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21 Possible Causes for Congestive Heart Failure, Muscle Biopsy showing Presence of Vacuoles

  • Glycogen Storage Disease Type 2

    Congestive heart failure, respiratory failure, and/or aspiration pneumonia are the most frequent causes of death, which usually occurs within 1 year [1].[path.upmc.edu] Muscle biopsy in Pompe disease shows the presence of vacuoles that stain positively for glycogen.[dx.doi.org] Congestive heart failure or cardiomegaly is an important finding and suggests the diagnosis. This may be accompanied by a systolic murmur. Hepatomegaly may be present.[emedicine.medscape.com]

  • Cardiodysrhythmic Potassium-Sensitive Periodic Paralysis

    C 25 SORT: KEY RECOMMENDATIONS FOR PRACTICE Clinical recommendation Evidence rating References Patients with a history of congestive heart failure or myocardial infarction[aafp.org] In periodic paralysis muscle biopsy may show a wide range of abnormalities, vacuoles being more specifically linked to the disease.[ajns.paans.org] It can result in palpitations, syncope, thromboembolic stroke, and congestive heart failure. {ECO:0000269 PubMed:15922306}.[genecards.org]

  • Myositis

    In a small number of people who have polymyositis, congestive heart failure and heart arrhythmias may develop. Lung disease.[mayoclinic.org] In inclusion body myositis, findings on muscle biopsy may show the presence of vacuolated muscle fibers with basophilic granular deposits, the presence of varying degrees[rheumatologyadvisor.com] Heart block,arrhythmias, congestive heart failure, pericarditis, myocardial infarction. Dysphagia, malabsorption. Infection.[patient.info]

  • Focal Myositis

    Heart Failure 422 Case 67 An Elderly Woman with a Progressive Neuropathy 429 Case 68 A Young Woman with Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent[books.google.com] In inclusion body myositis, findings on muscle biopsy may show the presence of vacuolated muscle fibers with basophilic granular deposits, the presence of varying degrees[rheumatologyadvisor.com] Heart block,arrhythmias, congestive heart failure, pericarditis, myocardial infarction. Dysphagia, malabsorption. Infection.[patient.info]

  • Oculopharyngeal Muscular Dystrophy

    Results: Ejection fractions at the time of evaluation were normal in all, and one went on to develop congestive heart failure.[n.neurology.org] Muscle biopsy in the four affected patients showed variation in fiber size, and the presence of small angulated fibers and occasional rimmed vacuoles.[ncbi.nlm.nih.gov] They range from cardiomyopathies, congestive heart failure deformities and pneumonia.[muscleatrophy.net]

  • Distal Myopathy Type 3

    heart failure ( 17 39 40 ).[jnnp.bmj.com] The electromyograhy (EMG) shows a myopatic pattern and the muscles biopsy reveals dystrophic changes without the presence of rimmed vacuoles 1,4.[scielo.br] However, heart failure from DCM is a common cause of death in the mid-40s. DMD-associated DCM is characterized by left ventricular dilation and congestive heart failure.[blueprintgenetics.com]

  • Myopathy, Endocrine

    Heart Failure 422 Case 67 An Elderly Woman with a Progressive Neuropathy 429 Case 68 A Young Woman with Difficulty Swallowing 433 Case 69 A Young Woman with Intermittent[books.google.com] Muscle biopsy shows inflammation of muscle, fibre necrosis and the presence of vacuoles and filamentous inclusions in fibres (seen by electron microscopy).[somalidoc.com] In inclusion body myositis, findings on muscle biopsy may show the presence of vacuolated muscle fibers with basophilic granular deposits, the presence of varying degrees[rheumatologyadvisor.com]

  • Inclusion Body Myositis

    Because of persistent respiratory distress unresponsive to standard therapy for congestive heart failure, chronotropic insufficiency, and pulmonary hypertension, further evaluation[ncbi.nlm.nih.gov] Muscle biopsy will also show rimmed vacuoles (abnormal cellular structures that are also called inclusion bodies), amyloid deposits (presence of abnormal proteins), and endomysial[hss.edu] Muscle Biopsy Findings Biopsied tissue from affected muscles may show inflammation around muscle fibers and small groups of atrophied fibers.[hss.edu]

  • Granulomatous Myositis

    Heart block,arrhythmias, congestive heart failure, pericarditis, myocardial infarction. Dysphagia, malabsorption. Infection.[patient.info] In inclusion body myositis, findings on muscle biopsy may show the presence of vacuolated muscle fibers with basophilic granular deposits, the presence of varying degrees[rheumatologyadvisor.com] The T-cell receptor repertoire observed in lymphocytes that have been isolated from the muscles of these patients shows restriction when compared to the lymphocytes of the[rheumatologyadvisor.com]

  • Proximal Myopathy with Extrapyramidal Signs

    heart failure, heart arrest, ventricular tachycardia, cardiac arrhythmia, sinoatrial node dysfunction, flushing Uncommon (0.1% to 1%): Conduction disturbances Very rare ([drugs.com] Muscle biopsy shows the presence of vacuoles, containing glycogen, in muscle fibers, which are present during an attack, and which may decrease in number immediately after[intranet.tdmu.edu.ua] […] hypotension, and photosensitivity. [ Ref ] Cardiovascular Very common (10% or more): Hypotension (up to 20.2%) Common (1% to 10%): Bradycardia, blood pressure decreased, congestive[drugs.com]

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