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866 Possible Causes for cornea, Hyperuricemia

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  • Essential Hypertension

    Lubrication to protect the cornea is required in severe cases.[] Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol 2002; 283 : F1105–F1110. 15.[] Apply lubrication to exposed cornea. Click here for Patient Education[]

  • Hypertension

    The aqueous flows through the pupil and fills the anterior chamber of the eye, which is the space between the iris and the cornea .[] Epidemiological and experimental studies suggest a linkage between hyperuricemia and hypertension. Hyperuricemia affects 25-40 % of patients with untreated hypertension.[] Hypertension is a result of disruptions in the aqueous humour, the fluid substance that fills the anterior chamber of the eye and helps to keep the cornea functioning properly[]

  • Gout

    Crystal deposition in the cornea is extremely rare and may be a cause of peripheral ulcerative keratitis.[] Hyperuricemia and gout, the clinical manifestation of monosodium urate crystal deposition, are common in patients with chronic kidney disease (CKD).[] Over the past decade, significant advances have been made regarding the pathogenesis, clinical implications, and treatment of hyperuricemia.[]

  • Diabetes Mellitus

    In severe retinopathy, neovascularization may lead to adhesions (synechiae) between iris and cornea or iris and lens.[] Fructose is also the only sugar able to increase blood uric acid concentrations, and SSB consumption has been linked to development of hyperuricemia (serum uric acid level[] Shrestha Priyadarsini, Akhee Sarker-Nag, Jeremy Allegood, Charles Chalfant and Dimitrios Karamichos, Description of the Sphingolipid Content and Subspecies in the Diabetic Cornea[]

  • Acute Polyarticular Gouty Arthritis

    Cornea. 2010;29 (7):830-832. PubMed Google Scholar Iacobellis G. A rare and asymptomatic case of mitral valve tophus associated with severe gouty tophaceous arthritis.[] Hyperuricemia Primary hyperuricemia Primary hyperuricemia is aggravated by poor dietary habits![] Besides the cornea, the iris, anterior chamber, lens, and sclera have been found to harbor urate crystals; on postmortem examination, urate crystals have also been found in[]

  • Arteriosclerosis

    (white or grey rings around the cornea) constitutes an independent risk factor for cardiovascular disease.[] […] retinal ischemia, cerebral infarction, and renal failure The Copenhagen City Heart Study found that xanthelasmata (raised yellow patches around the eyelids) but not arcus corneae[]

  • Multiple Myeloma

    Ophthalmic explorations showed bilateral macular and papillary edema, and multiple crystalline deposits in the anterior stromal cornea and in the retina.[] Not recognizing hyperuricemia.[] In 1994, D'Amato et al 61 described for the first time the significant antiangiogenic properties of thalidomide in the rabbit cornea micropocket assay.[]

  • Sarcoidosis

    Calcium deposits in connective tissue or the cornea, tear duct enlargements or retinal vasculitis may also occur.[] Almost any part of the eye can be affected -- the membranes of the eyelids, cornea, outer coat of the eyeball (sclera), retina, and lens.[] Since both may manifest with hyperuricemia and similar clinical findings, demonstration of monosodium urate crystals phagocytozed by neutrophils is diagnostic.[]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Sebastian & Endi Wang Annals of Hematology (2016) BCR-ABL1- positive chronic myeloid leukemia with erythrocytosis presenting as polycythemia vera: a case report Mihaela I Precup Cornea[] Other Remarkable laboratory findings include a significantly increased vitamin B-12–binding protein (TC-I) and hyperuricemia, The former is indicative of leukocytosis and[]

  • Hyperlipoproteinemia Type 5

    SOSTITUITA DA TRAPIANTO SOGGETTI SOTTOPOSTI A TRAPIANTO DI CORNEA ILLIMITATA 054.720.0 SPONDILITE ANCHILOSANTE SPONDILITE ANCHILOSANTE ILLIMITATA ILLIMITATA PER ASMA CRONICO[] It is also associated with glucose intolerance and hyperuricemia Hyperlipoproteinemia Type 5 Pancreatitis, Eruptive Xanthomas, Adults, 5% of total Hyperlipoproteinemia Type[] […] usually appears first in adulthood,this phenotype is often associated with secondary factors,almost always Diabetes Mellitus .May be associated with Eruptive Xanthomas and Hyperuricemia[]

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