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293 Possible Causes for Congenital Pain Insensitivity, Slow Pulse

  • Autonomic Neuropathy

    In addition to hypotension, many newly recognized syndromes can be attributed to cardiac autonomic neuropathy such as orthostatic tachycardia and bradycardia.[ncbi.nlm.nih.gov] Abstract Congenital insensitivity (HSAN) to pain is a rare disorder, which affects the body's painprotective mechanism and predisposes the patient to increased risk and incidence[ncbi.nlm.nih.gov] […] abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhea, constipation Cardiovascular system: disturbances of heart rate (tachycardia, bradycardia[en.wikipedia.org]

  • Channelopathy-Associated Congenital Insensitivity to Pain

    Our patients repeatedly experienced intraoperative hypotension without bradycardia, probably due to autonomic dysfunction.[link.springer.com] Congenital pain insensitivity is a rare genetic disorder characterized by the inability to perceive pain.[symptoma.com] In one 19-month-old child, severe bradycardia progressed to fatal cardiac arrest.[anesthesiology.pubs.asahq.org]

  • Hereditary Sensory Neuropathy

    However, these patients are prone to perioperative complications such as hyperthermia, hypothermia, and cardiac complications like bradycardia and hypotension.[saudija.org] See Congenital Insensitivity to Pain Overview.[ncbi.nlm.nih.gov] Mistaken identity: Severe vomiting, bradycardia and hypotension after eating a wild herb. Clin Toxicol 50: 532-533, 2012.[higashiomi.hosp.go.jp]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    In one 19-month-old child, severe bradycardia progressed to fatal cardiac arrest.[anesthesiology.pubs.asahq.org] For example: HSAN2D (channelopathy-associated congenital insensitivity to pain) : patients have homozygous mutations in the SCN9A gene 4,7.[radiopaedia.org] Keywords: Congenital analgesia, congenital insensitivity to pain with anhidrosis, familial trophoneurosis, hereditary sensory and autonomic neuropathy, hereditary sensory[indianjpain.org]

  • Autonomic Dysreflexia

    Sweating above level of spinal injury Nausea Slow pulse (less than 60 beats per minute) Cold, clammy skin below level of spinal injury Causes of autonomic dysreflexia Samantha[helpinghandshomecare.co.uk] It may be an integral component of certain hereditary sensory and autonomic neuropathies, such as congenital insensitivity to pain with anhidrosis (type IV).[jnnp.bmj.com] Sweating above level of spinal injury Nausea Slow pulse (less than 60 beats per minute) Cold, clammy skin below level of spinal injury Causes of autonomic dysreflexia Mel[helpinghandshomecare.co.uk]

  • Long QT Syndrome

    Postnatal course was complicated by profound bradycardia, prolonged corrected QT interval (651 ms), 2:1 atrioventricular block, and cardiogenic shock.[ncbi.nlm.nih.gov] Congenital Insensitivity to Pain with Anhidrosis Yasuhiro Indo. Initial Posting: August 5, 2008; Last Update: April 17, 2014.[ncbi.nlm.nih.gov] Isolated sinus bradycardia with a QTc 490ms was found in 35: 33 had a KCNQ1 mutation There was one false positive and one false negative LQTS diagnosis.[ncbi.nlm.nih.gov]

  • Neuropathy

    […] abdominal pain, nausea, vomiting, malabsorption, fecal incontinence, gastroparesis, diarrhoea, constipation Cardiovascular system: disturbances of heart rate (tachycardia, bradycardia[en.wikipedia.org] Familial dysautonomia (FD)/Riley Day III AR 9q31 IKBKAP Congenital insensitivity to pain with anhidrosis (CIPA) IV AR 1q21-22 NTRK1 (TRKA) Congenital insensitivity to pain[ncbi.nlm.nih.gov] Congenital insensitivity to pain with anhidrosis: an NGF/TrkA-ralated disorder.[ncbi.nlm.nih.gov]

  • Thrombocytopenia

    Triplet one had increasing apnoeas and bradycardias, with a metabolic acidosis on day 12.[doi.org] insensitivity to pain with anhidrosis ) KIT ( KIT Piebaldism, Gastrointestinal stromal tumor ) STPK AMHR2 ( Persistent Müllerian duct syndrome II ) TGF beta receptors : Endoglin[en.wikipedia.org] […] intracerebral hemorrhage. [9] However, cordocentesis in the presence of a low platelet count may lead to serious complications, these included slowing of the baby’s heart (fetal bradycardia[en.wikipedia.org]

  • Ondine Syndrome

    Noah has some of the eye issues, swallowing issues, had bradycardia as a baby and temperature control problems.[yourcurseismymiracle.blogspot.com] 1) Congenital insensitivity to pain There have been at least 100 documented cases in the United States of people who report the lack of painful sensations from things like[docshop.com] Case report The delivery of this female baby occurred by caesarian section at 40 WG for fetal bradycardia. Apgar score was 9/9/9. Apneas led to tracheal intubation.[ashg.org]

  • Congenital Malformations of Other Endocrine Glands

    […] bone growth Symptoms in Childhood or Adolescence: Slow growth Delayed tooth development Delayed puberty Puffy and swollen face Hair loss Dry skin Slow pulse Cold intolerance[chw.org] insensitivity to pain with anhidrosis ) KIT ( KIT Piebaldism, Gastrointestinal stromal tumor ) STPK AMHR2 ( Persistent Müllerian duct syndrome II ) TGF beta receptors : Endoglin[en.wikipedia.org] Dry skin Slow pulse Weight gain (modest, no more than 5-10 lbs) The symptoms of hypothyroidism may resemble other conditions or medical problems.[stanfordchildrens.org]

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