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130 Possible Causes for Coombs Negative Hemolytic Anemia

  • Microangiopathic Hemolytic Anemia

    The patients presented with an acute onset of Coombs negative hemolytic anemia and fragmentocytes in the peripheral blood smear which are typical for MAHA.[] Cancer-related microangiopathic hemolytic anemia (CR-MAHA) is a paraneoplastic syndrome characterized by Coombs-negative hemolytic anemia with schistocytes and thrombocytopenia[] Cut-off value of red-blood-cell-bound IgG for the diagnosis of Coombs-negative autoimmune hemolytic anemia. Am J Hematol . 2009 Feb. 84(2):98-101. [Medline] .[]

  • Hemolytic Uremic Syndrome

    Hemolytic uremic syndrome is characterized by acute renal failure, thrombocytopenia, and Coombs-negative hemolytic anemia.[] […] smear thrombocytopenia serum creatinine Normal PT/PTT Negative Coombs test bleeding time Differential Characteristics DIC ITP TTP HUS Fever No No Yes Yes/No Splenomegaly No[] ) jaundice (hemolysis) petechiae/purpura uncommon hepatosplenomegaly Evaluation Criteria for HUS hemolytic anemia hematocrit 30% schistocytes (helmet cells) on peripheral[]

  • Nonimmune Hemolysis

    Coomb's negative autoimmune hemolytic anemia: A diagnostic dilemma for the hematologist.[] Abstract Non-immune hemolytic anemia (NIHA) is characterized by positive routine hemolytic tests but negative anti-human immunoglobulin (Coombs) test.[] Non-immune mediated hemolytic anemia (direct Coombs test is negative) Drugs (i.e., some drugs and other ingested substances lead to hemolysis by direct action on RBCs, e.g[]

  • Erythrocyte Membrane Abnormality

    Deficiency of protein 4.2 in erythrocytes from a patient with a Coombs negative hemolytic anemia: evidence for a role of protein 4.2 in stabilizing ankyrin on the membrane[]

  • Blackwater Fever

    Cut-off value of red-blood-cell-bound IgG for the diagnosis of Coombs-negative autoimmune hemolytic anemia. Am J Hematol . 2009 Feb. 84(2):98-101. [Medline] .[]

  • Trichuriasis

    hemolytic anemia and macroscopic hematuria. ( 11995911 ) Huicho L. 1995 30 Case in point.[] Ascariasis, trichuriasis, and growth of schoolchildren in Northeastern Peninsular Malaysia. ( 10772554 ) Raj S.M....Naing N.N. 1998 29 Trichuriasis associated to severe transient Coomb's-negative[]

  • Acquired Spherocytosis

    -Immunosuppression Coomb's Negative Hemolytic Anemia (4 Types) -Infection -Paroxysmal Nocturnal Hemoglobinuria (PNH) -Severe Liver Disease -Hypophosphatemia Microorganisms[] HS is the leading cause of direct antiglobulin test (direct Coombs) negative hemolytic anemia requiring erythrocyte transfusion in the first months of life.[] […] cells coated with drug Diseases Associated with Warm Autoimmune Antibodies Treatment for Autoimmune Hemolytic Anemia -Folic Acid -Prednisone -Splenectomy -IVIG -Rituximab[]

  • Metabolic Liver Disease

    hemolytic anemia, renal tubular acidosis, arthritis, and osteopenia. -- To view the remaining sections of this topic, please sign in or purchase a subscription -- TY - ELEC[] Extrahepatic manifestations include Kayser-Fleischer rings in the Descemet membrane in the periphery of the cornea due to copper deposition (diagnosed on slit-lamp examination), Coombs-negative[]

  • Bartonella Infection

    Lobular capillary hemangioma and bacillary angiomatosis due to Bartonella infection share several clinical and histopathologic characteristics. We sought to determine whether lobular capillary hemangioma is caused by the same agent as bacillary angiomatosis. Forty-five pathology specimens with a histologic diagnosis of[…][]

  • Late Congenital Syphilis

    hemolytic anemia Late congenital syphilis Late CS occurs in children who are 2 years of age or older.[] hemolytic anemia (58%), fever (42%), thrombocytopenia (40%), evidence of neurosyphilis (23%), pneumonitis (17%), renal involvement (proteinuria, hematuria; 16%), rhinitis[] Laboratory The following symptoms are observed in the laboratory: Leukopenia Leukocytosis CSF pleocytosis Thrombocytopenia CSF increased protein Increased liver enzymes Coombs-negative[]

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