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705 Possible Causes for Cor Pulmonale, Hypoxia

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  • Chronic Obstructive Pulmonary Disease

    Presence of chronic hypoxia or cor pulmonale.[] Edema in cor pulmonale. Lancet 1975 ; ii: 1289 – 1290. Google Scholar 27 Richens JM Howard P. Oedema in cor pulmonale. Clin Sci 1982 ; 62: 255 – 259.[] Because of low cardiac output, however, the rest of the body suffers from tissue hypoxia and pulmonary cachexia.[]

  • Sleep Apnea

    We here report the case of a 36-year-old man with severe OSAS who experienced the recurrence of stroke due to nocturnal hypoxia and a nocturnal BP surge measured by this trigger[] Vol 8, No 3 (Autumn 2009) Introduction Cor pulmonale has a well-described association with chronic respiratory diseases such as chronic obstructive pulmonary disease (COPD[] Furthermore, PPAR-α is also reduced by hypoxia.[]

  • Morbid Obesity

    The risk of postoperative hypoxia is increased by preoperative hypoxia and by any surgery involving the thorax or abdomen.[] Arterial oxygen tension is lower and chronic hypoxemia may lead to pulmonary hypertension and cor pulmonale.[] These may lead to systemic and pulmonary hypertension and later cor pulmonale and right ventricular failure.[]

  • Cor Pulmonale

    The first cause of increased PVR is chronic long-standing alveolar hypoxia which induces pulmonary vascular remodeling.[] […] lung diseases. [7] Cor Pulmonale Presentation The clinical manifestations of cor pulmonale may be nonspecific.[] Two distinct mechanisms of action of alveolar hypoxia must be considered: acute hypoxia causes pulmonary vasoconstriction, and chronic longstanding hypoxia induces structural[]

  • Pulmonary Hypertension

    […] hypertension on chronic exposure to hypoxia.[] cor pulmonale I26.90 Septic pulmonary embolism without acute cor pulmonale I26.92 Saddle embolus of pulmonary artery without acute cor pulmonale I26.99 Other pulmonary embolism[] […] diagnosis Hypoxia/etiology* Hypoxia/therapy Lung Neoplasms/complications Lung Neoplasms/diagnosis* Lung Neoplasms/therapy Magnetic Resonance Imaging, Cine Middle Aged Neurofibromatosis[]

  • Obstructive Sleep Apnea

    Hypoxia damages multiple organ systems especially those with high oxygen utilization such as the central nervous system.[] References: [14] [15] Complications Hypertension Hypoxia -induced cardiac arrhythmia Pulmonary hypertension and cor pulmonale Global respiratory insufficiency Cardiac infarction[] CONCLUSIONS: The HBI considers both hypoxia duration and severity during sleep.[]

  • Pulmonary Fibrosis

    VEGF-A receptors and co-receptors were differentially expressed by hypoxia and hyperoxia.[] Cor pulmonale develops in association with end-stage disease and classic signs of right heart failure may be present.[] In severe disease, there may be cyanosis eventually leading to respiratory failure, pulmonary hypertension and cor pulmonale.[]

  • Extrapulmonary Alveolar Hypoventilation

    Favorite Patients with unexplained hypoxia. Patients with hypoxia exceeding the degree of their clinical illness.[] Mixed cardiac and pulmonary disorders are also common sources of dyspnea 6, 7 and include COPD with pulmonary hypertension and cor pulmonale, deconditioning, pulmonary emboli[] […] dysfunction – increase cytosolic NADH – block gluconeogenesis and fatty acid oxidation – shunt pyruvate to lactate – cause fatty liver and lactic acidosis # Definition – Hypoxia[]

  • Kyphoscoliosis

    V/Q mismatch leads to significant hypoxia, and can progress to symptoms of Cor pulmonale. CXR shows significant distortion of spine and thorax.[] We present the case of a 59-year-old man with congenital kyphoscoliosis who developed cor pulmonale for the first time following intercontinental air travel.[] Lilius also described associated malformations in 21.8% of cleft lip/palate children. [6] Hypoxia, hypercapnia, acidosis and any increase in pulmonary vascular resistance[]

  • Interstitial Lung Disease

    Worsening hypoxia and respiratory failure may develop with disease progression.[] pulmonale).[] Interstitial lung disease (ILD) is characterised by reduced functional capacity, dyspnoea and exercise-induced hypoxia.[]

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