Create issue ticket

100 Possible Causes for Congenital Pain Insensitivity, Shy Drager Syndrome

  • Autonomic Neuropathy

    Abstract Congenital insensitivity (HSAN) to pain is a rare disorder, which affects the body's painprotective mechanism and predisposes the patient to increased risk and incidence[ncbi.nlm.nih.gov] […] atrophy with autonomic failure (Shy-Drager syndrome) Parkinson’s syndrome with autonomic failure Secondary causes of autonomic neuropathy include: Amyloidosis (abnormal protein[my.clevelandclinic.org] 1型遺伝性感覚性自律神経性ニューロパチー 4型遺伝性感覚性自律神経性ニューロパチー Autosomal Dominant Neuropathy Hereditary Sensory Radicular Congenital Insensitivity to Pain with Anhidrosis Congenital Pain Insensitivity[lsd-project.jp]

  • Familial Dysautonomia

    1型遺伝性感覚性自律神経性ニューロパチー 4型遺伝性感覚性自律神経性ニューロパチー Autosomal Dominant Neuropathy Hereditary Sensory Radicular Congenital Insensitivity to Pain with Anhidrosis Congenital Pain Insensitivity[lsd-project.jp] Dysautonomia may occur as the result of other diseases, such as diabetes mellitus, multiple system atrophy (Shy-Drager syndrome), Guillain-Barré syndrome and a number of other[internationalpain.org] Most people who are diagnosed with Shy-Drager syndrome die within seven to 10 years after symptoms begin.[rarediseasesnetwork.org]

  • Autonomic Nervous System Disorder

    […] onset Widespread anhidrosis, lost sense of pain, mental retardation Loss of myelinated and small unmyelinated fibers Type V Autosomal recessive Congenital onset Pain insensitivity[emedicine.medscape.com] The previous nosologic classification, particularly the use of the term ShyDrager syndrome, was misleading and did not reflect current knowledge about autonomic disorders[nejm.org] It may be an integral component of certain hereditary sensory and autonomic neuropathies, such as congenital insensitivity to pain with anhidrosis (type IV).[jnnp.bmj.com]

  • Channelopathy-Associated Congenital Insensitivity to Pain

    Congenital pain insensitivity is a rare genetic disorder characterized by the inability to perceive pain.[symptoma.com] Pediatr Neurol 1994; 11:50–6Rosemberg, S Marie, SKN Kliemann, S Malan MD, Crago RR: Anaesthetic considerations in idiopathic orthostatic hypotension and the Shy-Drager syndrome[anesthesiology.pubs.asahq.org] Abstract The congenital pain insensitivity syndrome is accompanied by: a) the presence of a yellow-brown pigment in the basal layer of the epidermis with the histochemical[ncbi.nlm.nih.gov]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    For example: HSAN2D (channelopathy-associated congenital insensitivity to pain) : patients have homozygous mutations in the SCN9A gene 4,7.[radiopaedia.org] Pediatr Neurol 1994; 11:50–6Rosemberg, S Marie, SKN Kliemann, S Malan MD, Crago RR: Anaesthetic considerations in idiopathic orthostatic hypotension and the Shy-Drager syndrome[anesthesiology.pubs.asahq.org] Keywords: Congenital analgesia, congenital insensitivity to pain with anhidrosis, familial trophoneurosis, hereditary sensory and autonomic neuropathy, hereditary sensory[indianjpain.org]

  • Dysautonomia

    Absent innervation of skin and sweat glands in congenital insensitivity to pain with anhidrosis. Clin Neurophysiol. 2000 Sep. 111(9):1596-601. [Medline].[emedicine.medscape.com] Anesth Analg 2004; 98:40–5 Hutchinson RC, Sugden JC: Anaesthesia for Shy-Drager syndrome.[doi.org] HSAN IV (CIPA: congenital insensitivity to pain with anhydrosis) It is a congenital disease with AR inheritance.[tankonyvtar.hu]

  • Ondine Syndrome

    1) Congenital insensitivity to pain There have been at least 100 documented cases in the United States of people who report the lack of painful sensations from things like[docshop.com] Shy-Drager Syndrome Support Group Listserver In May 1995, the Vanderbilt Autonomic Dysfunction Center initiated a free Shy-Drager Syndrome electronic mail list so that patients[ww2.mc.vanderbilt.edu] By contrast, those with congenital insensitivity to pain cannot feel such things and can actually suffer significant blood loss because of them. 2) Moebius Syndrome Each year[docshop.com]

  • Acute Pandysautonomia

    J-Pediatr-Orthop. 2001 Mar-Apr; 21(2): 229-32 Lawoyin,-J-O; Lawoyin,-D-O Congenital insensitivity to pain: report of two cases.[malattierare.regione.veneto.it] S.: Holmes-Adie syndrome with segmentai hypohidrosis. Neurology 17:763, 1967. 19. Rosen, J., and Brown, S. I.: New ocular signs in Shy-Drager syndrome. Am. J.[dokumen.tips] Skin biopsy is also useful in congenital causes of autonomic neuropathy, as in congenital insensitivity to pain with anhidrosis (CIPA), where a lack of nerve fibers in the[ihpotblogspot.blogspot.com]

  • Familial Progressive Polyneuropathy

    […] atrophy with autonomic failure (Shy-Drager syndrome) Parkinson’s syndrome with autonomic failure Secondary causes of autonomic neuropathy include: Amyloidosis (abnormal protein[my.clevelandclinic.org] […] onset Widespread anhidrosis, lost sense of pain, mental retardation Loss of myelinated and small unmyelinated fibers Type V Autosomal recessive Congenital onset Pain insensitivity[emedicine.medscape.com] - ウェゲナー肉芽腫症 Wegener’s granulomatosis WG 特発性拡張型心筋症 Idiopathic cardiomyopathy DCM 多系統萎縮症 multiple system atrophy MSA 線条体黒質変性症 striato‐nigral degeneration SND シャイ・ドレーガー症候群 Shy-Drager[nanbyou-soudan.jp]

  • Autosomal Recessive Spastic Paraplegia Type 7

    , see congenital insensitivity to pain asymmetric hypoplasia of facial structures, see craniofacial microsomia ataxia neuropathy spectrum ataxia telangiectasia syndrome, see[mygenomics.com] الصفحة 196 - Glial cytoplasmic inclusions in the CNS of patients with multiple system atrophy (striatonigral degeneration, olivopontocerebellar atrophy and Shy-Drager syndrome[books.google.com] […] chondrodystrophy, see asphyxiating thoracic dystrophy asphyxiating thoracic dysplasia, see asphyxiating thoracic dystrophy asphyxiating thoracic dystrophy asymbolia for pain[mygenomics.com]

Further symptoms