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91 Possible Causes for Coombs Negative Hemolytic Anemia

  • Nonimmune Hemolysis

    Coomb's negative autoimmune hemolytic anemia: A diagnostic dilemma for the hematologist.[] Abstract Non-immune hemolytic anemia (NIHA) is characterized by positive routine hemolytic tests but negative anti-human immunoglobulin (Coombs) test.[] […] aplasia following delivery due to Coombs-negative autoimmune hemolytic anemia and hemophagocytosis.[]

  • Microangiopathic Hemolytic Anemia

    The patients presented with an acute onset of Coombs negative hemolytic anemia and fragmentocytes in the peripheral blood smear which are typical for MAHA.[] Cancer-related microangiopathic hemolytic anemia (CR-MAHA) is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia[] anemia (CR-MAHA) is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia.[]

  • Hemolytic Uremic Syndrome

    BACKGROUND: Hemolytic uremic syndrome is characterized by acute renal failure, thrombocytopenia, and Coombs-negative hemolytic anemia.[] Hemolytic uremic syndrome (HUS) is a clinical triad of Coombs-negative microangiopathic hemolytic anemia, thrombocytopenia, and acute renal failure ( 1 ).[] Blood chemistry showed Coombs-negative hemolytic anemia (hemoglobin level 5.5 g/dl) with red blood cell fragmentation and thrombocytopenia (72 10 3 /μl).[]

  • Sickle Cell Disease

    Sickle cell disease (SCD) usually manifests early in childhood. For the first 6 months of life, infants are protected largely by elevated levels of Hb F; soon thereafter, the condition becomes evident. The most common clinical manifestation of SCD is vaso-occlusive crisis. A vaso-occlusive crisis occurs when the[…][]

  • Blackwater Fever

    Am J Trop Med Hyg. 2017 Dec;97(6):1804-1807. doi: 10.4269/ajtmh.17-0533. Epub 2017 Sep 28. Author information 1 University of Queensland, School of Public Health, Brisbane, Australia. 2 Australian Army Malaria Institute, Enoggera, Australia. Abstract Blackwater fever is a massive hemolytic event usually occurring in the[…][]

  • Malaria

    INTRODUCTION: Here, we conducted an epidemiological study of hepatitis B virus (HBV) mono-infected and asymptomatic malaria/HBV coinfected immigrants and further discussed the possibility of malaria disease modifying the clinical presentation of HBV infection. METHODS: A total of 195 African immigrants were examined[…][]

  • Erythrocyte Membrane Abnormality

    Abstract The protein composition of ghosts, inside-out vesicles (IOV), and membrane skeletons (MS) of erythrocytes (RBC) from splenectomized (spx) and nonsplenectomized (non-spx) patients with beta-thalassemia major and beta-thalassemia intermedia was determined. Ghosts from spx thalassemia intermedia patients[…][]

  • Glycogen Storage Disease Type 1

    Abstract We report molecular and clinical findings in 13 patients with rare types of glycogen storage disease 1 (GSD1 non-a). Analysis of G6PT encoding a microsomal transporter protein has revealed mutations on both chromosomes in each case, four of which are novel. Diagnosis has been confirmed in three patients[…][]

  • Weil's Disease

    Abstract The case of a patient with leptospirosis (treated with trimethoprim) with late neurological complications manifesting as a bilateral plexus syndrome is described. The probable reasons for the continued weakness, in this patient, of the muscles supplied by the anterior interosseus nerve, despite improvement[…][]

  • Bartonella Infection

    Abstract Bartonella infection can be difficult to diagnose, especially when it manifests as bacteremia, which is usually accompanied by nonspecific symptoms, such as fever. Therefore, we hypothesized that Bartonella infection represents an underrecognized cause of febrile illness. To determine the prevalence of[…][]

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