Possible Causes for cortical thickening Infantile Cortical Hyperostosis Distinct skeletal dysplasias feature variable degrees of cortical thickening. [rrnursingschool.biz] Frontal view shows cortical thickening of the mandible, which is depicted as a double contour of the cortex due to subperiosteal new bone formation. [emedicine.medscape.com] Thickening of bone cortex may be secondary to overproduction or diminished resorption of cortical bone. [rrnursingschool.biz] Melorheostosis Melorheostosis is a very rare disorder characterized by irregular cortical thickening seen on radiographs. [ncbi.nlm.nih.gov] thickening of long (tubular) bones which, when stripped of muscle, simulates a candle with wax melted down a side. [medical-dictionary.thefreedictionary.com] thickening of long–tubular bones which, when stripped of muscle, simulates a candle with wax dribbled down a side Clinical Pain, limitation of movement, contraction and/or [medical-dictionary.thefreedictionary.com] Facial Dysmorphism-Immunodeficiency-Livedo-Short Stature Syndrome Our wines Père et fils Since 1791, eight generations of the Miquel family have worked the vines of their estate high in the Languedoc hills. Father to Son, harvest after harvest, they have deepened their knowledge of the fickle nature of the vines and have learned to work in harmony with nature. Laurent, the[…] [laurent-miquel.com] Kenny-Caffey Syndrome Type 1 Clinical features include cortical thickening and medullary stenosis of the tubular bones, delayed closure of fontanels, defective dentition, small eyes with hypermetropia [malacards.org] OMIM : 57 Kenny-Caffey syndrome is characterized by severe proportionate short stature, cortical thickening and medullary stenosis of the tubular bones, delayed closure of [malacards.org] […] diseases and orphan drugs.Orpha Number: 93324Disease definitionA rare, primary bone dysplasia characterized by prenatal and postnatal growth retardation, short stature, cortical [malacards.org] Camurati-Engelmann Syndrome Radiographic studies in the two girls demonstrated not only diaphyseal dysplasia (cortical thickening of the diaphyses) resembling that of progressive diaphyseal dysplasia [ncbi.nlm.nih.gov] thickening of the diaphyses. [iofbonehealth.org] The hallmark of the disorder is the cortical thickening of the diaphyses of the long bones. [doi.org] Hereditary Hyperphosphatasia Distinct skeletal dysplasias feature variable degrees of cortical thickening. [rrnursingschool.biz] Roentgenologically, the bone of the cranial vault was thickened and sclerotic. Cortical thickening and lateral bowing of the long bone was characteristic. [jstage.jst.go.jp] Diffuse sclerosis with cortical thickening involving the right femur and both iliac bones. [slideshare.net] Osteosclerosis Imaging work-up showed diaphyseal asymmetric intramedullary sclerosis with cortical thickening. No periosteal reaction or other soft-tissue abnormalities were apparent. [ncbi.nlm.nih.gov] Diffuse sclerosis with cortical thickening involving the right femur and both iliac bones. [slideshare.net] A 46-year-old female presented with symmetrical sclerotic cortical thickening of the anterior mandible visible on radiograph, with no other major clinical examination findings [ncbi.nlm.nih.gov] Weismann-Netter Syndrome thickening of both bones and short stature. [orpha.net] The diagnostic findings of WNS are anterior bowing of the diaphyses of tibia and fibula, broadening or "tibialization" of the fibula and posterior cortical thickening of the [ncbi.nlm.nih.gov] A rare disorder in which there is an anterior bowing and posterior cortical thickening of the diaphyses of both tibiae and fibulae. [medindia.net] Brodie Abscess One third of the lesions were diaphyseal in location, and 50% had associated cortical thickening, while 40% showed a stimulated periosteal reaction, and 20% contained sequestra [ncbi.nlm.nih.gov] Stress Fracture Another common cause of focal cortical thickening, or uninterrupted periosteal reaction, is a stress fracture. [jaocr.org] There is cortical thickening, sclerosis and a layered periosteal reaction. [radiologyassistant.nl] Sanjad-Sakati Syndrome Cortical thickening of bones (osteosclerosis) and hypocalcemia. [accessanesthesiology.mhmedical.com] The typical findings of cortical thickening and medullary stenosis were not described in SSS, [8] making the diagnosis of KCS 1 more probable. [avicennajmed.com] thickening of long bones with medullary stenosis, macrocephaly or normocephaly, normal mentality and immune deficiency. [alliedacademies.org] Malignant Neoplasm of the Bone •cortical thickening without aggressive periosteal reaction is often seen. •tumour extension into medullary canal,freqently 14. string sign 15. [slideshare.net] […] expansion with cortical thickening of the bone. • CHS present as an area of radiolucency with variably distributed punctate or ring-like opacities(mineralization). • Cortical [pedorthpath.com] Radiographically, these lesions are radiolucent, cortical lesions that are surrounded by bony sclerosis and cortical thickening, and are usually less than 1 cm in diameter [podiatrytoday.com] Hyperostosis Frontalis Interna […] women suggest possible hormonal influence Clinical Findings No known clinical significance May be more prevalent with obesity Imaging Findings Bilateral and symmetrical Cortical [learningradiology.com] Saturday, 20 August 2011 Hyperostosis Frontalis Interna Cortical thickening confined to inner table of the skull noted as an incidental finding. [neuroradiologycases.com] […] hyperostosis a syndrome seen in infants under six months of age, marked by fever, arthralgias, and swelling and cortical thickening of facial, trunk, and long bones. [medical-dictionary.thefreedictionary.com] Juxtacortical Osteosarcoma thickening without aggressive periosteal reaction is often seen tumor extension into the medullary cavity is frequently seen MRI It exhibits predominantly low signal intensity [radiopaedia.org] […] separating the tumor from the cortex, seen in 30% of cases tumor stalk: grows within tumor in late stages and obliterates the radiolucent cleavage plane /- soft tissue mass cortical [radiopaedia.org] Paget Disease of the Bone Type 5 During adulthood, cortical thickening, osteosclerosis, and bowing affected these bones. Serum alkaline phosphatase (ALP) activity was persistently elevated. [ncbi.nlm.nih.gov] There is also marked cortical thickening. Radiographs of the hands and feet reveal widened phalanges with demineralization and marked cortical thickening. [roentgenrayreader.blogspot.com] In the pelvis, cortical thickening and sclerosis of the iliopectineal and ischiopubic lines are present. Pubic rami and ischia may enlarge. [radiologykey.com] Osteoid Osteoma Initial plain radiographs demonstrated cortical thickening and a lytic lesion at the proximal diaphysis of the fifth metatarsal. [ncbi.nlm.nih.gov] thickening and vascular fibrous stroma and sclerosis. [ncbi.nlm.nih.gov] Plain radiograph May be normal or may show a solid periosteal reaction with cortical thickening. [radiopaedia.org] Osteoma Note the adjacent endosteal and cortical thickening. [emedicine.com] (arrow), the cause of the cortical thickening and edema. [radsource.us] Matrix Lucent nidus may or may not be partially calcified centrally Cortex Intact, may cause marked cortical thickening Soft tissue mass None, except in the rare subperiosteal [orthopaedicsone.com] Stuve-Wiedemann Syndrome The skeletal radiographic changes include short and broad long bones, large metaphyses, internal cortical thickening, and angulation primarily of tibiae and femora, but also [ncbi.nlm.nih.gov] The long bones display cortical thickening and an abnormal trabecular pattern. The metaphyses are wide, flared, rarefied and striated. read more [ctgt.net] thickening, wide metaphyses with abnormal trabecular pattern, and campodactyly. [checkorphan.org] Van Buchem Disease Hyperostosis Corticalis Generalisata, benign form of worth with Torus Palatinus: This condition is characterized by cortical thickening of the long bones without alteration [genedx.com] The main findings include cortical thickening of the long bones and progressive enlargement of the mandible with decreased gonial angle and the development of torus palatinus [ctgt.net] Gene SOST gene, 17q21.31 (OMIM gene/locus number #60574 0 ) Phenotype Progressive skeletal overgrowth (especially skull) and cortical thickening and generalized osteosclerosis [iofbonehealth.org] Cystitis Congenital Coxa Vara cortices are thickened and may be associated with overlying skin dimples External rotation of the femur with valgus deformity of knee may be noted [slideshare.net] Fracture CONCLUSIONS: An atlas with arcuate foramen presents cortical bone thickening. [ncbi.nlm.nih.gov] Radiographic findings of this case differed from previously reported cases of ulnar fracture in terms of showing a transverse fracture line with cortical thickening and an [ncbi.nlm.nih.gov] As a result, we aimed to test in an experimental model if there is a cortical bone thickening in an atlas vertebra which has an arcuate foramen that may play a protective [ncbi.nlm.nih.gov] Primary Hypertrophic Osteoarthropathy Radiologic studies of his limbs demonstrated subperiostial bone formation with bone density and cortical thickening ( Fig. 3 ). [edmcasereports.com] Cortical thickening with widening of the femoral shafts was noted bilaterally. [doi.org] Other abnormalities: Cortical thickening without narrowing of the medullary cavity Enlargement of the paranasal sinuses 32. [slideshare.net] Lenz-Majewski Syndrome thickening; metaphyseal and epiphyseal hypostosis; and retarded skeletal maturation. [doi.org] Diaphyseal undermodeling and midshaft cortical thickening. Retarded skeletal maturation, humeroradial synostosis. [accessanesthesiology.mhmedical.com] […] include progressive sclerosis of the skull, facial bones, and vertebrae; broad clavicles and ribs; short or absent middle phalanges; diaphyseal undermodeling and midshaft cortical [doi.org] Facial Hemiatrophy CT and MR findings included unilateral focal infarctions in the corpus callosum, diffuse deep and subcortical white matter signal changes, mild cortical thickening, and leptomeningeal [ncbi.nlm.nih.gov] CT of the brain reveals focal cerebral hypodensities and intracranial calcifications; and MRI show focal white matter enhancement, cortical thickening and meningeal enhancement [ncbi.nlm.nih.gov] Exostosis These bony protruberance caused by the thickening or enlargement of the cortical plate of the facial surface of the maxilla without any systemic abnormality helped to reach [ncbi.nlm.nih.gov] Paget Disease of the Bone Cortical thickening and typical "swiss cheese" appearance of bone are also well demonstrated. Bone scan: -Helpful in determining extent of disease. [uwmsk.org] CT image of the first sacral vertebra demonstrates marked cortical thickening (arrows) and trabecular coarsening. Courtesy of Lee F. Rogers. [emedicine.com] […] more delicate pattern seen in intraosseous hemangiomas with which it may be confused Pelvis cortical thickening and sclerosis of the iliopectineal and ischiopubic lines results [radiopaedia.org] Calvarial Doughnut Lesions - Bone Fragility Syndrome conditions with increased bone density and cortical thickening (van Buchem and Worth type of endosteal hyperostosis, sclerosteosis, Camurati-Engelmann disease, hyperphosphatasia [rrnursingschool.biz] Conventional histologic studies show changes, including decreased orbicular bone volume, thin cortices, a reduced calcification rate, and thickened periosteum with a defective [radiologykey.com] Diaphyseal expansion with irregular, cortical thickening involving the mid-dia-physes of the long tubular bones, and narrowing of the medullary cavity are striking features [rrnursingschool.biz] Familial Paget Disease of Bone CT image of the first sacral vertebra demonstrates marked cortical thickening (arrows) and trabecular coarsening. Courtesy of Lee F. Rogers. [emedicine.com] His skull is enlarged with cortical thickening and areas of increased resorption. He also has hearing loss. [nof.org] Subsequently, areas of sclerosis develop, leading to the characteristic appearances of mixed lytic and sclerotic areas, thickened trabeculae, bone expansion, cortical thickening [mja.com.au] Periodontitis The author’s findings included: ulcerations on the gingival mucosa, periodontal pockets, thickening of the periodontal ligament space, and loss of the alveolar cortical bone [doi.org] Leontiasis due to Leprosy thickening and sclerosis, and finally, it can have a mixed pattern presentation. [imagejournals.org] Panel C shows diffuse cortical thickening on a lateral skull X-ray with soft tissue thickening and elevation of the nasal bridge. [doi.org] […] in the active or osteolytic phase, aggressive bone resorption and lytic appearance are the hallmarks while on the quiescent and inactive stage there is a predominance of cortical [imagejournals.org] Chronic Pyogenic Osteomyelitis […] with a draining sinus track, in addition to cortical thickening and periosseous soft-tissue edema. [radiologykey.com] Radiographic findings include periosteal thickening or elevation, as well as cortical thickening, sclerosis, and irregularity. [boneandspine.com] Computed tomography scan of the right patella revealed characteristic features of chronic osteomyelitis such as abnormal thickening of the affected cortical bone, with sclerotic [mjmsr.net]
