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82 Possible Causes for Constipation, Facial Muscle Weakness and Progressive Atrophy, Limb Weakness

  • Lambert Eaton Myasthenic Syndrome

    The Lambert-Eaton myasthenic syndrome (LEMS) is a neuromuscular disease; its unique symptoms of LEMS include dry mouth with a metallic taste, constipation, and erectile dysfunction[ncbi.nlm.nih.gov] MuSK MG should be considered if there is facial or tongue weakness with atrophy, or weakness that predominates in neck or shoulder muscles.[docksci.com] Here, we describe a patient with a 5-year history of cervical myelopathy who presented with recurrent limb weakness of her limbs and complained of recent progressive weakness[ncbi.nlm.nih.gov]

  • Spinal Muscular Atrophy Type 1

    Additional findings include atrophy and fasciculations of the tongue, gastrointestinal problems (gastroesophageal reflux, constipation, and delayed gastric emptying) bulbar[symptoma.com] We present a baby with spinal muscular atrophy type 1, an inherited disorder causing progressive weakness, leading to complete paralysis of respiratory, facial and limb muscles[ncbi.nlm.nih.gov] Symptoms include tremors of the hands, muscle cramps, limb weakness, and twitching.[healthline.com]

  • Spinal Muscular Atrophy

    The most common side effects found in participants in the clinical trials on Spinraza were upper respiratory infection, lower respiratory infection and constipation.[fda.gov] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles.[cedars-sinai.edu]

  • Myotonic Dystrophy

    RESULTS: At baseline, the majority of patients reported trouble swallowing in DM1 (55%; n 499 of 913) and constipation in DM2 (53%; n 96 of 180).[ncbi.nlm.nih.gov] Clinical Presentation: Variable, progressive disability; facial and distal limb muscle weakness with myotonia; cataracts; cardiac conduction defects; diabetes mellitus; and[ajnr.org] Patient-reported perceived changes (worse/stable) in balance, walking, lower-limb weakness, stair-climbing and hand weakness were used as criteria.[ncbi.nlm.nih.gov]

  • Adult Spinal Muscular Atrophy

    The patient also had severe chronic constipation for many years. More recently she had developed unremitting diarrhea.[ncbi.nlm.nih.gov] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info] As the disease progresses patients may notice limb weakness starting in the pelvis or shoulders, or weakness of the facial and tongue muscles.[cedars-sinai.edu]

  • Muscular Dystrophy

    Constipation can be a symptom for anyone who is not mobile. This can be treated with laxatives and a high-fibre diet.[patient.info] Abstract Facioscapulohumeral muscular dystrophy is an autosomal-dominant, slowly progressive myopathy that involves facial, shoulder, and upper arm muscles.[ncbi.nlm.nih.gov] The symptoms of FSH dystrophy may appear during childhood with severe facial and limb weakness or develop slowly and gradually in adulthood with progressive difficulty closing[kennedykrieger.org]

  • Neuromuscular Junction Disorder

    Clinical findings include diffuse weakness, hypotonia, weak cry, poor feeding, constipation, and occasionally respiratory distress. The onset is fairly rapid.[academlib.com] Signs: there is ptosis, facial weakness, atrophy of the sternocieidomastoid muscles, cataracts, and decreased intelligence.[academic.sun.ac.za] Diagnosis  Clinical Features:  Proximal Distal limb weakness  Initial presentation with difficulties to walk.[slideshare.net]

  • Motor Neuron Disease

    Common side effects of amitriptyline include: dry mouth, constipation, sweating, problems passing urine, a slight blurring of vision, and drowsiness.[hse.ie] Symptoms include pharyngeal muscle weakness (involved with swallowing), weak jaw and facial muscles, progressive loss of speech, and tongue muscle atrophy.[web.archive.org] Selective distal upper limb muscle weakness and atrophy with non-significant lower limb weakness during follow-up was the most frequent motor pattern, present in 18 patients[ncbi.nlm.nih.gov]

  • Multifocal Motor Neuropathy

    If the nerves serving the organs are involved, diarrhea or constipation may result, as well as loss of bowel or bladder control.[webmd.com] In the first patient the symptoms were slowly progressive with bulbar muscle impairment, generalized weakness, muscular atrophy with cramps and fasciculations.[moh-it.pure.elsevier.com] The initial high-dose intravenous immunoglobulin treatment significantly improved left upper limb muscle weakness.[ncbi.nlm.nih.gov]

  • Spinal Muscular Atrophy Type 3

    weakness that resembled muscular dystrophy, but the muscle biopsy and EMG indicated neuronal disease.[jkna.org] Constipation is a common problem as is being able to control excessive drooling (secretions), and getting proper nutrition and calories for proper weight gain.[smasupport.com] Spinal muscular atrophy is characterised by slowly progressive muscle weakness and atrophy of the limb muscles associated with motor neurone loss in the spinal cord.[patient.info]

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