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19 Possible Causes for Contractures of the Knees and Ankles, Hyperostosis, Narrowing of Medullary Canal

  • Camurati-Engelmann Syndrome

    However, the skull hyperostosis is progressive, and cranial nerve compression often recurs. Corticosteroids may delay skull hyperostosis and cranial nerve impingement.[ncbi.nlm.nih.gov] Certain bone regions (specifically, the endosteal and periosteal surfaces) become abnormally thickened and hardened, which in turn narrows the medullary canal.[encyclopedia.com] Contractures of the knees and ankles may be present at birth and often improve with age.[nature.com]

  • Melorheostosis

    Melorheostosis Leri’s Disease, Flowing Periosteal Hyperostosis One of a group of sclerosing bone disorders Rare Cause is unknown Produces thickening of the endosteum and periosteum[learningradiology.com] The lesions of the cortex are progressive and may result in narrowing of the medullary canal and stenosis of an adjacent lumen, foramen, or of the spinal canal.[boneandspine.com] Flexion contracture of knee is most common, followed by the ankle, hip, and fingers. Pain typically develops in late adolescence and may be the only complaint.[orthopaedicsone.com]

  • Frontometaphyseal Dysplasia

    This condition is characterized by hyperostosis of the skull and prominence of the supraorbital ridges; long bones have flared metaphyses.[ncbi.nlm.nih.gov] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] […] of the hand over the first two decades resulting in marked limitation of movement at the interphalangeal, metacarpophalangeal joints, wrists, elbows, knees, and ankles);[orpha.net]

  • Craniodiaphyseal Dysplasia

    Imbalance will lead to conditions such as osteoporosis or hyperostosis. Osteoblasts build bone, becoming embedded in bone matrix as mature osteocytes.[ncbi.nlm.nih.gov] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] The long bones show extreme asymmetric hyperostosis and sclerosis of the diaphyses and evidence of a modelling defect in the metaphyses.[ncbi.nlm.nih.gov]

  • Sclerosteosis Type 2

    […] hypertelorism, wide and dense clavicles-ribs, sclerotic calvarium, enlarged and sclerotic mandible, sclerotic vertebral end plates and pedicles, sclerotic pelvic bones, cortical hyperostosis[iofbonehealth.org] […] of medullary canal; erlenmeyer flask defect of the bone; clubfoot (genu varus and valgus deformities); relative muscle weakness, especially in pelvic girdle; atrophic muscle[encyclopedia.com] A generalized skeletal hyperostosis in two siblings caused by a novel mutation in the SOST gene .[cambridge.org]

  • Pyknodysostosis

    X-ray showing acroosteolysis hyperostosis with sparing of medullary cavity and normal bone age.[ncbi.nlm.nih.gov] The other radiographic findings were diffuse osteosclerosis and narrow medullary canal.[jocr.co.in] […] of the hands Limited range of motion (wrists, elbows, knees, ankles) Melnick-Needles syndrome Proptosis, full cheeks, micrognathia, facial asymmetry Hypoplasia Long digits[ncbi.nlm.nih.gov]

  • Osteopetrosis

    Osteopetrosis is a rare disorder of osteoclastic bone resorption leading to hyperostosis.[ncbi.nlm.nih.gov] medullary canals.[dx.doi.org] Nine months postoperatively, satisfactory callus formation was noted; however, the prolonged immobilization resulted in contractures of the left hip, knee, and ankle.[healio.com]

  • Pyle's Disease

    Clinical description Cranial involvement is minimal with mild hyperostosis of the skull base, and thickening of the frontal and occipital bones reported in some cases.[orpha.net] Initially begins in the diaphyses and it extends to the metaphyses, sparing the epiphyses. 16,20,21 As a consequence it can be seen a narrowing of the medullary canal with[elsevier.es] […] of the elbows ; - lower extremities - more significantly involved than upper extremities; - varus deformities of the knees and ankles are prestent, with bowing visible in[wheelessonline.com]

  • Spondyloenchondrodysplasia

    Ossification of the spinal ligaments has a specific site of predilection and often occurs in combination with senile ankylosing vertebral hyperostosis.[gooa.las.ac.cn] In cystic form the cortices are continuous and thickened in the concave side of the bow, medullary canal is narrow and an image of a cyst can be seen at the apex of the curvature[boneandspine.com] Kyphosis at the thoracolumbar junction , increased lumbar lordosis Ligament laxity in knee and ankle Genu varum and internal tibial torsion The joints and its cartilage are[authorstream.com]

  • Autosomal Recessive Nail Dysplasia

    Endosteal hyperostosis disorders include Van Buchem disease (types I and II) and sclerosteosis. The two endosteal hyperostosis conditions include many similar features.[encyclopedia.com] , sclerotic medullary canal Type III: Anterior bowig with a cystic lesion or prefracture Type IV: Anterior bowing with a frank fracture and pseudarthrosis usually involving[flinders.edu.au] […] hypertelorism, wide and dense clavicles-ribs, sclerotic calvarium, enlarged and sclerotic mandible, sclerotic vertebral end plates and pedicles, sclerotic pelvic bones, cortical hyperostosis[iofbonehealth.org]

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