Possible Causes for corneal irritation Sjögren Syndrome • Sore or split skin • Itchy, dry eyes • Corneal ulcerations • Eye infections • Swollen salivary glands • Difficulty swallowing Dangers of Sjogren’s Syndrome Sjogren’s Syndrome [oramd.com] These methods aim to address the discomfort caused by xerostomia, but also to avoid chronic irritation and damage to corneal surface. [rheumatologyadvisor.com] […] surface to evaluate ocular surface irritation Patient history of opthalmic symptoms Testing for oral involvement Salivary sialometry: low salivary flow is defined as less [onlinelibrary.wiley.com] General Anesthesia We report the successful management of general anesthesia for a patient with Pelizaeus-Merzbacher disease (PMD). PMD is one of a group of progressive, degenerative disorders of the cerebral white matter. The typical clinical manifestations of PMD include psychomotor retardation, nystagmus, abnormal muscle tone,[…] [ncbi.nlm.nih.gov] Brandt Syndrome hyposmia, and hypogeusia, and eye abnormalities including conjunctivitis, blepharitis, corneal opacities, and photophobia. [statpearls.com] The systemic features include diarrhea, irritability, lethargy, anorexia, growth retardation, anemia, amenorrhea, neuropsychiatric problems, perinatal morbidity, hypogonadism [statpearls.com] Stevens-Johnson Syndrome […] and dry eyes, or in severe cases may result in corneal ulceration, uveitis (inflammation of the uvea, which is the middle layer of the eye) and possibly blindness Problems [nhs.uk] Chronic irritations and insufficiency of limbal stem cells may lead to metaplasia of the corneal epithelium with ulceration and visus loss, sometimes resulting in blindness [doi.org] and the oesophagus may also become narrowed and scarred (oesophageal stricture) eye problems – the rash can cause problems with your eyes which, in mild cases, may be irritation [nhs.uk] Exposure Keratitis It can be invaded by vessels leading to irritation and decreased corneal transpaency. [en.wikibooks.org] Treatment may require the removal of the loosely attached filaments in the office or a bandage contact lens to protect the irritated corneal surface. [coopereyecare.com] The facial nerve also helps the eye produce tears, so the eye can become even more dry and irritated from poor natural tear production in addition to corneal exposure. [eyeporter.com] Entropion Corneal irritation from the eyelashes rubbing against the eye may cause further irritation and inflammation worsening the problem. [klapperplasticsurgery.com] Symptoms of Ectropion Include: Excessive tearing Crusting of the eyelid Mucus discharge Infection Corneal irritation Sagging skin around the eye Impaired vision Redness and [phillipseye.com] Surgical tape or the sticky part of a Band-Aid, placed from the lower eyelid to the cheek area, will evert the lid and relieve corneal irritation from the eyelashes. [klapperplasticsurgery.com] Secondary Entropion Symptoms of Ectropion Include: Excessive tearing Crusting of the eyelid Mucus discharge Infection Corneal irritation Sagging skin around the eye Impaired vision Redness and [phillipseye.com] irritation Impaired vision Redness and pain of the eye Sensitivity to light and wind Poor drainage of tears Treatment: Artificial tears and lubricating ointments can be used [berkseye.com] […] aging changes Infection Scarring on the inner surface of the eyelid Eyelid injuries Tumors Symptoms of Entropion: Excessive tearing Crusting of the eyelid Mucus discharge Corneal [readocs.com] Cogan Syndrome Cerebellum. 2013 Aug;12(4):557-67. doi: 10.1007/s12311-013-0463-1. Author information 1 INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, ImpAct Team, Bron, 69676, France. muriel.panouilleres@inserm.fr Abstract Ataxia with oculomotor apraxia type 2 (AOA2) is one of the most frequent autosomal recessive[…] [ncbi.nlm.nih.gov] Ectropion Symptoms of Ectropion Include: Excessive tearing Crusting of the eyelid Mucus discharge Infection Corneal irritation Sagging skin around the eye Impaired vision Redness and [phillipseye.com] […] aging changes Infection Scarring on the inner surface of the eyelid Eyelid injuries Tumors Symptoms of Entropion: Excessive tearing Crusting of the eyelid Mucus discharge Corneal [readocs.com] Symptoms of Entropion Excessive tearing Crusting of the eyelid Mucus discharge Corneal irritation Sagging skin around the eye Impaired vision Redness and pain of the eye Sensitivity [phillipseye.com] Vitamin A Deficiency Vitamin A deficiency (VAD) or hypovitaminosis A is a lack of vitamin A in blood and tissues. It is common in poorer countries, but rarely is seen in more developed countries. Nyctalopia (night blindness) is one of the first signs of VAD. Xerophthalmia, keratomalacia, and complete blindness can also occur since vitamin A[…] [en.wikipedia.org] Avitaminosis A ORIGINAL Reduction of vitamin A deficiency and anemia in pregnancy after implementing proposed prenatal nutritional assistance Reducción de avitaminosis A y anemia en el embarazo después de la implementación propuesta de asistencia nutricional prenatal C. Barbosa Chagas 1,2, A. Ramalho 1,2, P. de Carvalho Padilha 1,2, B.[…] [scielo.isciii.es] Lymphedema Distichiasis Syndrome Distichiasis is usually present at birth and can cause corneal irritation or recurrent conjunctivitis 5 in up to 75% of patients; however, it was asymptomatic in this patient [cmaj.ca] Most affected individuals have ocular findings including corneal irritation, recurrent conjunctivitis, and photophobia. [malacards.org] Other ophthalmologic findings may include photophobia, corneal irritation, and partial ectropion of lateral third of eyelashes. [jemds.com] Riboflavin Deficiency Abstract 83 healthy infants in Madang were screened for haematological variables and riboflavin status. 70 (84%) had evidence of riboflavin deficiency. It is suggested that pregnant and lactating women in this area may be deficient, and that riboflavin deficiency may protect infants against malaria. [ncbi.nlm.nih.gov] Congenital Entropion Symptoms primarily arise from irritation of the ocular surface. Corneal abrasions and scarring can occur. [ncbi.nlm.nih.gov] This results in symptomatic contact of the eyelashes with the surface of the globe, resulting in corneal irritation. [ncbi.nlm.nih.gov] Hordeolum Internum This is a cosmetic deformity that can lead to corneal irritation. Chalazion requires surgical removal to avoid further complications. [buzzle.com] Complications The most frequent complication of hordeolum is progression to a chalazion that causes cosmetic deformity, corneal irritation, or the need for surgical removal [emedicine.medscape.com] Rosacea photophobia Often undiagnosed Blepharitis, conjunctivitis, eyelid irregularities, inflammation Corneal complications may decrease visual acuity; vision loss possible View [aafp.org] […] of sties, and corneal damage. [riversol.com] photophobia Often undiagnosed Blepharitis, conjunctivitis, eyelid irregularities, inflammation Corneal complications may decrease visual acuity; vision loss possible Table [aafp.org] Corneal Opacity The BCOP (Bovine Corneal Opacity and Permeability) assay is an in vitro eye irritation test method developed by Gautheron et al. (1992), which uses living bovine corneal tissue [iivs.org] The OECD Test Guideline 437 Bovine Corneal Opacity and Permeability (BCOP) test method allows determining severely irritating substances without animals, and the recently [ncbi.nlm.nih.gov] Abstract The bovine corneal opacity and permeability (BCOP) assay can be used to predict relative eye irritation potential of surfactant-based personal care formulations relative [ncbi.nlm.nih.gov] Acne Vulgaris For a long time I used squalane, but that was no longer sufficient, and everything else seemed to cause irritation. [amazon.com] Hydrocortisone worked, but I knew I wasn't supposed to use it around my face and eyes for too long or it could cause skin thinning and corneal damage. [amazon.com] Blepharitis We have observed seven patients with longstanding complaints of ocular irritation who had blepharitis and/or meibomitis associated with corneal involvement. [ncbi.nlm.nih.gov] Another possible cause is called “recurrent corneal erosion.” Think about pulling a scab off all the time. It starts to heal and you pull the scab off. [info.sjogrens.org] […] ulcer or irritation.[4][9][10] The lids may become red and may have ulcerate, non-healing areas that may lead to bleeding.[8] Blepharitis can also cause blurred vision due [en.wikipedia.org] Keratitis irritation and injury. [visionweb.com] In the advanced stages of this condition, haze and small blisters on the corneal surface may appear, causing pain and irritation. [my.clevelandclinic.org] […] reaction to antibiotics medications, or rheumatic diseases such as rheumatoid arthritis and Sjögren’s Syndrome, in which eye dryness can lead to a greater susceptability toward corneal [visionweb.com] Neuropathy Polymodal receptors are also believed to play a role in reflexive tearing subsequent to irritation of the corneal surface [ 24, 25 ]. [doi.org] There are appropriate responses to pleural effusions, esophageal irritation, and menstrual cramping. [ncbi.nlm.nih.gov] Likewise is the seemly paradoxical finding of decreased corneal sensation with findings of increased pain and irritation (e.g., as seen in diabetic and other neuropathies) [doi.org] Peripheral Neuropathy Polymodal receptors are also believed to play a role in reflexive tearing subsequent to irritation of the corneal surface [ 24, 25 ]. [doi.org] Likewise is the seemly paradoxical finding of decreased corneal sensation with findings of increased pain and irritation (e.g., as seen in diabetic and other neuropathies) [doi.org] Correlation of tear fluorescein clearance and Schirmer test scores with ocular irritation symptoms. [doi.org] Chalazion If left untreated it can result in scarring, corneal ulcer and infection may develop. [murdocheye.com.au] Drainage from the gland may cause irritation of the conjunctival and corneal surface of the eye. The overlying or surrounding eyelid skin may be red. [emedicinehealth.com] Entropion is the inward turning of either lower or upper eyelid, resulting in the eye lashes rubbing against the eye causing pain, redness and irritation. [murdocheye.com.au] Herpes Zoster Complications, such as corneal irritation or secondary bacterial infection of the vesicles, should be managed with routine therapies. [emedicine.medscape.com] In the advanced stages of this condition, haze and small blisters on the corneal surface may appear, causing pain and irritation. [my.clevelandclinic.org] Special care to prevent corneal injury is needed in patients who cannot close their eye, making it susceptible to foreign body irritation and abnormal drying. [drugtopics.com] Foreign Body in the Eye Any other Irritants Eye irrigation (warmed [33-37 ] solution [Evidence])for several minutes and then continue as for corneal abrasion. [emed.ie] Corneal FBs usually cause marked irritation, redness and watering, often with pain and a repeated blink reflex. [patient.info] This traps the irritant next to the eye and may cause more damage. You should wash out your eye right away while you wait for medical help. [icdlist.com] Epididymitis A cycle of increasing frequency of spasm caused by corneal irritation perpetuates the problem, often only interrupted by intervention. [ncbi.nlm.nih.gov] Complications Corneal irritation and injury are the most serious complications related to entropion because they can lead to permanent vision loss. [mayoclinic.org] This, in turn, causes ocular, specifically corneal irritation, due to lash rub which perpetuates the problem. Tarsoconjunctival contracture causes Cicatricial entropion. [ncbi.nlm.nih.gov] Pterygium When they are small, pterygia may not cause any concern at all, however, as they enlarge they may cause redness, irritation, corneal scarring, reduced vision, irregular astigmatism [qei.org.au] Our eye doctors and corneal specialist at New Eyes offer advanced treatment options to control the effects of pterygium. [neweyeslasvegas.com] It is important to remove a pterygium when it gets close to the central cornea as a permanent central corneal scar can result which will affect vision Causing irritation. [melbourneeyecentre.com.au] Heterozygous Familial Hypercholesterolemia Complications, such as corneal irritation or secondary bacterial infection of the vesicles, should be managed with routine therapies. [emedicine.medscape.com] Special care to prevent corneal injury is needed in patients who cannot close their eye, making it susceptible to foreign body irritation and abnormal drying. [drugtopics.com] Eyeball Injury Description: A corneal abrasion is a scratch over the clear part of the eye. It causes an irritable or sharp "foreign body" sensation in the eye. [utahmountainbiking.com] This is because some of the ingredients in eye drops can build up in the contact lens and cause irritation. [hse.ie] Otherwise, treat as for corneal abrasion. Pepper spray has the potential to cause severe and permanent damage to the corneo-conjunctival tissue. [patient.info] Conjunctivitis Complications can range from mild corneal irritation to severe visual loss, which develops in cases caused by extremely pathogenic bacteria, such as Chlamydia trachomatis [emedicine.medscape.com] […] from chemicals Foreign bodies and corneal abrasions. [pedclerk.bsd.uchicago.edu] English iritis, keratitis, corneal deposits, choroidal effusion, eye discharge, photophobia, eye irritation, allergic conjunctivitis, ocular discomfort, eyelid disorder, increased [mymemory.translated.net]
