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10 Possible Causes for Corneal Opacity, Palmar Hyperlinearity

  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[ncbi.nlm.nih.gov] PLATANUS OCCIDENTALIS 30 —Platanus occidentalis is prescribed for X linked ichthyosis with corneal opacity and cataract .[ks-gopi.blogspot.com] opacities Associated with steroid sulphatase deficiency in fibroblasts and elevated plasma cholesterol sulphate Only affects males May be associated with testicular disease[aocd.org]

  • Atopic Cataract

    We found a statistically significant correlation between minor criteria of AD like palmar hyperlinearity and combination of xerosis and Dennie-Morgan fold and the presence[ijdvl.com] In addition, measurement of intraocular pressures and corneal diameters are performed.[dovepress.com] […] children Flexure lichenification in older children and adults Minor features Eyes Cataracts (anterior subcapsular) Keratoconus Infraorbital folds affected Facial pallor Palmar[aafp.org]

  • X-Linked Ichthyosis

    The proband (ǁǀ5) is a 9 year-old boy with generalized dry and grey brown scales, without involvement of the palms, soles and face, and no palmar hyperlinearity, accompanied[ijdvl.com] Characteristic corneal opacities are small punctate or filiform lesions and are located in the deep corneal stroma.[ncbi.nlm.nih.gov] […] keratoderma in LK ( LOR ). ( f ) Palmar hyperlinearity in IV ( FLG ). ( g ) Generalized fine scaling phenotype with concomitant severe erythema in NS ( SPINK5 ). ( h ) Onychoschisis[ncbi.nlm.nih.gov]

  • Ichthyosis

    Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[campus.uni-muenster.de] Other classical signs include corneal opacities and undescended testicles, appearing respectively in 50% and in 5-20% of the cases. The disorder occurs only in males.[symptoma.com] There may be associated corneal opacities that do not affect vision.[ncbi.nlm.nih.gov]

  • Acquired Ichthyosis

    The phenotypic characteristics of ichthyosis vulgaris include palmar hyperlinearity, keratosis pilaris, and dry, scaly skin.[flipper.diff.org] opacities Cryptorchidism Testicular cancer Lamellar ichthyosis (an autosomal recessive congenital ichthyosis) Autosomal recessive 1:300,000 Birth Large, coarse, sometimes[merckmanuals.com] opacities in 50% Only affects males Undescended testicles in 5–20% Autosomal recessive congenital ichthyosis -1 (ARCI1) The baby is encased by collodion membrane at birth[dermnetnz.org]

  • Parana Hard-Skin Syndrome

    […] of their palmar skin and xerotic fish scale on their legs * Many genetic conditions, such as the large family of ichthyoses (including X-linked ichthyoses, Netherton\'s disease[checkorphan.org] Various additional features including coarse face, corneal opacities, gum hypertrophy, and EKG changes have been reported (summary by Zankl et al., 2007 ).[mendelian.co] […] itch * Ichthyoses vulgaris –Very common cause of dry skin –A genetic defect in skin barrier function, leading to a higher risk of atopic dermatitis –Patients often have hyperlinearity[checkorphan.org]

  • Generalized Follicular Keratosis

    It is characterized by palmar hyperlinearity, keratosis pilaris and a fine scale that is most prominent over the lower abdomen, arms, and legs.[nectarmutation.org] Some cases show association with corneal opacity, photophobia and palm-plantar hyperkeratosis that usually start in adolescence up to this moment a completely effective therapy[medigoo.com] Some cases may show an associated photophobia, corneal opacity, deafness, nail deformities and mental retardation. There may be numerous milia.[drmhijazy.com]

  • Congenital Non-Bullous Ichthyosiform Erythroderma ARCI 10

    When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[medicaljournals.se] opacities in 50% Only affects males Undescended testicles in 5–20% Autosomal recessive congenital ichthyosis -1 (ARCI1) The baby is encased by collodion membrane at birth[dermnetnz.org] There can also be significant pre-auricular involvement Scaling improves during summer and with age Extracutaneous features / associations Undescended testicles in 5–20% Corneal[pcds.org.uk]

  • Lamellar Ichthyosis Type 2

    When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[medicaljournals.se] opacities Cryptorchidism Testicular cancer Lamellar ichthyosis (an autosomal recessive congenital ichthyosis) Autosomal recessive 1:300,000 Birth Large, coarse, sometimes[merckmanuals.com] opacities in 50% Only affects males Undescended testicles in 5–20% Autosomal recessive congenital ichthyosis -1 (ARCI1) The baby is encased by collodion membrane at birth[dermnetnz.org]

  • Anonychia with Flexural Pigmentation

    hyperlinearity, keratosis pilaris • Pityriasis alba • Nipple eczema • White dermatographism and delayed blanch response • Anterior subcapsular cataracts, keratoconus • Elevated[slideshare.net] […] experience cheilitis, xerosis, dry nasal mucosa, dry eyes • Other, less common side effects: hair thinning (usually reversible), skin infection, petechiae, abdominal pain, corneal[slideshare.net] Chronic or relapsing dermatitis • Personal/family history of atopy Associated Features • Xerosis • Cutaneous infection • Nonspecific dermatitis of hands/feet • Ichthyosis, palmar[slideshare.net]

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