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705 Possible Causes for Cor Pulmonale, Hypoxia

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  • Chronic Obstructive Pulmonary Disease

    Presence of chronic hypoxia or cor pulmonale.[patient.info] Edema in cor pulmonale. Lancet 1975 ; ii: 1289 – 1290. Google Scholar 27 Richens JM Howard P. Oedema in cor pulmonale. Clin Sci 1982 ; 62: 255 – 259.[doi.org] Because of low cardiac output, however, the rest of the body suffers from tissue hypoxia and pulmonary cachexia.[emedicine.com]

  • Sleep Apnea

    We here report the case of a 36-year-old man with severe OSAS who experienced the recurrence of stroke due to nocturnal hypoxia and a nocturnal BP surge measured by this trigger[ncbi.nlm.nih.gov] Vol 8, No 3 (Autumn 2009) Introduction Cor pulmonale has a well-described association with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD[phaonlineuniv.org] Furthermore, PPAR-α is also reduced by hypoxia.[doi.org]

  • Morbid Obesity

    The risk of postoperative hypoxia is increased by preoperative hypoxia and by any surgery involving the thorax or abdomen.[openanesthesia.org] Arterial oxygen tension is lower and chronic hypoxemia may lead to pulmonary hypertension and cor pulmonale.[openanesthesia.org] These may lead to systemic and pulmonary hypertension and later cor pulmonale and right ventricular failure.[academic.oup.com]

  • Cor Pulmonale

    The first cause of increased PVR is chronic long-standing alveolar hypoxia which induces pulmonary vascular remodeling.[ncbi.nlm.nih.gov] […] lung diseases. [7] Cor Pulmonale Presentation The clinical manifestations of cor pulmonale may be nonspecific.[emedicine.medscape.com] Two distinct mechanisms of action of alveolar hypoxia must be considered: acute hypoxia causes pulmonary vasoconstriction, and chronic longstanding hypoxia induces structural[doi.org]

  • Pulmonary Hypertension

    […] hypertension on chronic exposure to hypoxia.[doi.org] cor pulmonale I26.90 Septic pulmonary embolism without acute cor pulmonale I26.92 Saddle embolus of pulmonary artery without acute cor pulmonale I26.99 Other pulmonary embolism[icd10data.com] […] diagnosis Hypoxia/etiology* Hypoxia/therapy Lung Neoplasms/complications Lung Neoplasms/diagnosis* Lung Neoplasms/therapy Magnetic Resonance Imaging, Cine Middle Aged Neurofibromatosis[ncbi.nlm.nih.gov]

  • Obstructive Sleep Apnea

    Hypoxia damages multiple organ systems especially those with high oxygen utilization such as the central nervous system.[ncbi.nlm.nih.gov] References: [14] [15] Complications Hypertension Hypoxia -induced cardiac arrhythmia Pulmonary hypertension and cor pulmonale Global respiratory insufficiency Cardiac infarction[amboss.com] CONCLUSIONS: The HBI considers both hypoxia duration and severity during sleep.[ncbi.nlm.nih.gov]

  • Pulmonary Fibrosis

    VEGF-A receptors and co-receptors were differentially expressed by hypoxia and hyperoxia.[ncbi.nlm.nih.gov] Cor pulmonale develops in association with end-stage disease and classic signs of right heart failure may be present.[orpha.net] In severe disease, there may be cyanosis eventually leading to respiratory failure, pulmonary hypertension and cor pulmonale.[symptoma.com]

  • Extrapulmonary Alveolar Hypoventilation

    Favorite Patients with unexplained hypoxia. Patients with hypoxia exceeding the degree of their clinical illness.[mdcalc.com] Mixed cardiac and pulmonary disorders are also common sources of dyspnea 6, 7 and include COPD with pulmonary hypertension and cor pulmonale, deconditioning, pulmonary emboli[aafp.org] […] dysfunction – increase cytosolic NADH – block gluconeogenesis and fatty acid oxidation – shunt pyruvate to lactate – cause fatty liver and lactic acidosis # Definition – Hypoxia[usmle287.wordpress.com]

  • Kyphoscoliosis

    V/Q mismatch leads to significant hypoxia, and can progress to symptoms of Cor pulmonale. CXR shows significant distortion of spine and thorax.[meddean.luc.edu] We present the case of a 59-year-old man with congenital kyphoscoliosis who developed cor pulmonale for the first time following intercontinental air travel.[ncbi.nlm.nih.gov] Lilius also described associated malformations in 21.8% of cleft lip/palate children. [6] Hypoxia, hypercapnia, acidosis and any increase in pulmonary vascular resistance[joacp.org]

  • Interstitial Lung Disease

    Worsening hypoxia and respiratory failure may develop with disease progression.[ncbi.nlm.nih.gov] pulmonale).[symptoma.com] Interstitial lung disease (ILD) is characterised by reduced functional capacity, dyspnoea and exercise-induced hypoxia.[ncbi.nlm.nih.gov]

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