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866 Possible Causes for cornea, Hyperuricemia

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  • Essential Hypertension

    Lubrication to protect the cornea is required in severe cases.[merckmanuals.com] Mild hyperuricemia induces glomerular hypertension in normal rats. Am J Physiol 2002; 283 : F1105–F1110. 15.[doi.org] Apply lubrication to exposed cornea. Click here for Patient Education[msdmanuals.com]

  • Hypertension

    The aqueous flows through the pupil and fills the anterior chamber of the eye, which is the space between the iris and the cornea .[allaboutvision.com] Epidemiological and experimental studies suggest a linkage between hyperuricemia and hypertension. Hyperuricemia affects 25-40 % of patients with untreated hypertension.[ncbi.nlm.nih.gov] Hypertension is a result of disruptions in the aqueous humour, the fluid substance that fills the anterior chamber of the eye and helps to keep the cornea functioning properly[vsp.com]

  • Gout

    Crystal deposition in the cornea is extremely rare and may be a cause of peripheral ulcerative keratitis.[ncbi.nlm.nih.gov] Hyperuricemia and gout, the clinical manifestation of monosodium urate crystal deposition, are common in patients with chronic kidney disease (CKD).[ncbi.nlm.nih.gov] Over the past decade, significant advances have been made regarding the pathogenesis, clinical implications, and treatment of hyperuricemia.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    In severe retinopathy, neovascularization may lead to adhesions (synechiae) between iris and cornea or iris and lens.[library.med.utah.edu] Fructose is also the only sugar able to increase blood uric acid concentrations, and SSB consumption has been linked to development of hyperuricemia (serum uric acid level[doi.org] Shrestha Priyadarsini, Akhee Sarker-Nag, Jeremy Allegood, Charles Chalfant and Dimitrios Karamichos, Description of the Sphingolipid Content and Subspecies in the Diabetic Cornea[doi.org]

  • Acute Polyarticular Gouty Arthritis

    Cornea. 2010;29 (7):830-832. PubMed Google Scholar Iacobellis G. A rare and asymptomatic case of mitral valve tophus associated with severe gouty tophaceous arthritis.[panafrican-med-journal.com] Hyperuricemia Primary hyperuricemia Primary hyperuricemia is aggravated by poor dietary habits![amboss.com] Besides the cornea, the iris, anterior chamber, lens, and sclera have been found to harbor urate crystals; on postmortem examination, urate crystals have also been found in[emedicine.medscape.com]

  • Arteriosclerosis

    (white or grey rings around the cornea) constitutes an independent risk factor for cardiovascular disease.[emedicine.com] […] retinal ischemia, cerebral infarction, and renal failure The Copenhagen City Heart Study found that xanthelasmata (raised yellow patches around the eyelids) but not arcus corneae[emedicine.com]

  • Multiple Myeloma

    Ophthalmic explorations showed bilateral macular and papillary edema, and multiple crystalline deposits in the anterior stromal cornea and in the retina.[ncbi.nlm.nih.gov] Not recognizing hyperuricemia.[clinicaladvisor.com] In 1994, D'Amato et al 61 described for the first time the significant antiangiogenic properties of thalidomide in the rabbit cornea micropocket assay.[doi.org]

  • Sarcoidosis

    Calcium deposits in connective tissue or the cornea, tear duct enlargements or retinal vasculitis may also occur.[lecturio.com] Almost any part of the eye can be affected -- the membranes of the eyelids, cornea, outer coat of the eyeball (sclera), retina, and lens.[medicinenet.com] Since both may manifest with hyperuricemia and similar clinical findings, demonstration of monosodium urate crystals phagocytozed by neutrophils is diagnostic.[doi.org]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Sebastian & Endi Wang Annals of Hematology (2016) BCR-ABL1- positive chronic myeloid leukemia with erythrocytosis presenting as polycythemia vera: a case report Mihaela I Precup Cornea[nature.com] Other Remarkable laboratory findings include a significantly increased vitamin B-12–binding protein (TC-I) and hyperuricemia, The former is indicative of leukocytosis and[symptoma.com]

  • Hyperlipoproteinemia Type 5

    SOSTITUITA DA TRAPIANTO SOGGETTI SOTTOPOSTI A TRAPIANTO DI CORNEA ILLIMITATA 054.720.0 SPONDILITE ANCHILOSANTE SPONDILITE ANCHILOSANTE ILLIMITATA ILLIMITATA PER ASMA CRONICO[ausl.bologna.it] It is also associated with glucose intolerance and hyperuricemia Hyperlipoproteinemia Type 5 Pancreatitis, Eruptive Xanthomas, Adults, 5% of total Hyperlipoproteinemia Type[memorize.com] […] usually appears first in adulthood,this phenotype is often associated with secondary factors,almost always Diabetes Mellitus .May be associated with Eruptive Xanthomas and Hyperuricemia[wikidoc.org]

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