Create issue ticket

2,970 Possible Causes for Cornified Cell Envelope, Eosinophilia, Palmar Hyperlinearity

  • Atopic Dermatitis

    We present the case of a 6 year old patient that developed de novo atopic dermatitis, eosinophilia and high levels of total IgE under systemic treatment with tacrolimus.[] Among patients, reduced level of monomeric filaggrin and NMF correlated with the presence of FLG mutations and clinical phenotypes such as xerosis, palmar hyperlinearity and[] A major predisposing factor for AD is the existence in many patients of a mutation in the gene encoding for the filaggrin protein, which is a component of the cornified cell[]

  • Peeling Skin Syndrome Type A

    A rare autosomal recessive form of congenital, ichthyosis characterised by peeling of skin, erythema, pruritus, short stature, eosinophilia, increased IgE A rare autosomal[] Palmar and plantar areas are spared or present erythema, slight thickening of the skin or palmar hyperlinearity. An underlying erythroderma is present.[] A shortage of transglutaminase 5 weakens the cornified cell envelope, which allows the outermost cells of the epidermis to separate easily from the underlying skin and peel[]

  • Ichthyosis Vulgaris

    The main characteristics of IV are fine-scale on the arms and legs, palmar hyperlinearity, and keratosis pilaris.[] The resultant matrix is cross-linked to form a major component of the cornified cell envelope.[] cell envelope (CCE).[]

    Missing: Eosinophilia
  • Congenital Non-Bullous Ichthyosiform Erythroderma ARCI2

    \n\nIchthyosis prematurity syndrome (608649) is a self-improving form of\nichthyosis that includes respiratory complications at birth and\npersistent eosinophilia and is caused[] hyperlinearity were observed.[] Ichthyosis prematurity syndrome ({608649}) is a self-improving form of ichthyosis that includes respiratory complications at birth and persistent eosinophilia and is caused[]

  • Ichthyosis

    Consequently, defects in epidermal barrier function lead to pruritus, a susceptibility to skin infections and AD (often with elevation of total immunoglobulin E levels and eosinophilia[] Palms and soles show accentuated creases and when affecting the palms this sign is referred to as palmar hyperlinearity or as “ichthyosis palms”.[] cell envelope of the upper epidermis and leads to defective cornification and desquamation. [9], [10] The severity of symptoms can vary, from the mildest types such as ichthyosis[]

  • Peeling Skin Syndrome

    Three consanguinous newborn babies had a congenital ichthyosis with eosinophilia and elevated total immunoglobulin E.[] cornified cell envelope.[] Inflammatory/Type B PSS: Laboratory tests classically show evidence of atopy including eosinophilia and elevated IgE.[]

    Missing: Palmar Hyperlinearity
  • Acral Peeling Skin Syndrome

    Inflammatory/Type B PSS: Laboratory tests classically show evidence of atopy including eosinophilia and elevated IgE.[] Cystatin A is a protease inhibitor found in the cornified cell envelope, and loss-of-function mutations have previously been reported in two cases of exfoliative ichthyosis[] Some cases result from mutations in the TGM5 gene that encodes transglutaminase 5, which has an important role in cross-linking cornified cell envelope proteins.[]

    Missing: Palmar Hyperlinearity
  • Atopy

    It can be concluded that nasal cytology with eosinophilia assessment can be a useful tool for an early diagnosis of atopic disease in children.[] Smoking, age above 40 years, and blood eosinophilia may affect a good outcome for atopy. Poorly controlled asthma may lead to many long-term changes in the body.[] Weiss Asthma, hay fever, and phlegm production associated with distinct patterns of allergy skin test reactivity, eosinophilia, and serum IgE levels [4.] L.R.[]

    Missing: Cornified Cell Envelope Palmar Hyperlinearity
  • Lamellar Ichthyosis

    , rheumatism, dermatitis; articular nodules, dermographism, episodic hand & foot edema, eosinophilia, generalized pruritic dermatitis, urticaria Netherton's s.[] Ultrastructural examination revealed incomplete formation of cornified cell envelopes and electron-dense materials adjacent to plasma membranes.[] Malformation of the cornified cell envelope (CCE) arising from mutations of the transglutaminase (TGase) 1 gene (TGM1) is the cause of some cases of lamellar ichthyosis (LI[]

    Missing: Palmar Hyperlinearity
  • Ichthyosis-Prematurity Syndrome

    When examined at 2–37 years of age, all patients exhibited skin xerosis, fine or focal scaling (Fig. 1c), palmar hyperlinearity or keratoderma, and frequent occurrence of[] Many patients also develop food/respiratory allergies with elevated IgE levels and eosinophilia.[] […] characterized by premature birth (at gestational weeks 30-32, in general) in addition to thick, caseous and desquamating epidermis, neonatal respiratory asphyxia, and persistent eosinophilia[]

Similar symptoms