, and Severe Mental Retardation Congenital Muscular Dystrophy plus Mental Retardation congenital muscular[rgd.mcw.edu]

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