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61 Possible Causes for Congophilic Staining, Phagocytic Vacuoles with Degraded Membranous Material

  • Myofibrillar Myopathy Type 3
  • Amyloidosis

    Amyloidosis is characterized by extracellular deposition of abnormal protein. There are six types: primary, secondary, hemodialysis-related, hereditary, senile, and localized. Primary (AL) amyloidosis is associated with monoclonal light chains in serum and/or urine with 15% of patients having multiple myeloma. Secondary[…][ncbi.nlm.nih.gov]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • ADan Amyloidosis

    In particular, they are congophilic (stained with Congo red), they fluorescent following staining with thioflavin S and they are composed of fibrils which are visible under[neurologia.com.pl]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Ampulla of Vater Obstruction Syndrome

    Ampullary biopsy with kappa light chain immunohistochemistry staining revealing infiltration with a congophilic material of apple-green birefringence consistent with amyloid[acgcasereports.gi.org]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Glomerulonephritis

    Three glomeruli (including the two with crescents) showed small segmental mesangial accumulations of Congophilic material that stained immunohistochemically for amyloid A[academic.oup.com]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Multiple Myeloma

    Microscopic examination of the gastric mass revealed amorphous deposits that were congophilic in nature and stained positive with Alcian blue.[ncbi.nlm.nih.gov] Some authors associate weak Congo red staining of the fibrils with delayed disease onset and associate a strong affinity to Congo red with early presentation of the disease[cjasn.asnjournals.org] Of note, in elderly Swedish patients with SSA (WT-TTR), postmortem analysis revealed minimal congophilic material in the renal cortex, although, as previously mentioned, SSA[cjasn.asnjournals.org]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Paraparesis

    Congophilic angiopathy was present. There was mild patchy loss of pigmented neurons of the substantia nigra with no Lewy bodies.[academic.oup.com] Bielschowsky silver stains of the cerebral cortex and hippocampus showed numerous NFTs, and many ‘cotton wool’ and classical neuritic plaques.[academic.oup.com]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Myositis

    The Congo red stain demonstrates congophilic material in vacuolated fibers that is likely to represent amyloid deposition.[ncbi.nlm.nih.gov]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Immunoglobulin Heavy Chain Deficiency

    Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and[…][books.google.de]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material
  • Hereditary Corneal Dystrophy

    These are poorly visualized with routine hematoxylin-eosin staining; however, the lesions are congophilic and revealed as distinct amyloid deposits with Congo red staining[entokey.com]

    Missing: Phagocytic Vacuoles with Degraded Membranous Material

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