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36 Possible Causes for Corneal Infiltrate, Plasmodium

  • Acanthamoeba Keratitis

    It typically presents as a unilateral central or paracentral corneal infiltrate, often with a ring-shaped peripheral infiltrate.[] The progressive nature of the corneal infiltrate, the epithelial defect, and the lack of response to treatment was highly suggestive for Acanthamoeba keratitis.[] The infection is associated with minimal corneal trauma and soft contact lens wear.[]

  • Keratitis

    Pediculosis, Pthiriasis) Liver Flukes (Clonorchiasis, Opisthorchiasis, Fascioliasis) Loiasis ( Loa loa Infection) Lymphatic filariasis (Filariasis, Elephantiasis) Malaria ( Plasmodium[] Adenoviral conjunctivitis may lead to subepithelial corneal infiltrates as a late complication.[] He had undergone a corneal tear repair on that eye 15 days prior to the onset of keratitis. The infiltrations were along the sutured corneal tear tracts.[]

  • Amebiasis

    Therefore, Entamoeba histolytica is second only to the Plasmodium parasite (responsible for malaria) as a protozoan cause of death.[] However, the cornea continued to worsen with 25% corneal thinning inferior to the ring infiltrate.[] A plasmodium-encoded cytokine suppresses T-cell immunity during malaria. Proc Natl Acad Sci U S A. 2012;109(31):E2117–26. . CrossRef Google Scholar 28.[]

  • Pseudomonas Aeruginosa

    Olga Blank, Elisabeth Davioud-Charvet and Mourad Elhabiri, Interactions of the Antimalarial Drug Methylene Blue with Methemoglobin and Heme Targets in Plasmodium falciparum[] The corneal scrape was not performed initially because of the deep infiltrate in the stroma. The patient was examined by in vivo confocal microscopy.[] Novel Plasmodium falciparum metabolic network reconstruction identifies shifts associated with clinical antimalarial resistance.[]

  • Microsporidiosis

    A full scale genome mapping project is needed to allow comparison with the better characterised related parasites Toxoplasma and Plasmodium .[] The corneal infiltrates’ appearance was essentially unchanged.[] FOLLOW UP AT 1 WEEK • Symptomatic improvement • Decreased conjunctival congestion • Reduced corneal epithelial and subepithelial infiltrates 24. 10X 25. • 20 years • Female[]

  • Anterior Uveitis

    22) CMV (n 5) Chlamydia trachomatis (n 10) Filaria (n 2) Aspergillus fumigatus (n 2) Other (n 2) Treponema pallidum (n 9) Giarda lamblia (n 2) Borrelia Burgdorferi (n 7) Plasmodium[] Slit lamp examination revealed multiple disc-shaped corneal stromal infiltrates with an overlying epithelial defect and hypopyon in both the eyes.[] VZV-associated keratitis is interstitial with corneal ring infiltrates and rough dendrites lacking terminal bulbs that can have an elevated appearance. 29 Jap A, Chee SP.[]

  • Corneal Opacity

    Pullan RL, Bukirwa H, Staedke SG, Snow RW, Brooker S (2010) Plasmodium infection and its risk factors in eastern Uganda.[] To rule out corneal infiltration from systemic disease in cases that do not appear typical of hereditary dystrophy, serum chemistry panels, levels of cholesterol and triglycerides[] Acute bilateral corneal opacity is rare but may occur in children with bacterial blepharokeratoconjunctivitis.[]

  • Tuberculosis

    The diagnosis of a severe Plasmodium vivax patient co-infected with HIV and tuberculosis is discussed with an overview of the rapid response mounted by the Anti Malaria Campaign[] Slit lamp examination revealed multiple disc-shaped corneal stromal infiltrates with an overlying epithelial defect and hypopyon in both the eyes.[] Boundenga Larson, Origin of Two Most Virulent Agents of Human Malaria: Plasmodium falciparum and Plasmodium vivax, Malaria [Working Title], 10.5772/intechopen.84481, (2019[]

  • Herpes Simplex Infection

    Protection against Plasmodium falciparum malaria in chimpanzees by immunization with the conserved pre-erythrocytic liver-stage antigen 3.[] CXCL1/KC and CXCL5/LIX are selectively produced by corneal fibroblasts and mediate neutrophil infiltration to the corneal stroma in LPS keratitis.[] Long-term multiepitopic cytotoxic-T-lymphocyte responses induced in chimpanzees by combinations of Plasmodium falciparum liver-stage peptides and lipopeptides.[]

  • Hepatitis B

    HBV infection was diagnosed using serological tests and confirmed by PCR; furthermore, we performed a pan-Plasmodium-specific-nucleic-acid-sequence-based-amplification (NASBA[] Slit-lamp examination revealed severe superior corneal thinning without infiltrate. Corneal ulceration worsened until 10% of the cornea remained.[] RESULTS: PCR-NASBA results confirmed that 62 of 195 subjects (31.8%) were positive for Plasmodium infection, whereas 41 of 195 subjects (21%) tested positive for HBV chronic[]

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